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The map label for this gene is hypD2 [H]

Identifier: 120598983

GI number: 120598983

Start: 2507731

End: 2508870

Strand: Direct

Name: hypD2 [H]

Synonym: Sputw3181_2175

Alternate gene names: 120598983

Gene position: 2507731-2508870 (Clockwise)

Preceding gene: 120598982

Following gene: 120598984

Centisome position: 53.26

GC content: 49.47

Gene sequence:

>1140_bases
ATGCTTGAACTAAAACACCTCTACCAAGGCTTTCGCGATCCCCAGACTATCGCCAATTTGGCGCGGGACATTCAGCTAAC
GGCTAAAACGATCAAGCAACAAATCAATATTATGGAGGTGTGTGGTGGCCATACCCACACCATAATGAAATACGGTTTGT
TGGATTTACTGCCGGATAATATTGAATTTATCCACGGCCCGGGTTGCCCTGTATGCGTGATGCCAAAGGAACGTATCGAC
CAAGCCGCAGCGCTTGCCTCCCAAGAAAATGTGATCCTTGTGACGCTGGGCGATATGATCCGCGTGCCCGGTTCTCAAGG
CTCTTTAGCCAGTTTTAGGGCTAAAGGCTGCGATATCCGCCCGATTTACGATCCCTTAGATACGCTCAAAATTGCCCGTG
ATAACCCCGATAAAATCGTTGTTTTTTTCGCCATAGGTTTTGAAACCTCAACGCCAATGACGGCAATTCTGCTTCAACTC
GCCGAACATGAAAAACTCGATAACCTGCTTTTCCATATCAACCATGTATTAGTGCCTCCTGCCATTGATGCCGTCATGCA
CGATCCTAATGCGCGAGTGAATGCCTTTATTGGCCCGGCCCATGTCAGTGTGATAAGTGGCGCTAAAATCTACCGCCCAG
CGGTCGCACAATATGGCACACCCGTAGTGGTCTCAGGTTTTGAACCTGTCGATGTAATGGAATCCATCCTGCGTATTGTC
CGACAAAAAGCGGCAGGGAAAGCCGAGCTTGATATCCAATATAGCCGCGCCGTATCAGAGGATGGCAATCTCACAGCACA
AGCTAAAGTGAACCAATTCTTTAGTGTTAGACCGCAATTTCGCTGGCGCGGCCTTGGCCCAATACCCAATTCAGCGCTGC
AACTCAGACCTGAATATGCCCATAGAGACGCCGAACTACGGTTTAAAGATCGCTTGCCCGTGAAAGAAATTGATGATCAT
AAGGCCTGTCAGTGCGGTGATATTCTTCGCGGCCTCGCGAAGCCTAAGGACTGCAAAGTCTTTGGCCGAGGTTGCAACCC
TGAAACGCCATTAGGCAGTTGTATGGTCAGCTCTGAAGGCGCCTGCAATGCCTATTACCGCTATCAAGGCGTCGATATTA
AGGAGCCACATCATGGGTGA

Upstream 100 bases:

>100_bases
GAAATCGTCACAAAACTTGAAAATGAAGCCATGCATTAACCCACATTAAATCCTTTTTCGATAAAAGGCGTGCGCTCAAT
CAGCGCACCAAGGAAAGAGA

Downstream 100 bases:

>100_bases
TACACCAAAAGATAAATCCATTCAACTCAGTCACGGCGGTGGCGGCAAAGAGATGAACAAACTCATTCGCGATCTATTTT
TTGCTGAGTTTGATAATCCC

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLELKHLYQGFRDPQTIANLARDIQLTAKTIKQQINIMEVCGGHTHTIMKYGLLDLLPDNIEFIHGPGCPVCVMPKERID
QAAALASQENVILVTLGDMIRVPGSQGSLASFRAKGCDIRPIYDPLDTLKIARDNPDKIVVFFAIGFETSTPMTAILLQL
AEHEKLDNLLFHINHVLVPPAIDAVMHDPNARVNAFIGPAHVSVISGAKIYRPAVAQYGTPVVVSGFEPVDVMESILRIV
RQKAAGKAELDIQYSRAVSEDGNLTAQAKVNQFFSVRPQFRWRGLGPIPNSALQLRPEYAHRDAELRFKDRLPVKEIDDH
KACQCGDILRGLAKPKDCKVFGRGCNPETPLGSCMVSSEGACNAYYRYQGVDIKEPHHG

Sequences:

>Translated_379_residues
MLELKHLYQGFRDPQTIANLARDIQLTAKTIKQQINIMEVCGGHTHTIMKYGLLDLLPDNIEFIHGPGCPVCVMPKERID
QAAALASQENVILVTLGDMIRVPGSQGSLASFRAKGCDIRPIYDPLDTLKIARDNPDKIVVFFAIGFETSTPMTAILLQL
AEHEKLDNLLFHINHVLVPPAIDAVMHDPNARVNAFIGPAHVSVISGAKIYRPAVAQYGTPVVVSGFEPVDVMESILRIV
RQKAAGKAELDIQYSRAVSEDGNLTAQAKVNQFFSVRPQFRWRGLGPIPNSALQLRPEYAHRDAELRFKDRLPVKEIDDH
KACQCGDILRGLAKPKDCKVFGRGCNPETPLGSCMVSSEGACNAYYRYQGVDIKEPHHG
>Mature_379_residues
MLELKHLYQGFRDPQTIANLARDIQLTAKTIKQQINIMEVCGGHTHTIMKYGLLDLLPDNIEFIHGPGCPVCVMPKERID
QAAALASQENVILVTLGDMIRVPGSQGSLASFRAKGCDIRPIYDPLDTLKIARDNPDKIVVFFAIGFETSTPMTAILLQL
AEHEKLDNLLFHINHVLVPPAIDAVMHDPNARVNAFIGPAHVSVISGAKIYRPAVAQYGTPVVVSGFEPVDVMESILRIV
RQKAAGKAELDIQYSRAVSEDGNLTAQAKVNQFFSVRPQFRWRGLGPIPNSALQLRPEYAHRDAELRFKDRLPVKEIDDH
KACQCGDILRGLAKPKDCKVFGRGCNPETPLGSCMVSSEGACNAYYRYQGVDIKEPHHG

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=363, Percent_Identity=44.0771349862259, Blast_Score=337, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41863; Mature: 41863

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELKHLYQGFRDPQTIANLARDIQLTAKTIKQQINIMEVCGGHTHTIMKYGLLDLLPDN
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCC
IEFIHGPGCPVCVMPKERIDQAAALASQENVILVTLGDMIRVPGSQGSLASFRAKGCDIR
CEEEECCCCCEEECCHHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCHHHHHHCCCCCC
PIYDPLDTLKIARDNPDKIVVFFAIGFETSTPMTAILLQLAEHEKLDNLLFHINHVLVPP
CCCCCHHHHEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCC
AIDAVMHDPNARVNAFIGPAHVSVISGAKIYRPAVAQYGTPVVVSGFEPVDVMESILRIV
HHHHHHCCCCCCEEEEECHHHHHHCCCCHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHH
RQKAAGKAELDIQYSRAVSEDGNLTAQAKVNQFFSVRPQFRWRGLGPIPNSALQLRPEYA
HHHCCCCEEEEEEEHHHCCCCCCEEEEEEHHHHHCCCCCCEECCCCCCCCCCEEECHHHH
HRDAELRFKDRLPVKEIDDHKACQCGDILRGLAKPKDCKVFGRGCNPETPLGSCMVSSEG
CCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
ACNAYYRYQGVDIKEPHHG
CCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLELKHLYQGFRDPQTIANLARDIQLTAKTIKQQINIMEVCGGHTHTIMKYGLLDLLPDN
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCC
IEFIHGPGCPVCVMPKERIDQAAALASQENVILVTLGDMIRVPGSQGSLASFRAKGCDIR
CEEEECCCCCEEECCHHHHHHHHHHCCCCCEEEEEECCEEECCCCCCCHHHHHHCCCCCC
PIYDPLDTLKIARDNPDKIVVFFAIGFETSTPMTAILLQLAEHEKLDNLLFHINHVLVPP
CCCCCHHHHEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCC
AIDAVMHDPNARVNAFIGPAHVSVISGAKIYRPAVAQYGTPVVVSGFEPVDVMESILRIV
HHHHHHCCCCCCEEEEECHHHHHHCCCCHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHH
RQKAAGKAELDIQYSRAVSEDGNLTAQAKVNQFFSVRPQFRWRGLGPIPNSALQLRPEYA
HHHCCCCEEEEEEEHHHCCCCCCEEEEEEHHHHHCCCCCCEECCCCCCCCCCEEECHHHH
HRDAELRFKDRLPVKEIDDHKACQCGDILRGLAKPKDCKVFGRGCNPETPLGSCMVSSEG
CCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEECCCC
ACNAYYRYQGVDIKEPHHG
CCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275; 8510650 [H]