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The map label for this gene is hypE [H]

Identifier: 120598984

GI number: 120598984

Start: 2508863

End: 2509879

Strand: Direct

Name: hypE [H]

Synonym: Sputw3181_2176

Alternate gene names: 120598984

Gene position: 2508863-2509879 (Clockwise)

Preceding gene: 120598983

Following gene: 120598985

Centisome position: 53.29

GC content: 48.38

Gene sequence:

>1017_bases
ATGGGTGATACACCAAAAGATAAATCCATTCAACTCAGTCACGGCGGTGGCGGCAAAGAGATGAACAAACTCATTCGCGA
TCTATTTTTTGCTGAGTTTGATAATCCCATCCTTCGCAGCGAAGAAGATGCTGCAAAACTTGACTTACATGGCGCCAATG
CTTTTACCACGGACTCTTTCACTGTATCGCCCCTATTTTTTGCCGGCGGTGATATCGGCAAGCTTGCTATCGCGGGCACT
GTTAACGATCTCGCCATGATGGGCGCTGAACCTCAGTATTTGAGTTGCAGTGTGATTATAGAAGAAGGTTTTTCTATCAA
TGACTTAACCACAATCGTCCGCAGTATGGCCAAAGAATTAAAACAAAGTGGTGCACGGATTGTTTGCGGCGATACTAAGG
TTGTCCCCAAGGGCTGCGCCGATGGTTTATTTATTAACACATCAGGTATTGGCCGCATCCTGCGTCCCAATATCTCGGCT
GCAAATCTCACTGCGGGCGATACGATTATTGTCTCCCGTGATATTGGCTGTCACGGTGCGGCCATTTTAATGGCTCGTGA
AGGTTTAGTGCTCGAATCAGCGCTGCAAAGCGATTGCGCGACGCTCTGGCCCGTCGTGGAGCAGTTGATTGCCGCCAATA
TTCCCATTCATGCGATGCGTGATGCCACTCGCGGTGGTTTATCAGCGGTATTAAATGAGTGGGCGGTTGCATCCAATGTT
GGTATCACAGTGAATGAAGCGAGTATTCCTGTTTGTGATGAAGTCAAAGGCTTATGTGAACTCTATGGCTTTGAAGCCAT
GGATCTCGCCAATGAAGGCACCTTTGTCCTTGCTGTACCTCAGGAGATTGCCTTAGGTGCGCTCGAGATTATGCAGCGTT
TTGGTCACTGTGAACAGGCTGCCATTATCGGCACGGTTACAGATGAAACCGCAGGGAAAGTGATTTTAAAAACCCCGTGG
AATACCAAGCGCTATCTCGATCTTCCCCAAGGTGAACTGCTGCCAAGGATTTGCTGA

Upstream 100 bases:

>100_bases
TGCAACCCTGAAACGCCATTAGGCAGTTGTATGGTCAGCTCTGAAGGCGCCTGCAATGCCTATTACCGCTATCAAGGCGT
CGATATTAAGGAGCCACATC

Downstream 100 bases:

>100_bases
TGCATGAATATTCGATTGTGAGTGCCCTGATTGAGCAATGTGAACAACACGCGCTCGCCAATCAGGCAAATAAGATCACT
CGGGTAGAGATTAAACTTGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MGDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGT
VNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISA
ANLTAGDTIIVSRDIGCHGAAILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQAAIIGTVTDETAGKVILKTPW
NTKRYLDLPQGELLPRIC

Sequences:

>Translated_338_residues
MGDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGT
VNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISA
ANLTAGDTIIVSRDIGCHGAAILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQAAIIGTVTDETAGKVILKTPW
NTKRYLDLPQGELLPRIC
>Mature_337_residues
GDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGTV
NDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAA
NLTAGDTIIVSRDIGCHGAAILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNVG
ITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQAAIIGTVTDETAGKVILKTPWN
TKRYLDLPQGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=340, Percent_Identity=48.2352941176471, Blast_Score=284, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35921; Mature: 35790

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSF
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCCEECCCE
TVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKEL
EECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAANLTAGDTIIVSRDIGCHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCEECCCCEEEEEECCCCCCE
AILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCC
GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQA
CEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCE
AIIGTVTDETAGKVILKTPWNTKRYLDLPQGELLPRIC
EEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
GDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSF
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCCEECCCE
TVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKEL
EECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAANLTAGDTIIVSRDIGCHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCEECCCCEEEEEECCCCCCE
AILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCC
GITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQA
CEEEECCCCCHHHHHHHHHHHHCCHHEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCE
AIIGTVTDETAGKVILKTPWNTKRYLDLPQGELLPRIC
EEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]