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The map label for this gene is minC

Identifier: 120599064

GI number: 120599064

Start: 2607953

End: 2608618

Strand: Direct

Name: minC

Synonym: Sputw3181_2260

Alternate gene names: 120599064

Gene position: 2607953-2608618 (Clockwise)

Preceding gene: 120599061

Following gene: 120599065

Centisome position: 55.39

GC content: 47.15

Gene sequence:

>666_bases
ATGTCAAAACCTAGCTTAGAGTTAAAAGGAGCTTCTTTTACTCTTTCAGTGCTTCACATTAATAGCAGTGACTTAAATGC
AGTCATGGCTGAATTAGATAGCAAATTGGCACAAGCCCCACAATTTTTTCTGGGCGCGCCTTTGGTGGTCAATCTCAGTG
CCATCCAGCATAATGATTTTAATTTACATGGCCTCAAGGAACTACTGCTCTCTCGTCAATTAGTGATTGTTGGGATAACG
GGCGCGACAACCGTTCTCAGTAAGCAGGCCAAAGACTTAGGTCTTGCCATAGTCAAAGCGGGTAAACAAAGCACAACGCC
CCCCCCTGCGCCACGCCAAACTAAAATCGTTAAACAAAATATCCGCTCCGGGCAGCAGGTCTATGCAAAAAATGGGGATT
TAATCATATTTGGTGCGGTAGGCAATGGCGCTGAAGTCATTGCTGATGGTAGCATTCATATCTATGGCGCATTACGAGGG
AAAGCCATGGCGGGCGCGGCGGGCGATCCCACAGCCGTCATCATCGCCCACTCTCTTGAGGCCGAACTCGTTTCGATAGC
AGGGCAATATTGGCTCGCTGAAAATCTACAACAACATAGCTCAGATAAAAGCGGCTGTATTCGCTTAAATGGCGAGTCGC
TTATGGTTGAATCATTGCCCCTCTAA

Upstream 100 bases:

>100_bases
CAAACTTGCCAGCCAATGGGGCACACTATAACATGGTCGCCTAATAATTTAATTGCAAAATCAGCGAACCGACTGATGAT
TTCTTAAGAAGAGTGCCGGG

Downstream 100 bases:

>100_bases
ATGGCAGAAAAAAGGATAGAGAGAAACATGGCACAAATTATTGTTGTCACTTCAGGTAAAGGCGGTGTAGGTAAAACCAC
ATCGAGTGCTGCTATTGCGA

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDFNLHGLKELLLSRQLVIVGIT
GATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRG
KAMAGAAGDPTAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL

Sequences:

>Translated_221_residues
MSKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDFNLHGLKELLLSRQLVIVGIT
GATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRG
KAMAGAAGDPTAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL
>Mature_220_residues
SKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDFNLHGLKELLLSRQLVIVGITG
ATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGK
AMAGAAGDPTAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=231, Percent_Identity=37.6623376623377, Blast_Score=161, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 23210; Mature: 23079

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDF
CCCCCEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCC
NLHGLKELLLSRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQN
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHH
IRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDPTAVIIAHSLE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCH
AELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCC
>Mature Secondary Structure 
SKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDF
CCCCEEECCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEEECCCC
NLHGLKELLLSRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQN
CHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCHHHHHHHH
IRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDPTAVIIAHSLE
HCCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCCEEECCCCCCEEEEEEECCH
AELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA