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The map label for this gene is yfbQ [C]

Identifier: 120598944

GI number: 120598944

Start: 2459376

End: 2460590

Strand: Direct

Name: yfbQ [C]

Synonym: Sputw3181_2136

Alternate gene names: 120598944

Gene position: 2459376-2460590 (Clockwise)

Preceding gene: 120598941

Following gene: 120598945

Centisome position: 52.23

GC content: 46.17

Gene sequence:

>1215_bases
ATGCGCCCTATCATCAAATCCAACAAACTGGATAGCGTTTGCTATGACATCCGCGGCCCAGTGCACAAGGAAGCCAGACG
TTTAGAAGACGAGGGGCATCGAATCCTCAAACTCAACATTGGTAATCCAGCCCCCTTCGGTTTTGAAGCGCCAGAGGAAA
TTGTGCGCGATGTGATCCTTAATTTACCCAGTGCCCAAGGCTACTGTGAGTCAAAAGGATTATTCTCTGCCCGCAAGGCT
ATCGTGCAGTATTATCAATCCCTAGGGATTTTTGGTGTTGATATCGAAGATATCTATATCGGTAATGGCGTTTCAGAACT
CATTATGATGGCGATGCAAGGTTTGCTGAATACCGACGATGAGATCTTAATCCCCTCACCAGACTATCCTCTGTGGACTG
CGGCAGCCAACCTCGCGGGCGGCAAAGCGGTACATTATCGCTGCGATGAAGAAGCAGACTGGTTCCCCGATCTCAACGAC
ATTAAAAGCAAAATCTCATCACGTACCCGCGGCATAGTGCTGATTAACCCAAACAACCCAACGGGTGCGGTATACAGCAG
AGAATTACTGCTGCAAGTGGTTGAACTGTGCCGTCAACATGATCTGATCCTATTTGCCGATGAAATTTACGACAAAATTT
TATACGATGAAGCCAAACATATTCCTGCTGCAGGTTTATCAGACGATATTTTAACTGTTACGTTTAACGGTCTCTCTAAA
GCTTATCGTGCAGCAGGATTTCGTGTCGGTTGGATGATGTTGTCTGGCAATCTTAAGGCCGCTAAAAGTTACATCGAAGG
CTTAGAAATGCTGTCCTCGATGCGCCTTTGTGCAAACGTGCCCAATCAACATGCGATTCAAACCGCGCTTGGCGGTTACC
AAAGCATTAACGAGCTTATTTTGCCTAATGGCCGCCTTACGGTTCAACGGGATGCTTGTTATGAATTGCTTAACCAAATC
CCCGGCGTGAGCGTGAAAAAACCAAAGGGTGCACTCTATGCCTTCCCCAAATTGGATATGAAAAAATTCAATCTGCGAGA
TGATGAGCGTTTAGTGCTGGATTTACTCAGGGAAAAGAAAATTCTGTTAGTCCATGGTAGCGCCTTTAACTGGCCAGAGC
CCGATCATTTACGAGTGGTTTTCTTACCCTATAAAGAAGATCTCAACAAAGCGCTGACCGAGTTTGGTGACTTCCTCGAA
AACTATCGACAGTAG

Upstream 100 bases:

>100_bases
AAAATGTGCTCATCAAAGCCTTTCCCCCTTCCTTAACCCACTAAATTTCGTTATGGTGCGCTAACTTAAGCCAAAATTTT
ATGCATGTTCCGAGGTGTAA

Downstream 100 bases:

>100_bases
AATATCCCTTTAACGGTTTGAGTCATAAAGCGATCCAAGTGGTCGCTTTATTTTTAGCGATTTCGACAAATCCTCCACGC
CCATGCTCACGTGTCATCCA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLE
NYRQ

Sequences:

>Translated_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLE
NYRQ
>Mature_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLE
NYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=26.8617021276596, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI19263340, Length=473, Percent_Identity=26.215644820296, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=25.5555555555556, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI215599424, Length=382, Percent_Identity=27.2251308900524, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI95147551, Length=266, Percent_Identity=28.1954887218045, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI169881279, Length=266, Percent_Identity=28.1954887218045, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI56713256, Length=340, Percent_Identity=25.8823529411765, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI56713254, Length=340, Percent_Identity=25.8823529411765, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI169881281, Length=147, Percent_Identity=32.6530612244898, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI149944424, Length=378, Percent_Identity=21.957671957672, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=68.5643564356436, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1788722, Length=398, Percent_Identity=25.3768844221106, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1786816, Length=298, Percent_Identity=23.8255033557047, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787909, Length=297, Percent_Identity=20.8754208754209, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=27.5862068965517, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=465, Percent_Identity=24.0860215053763, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=264, Percent_Identity=25.7575757575758, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=264, Percent_Identity=25.7575757575758, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=180, Percent_Identity=29.4444444444444, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=24.5733788395904, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=380, Percent_Identity=26.8421052631579, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=378, Percent_Identity=27.2486772486773, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=24.8945147679325, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=24.3386243386243, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45551451, Length=478, Percent_Identity=24.0585774058577, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=478, Percent_Identity=24.0585774058577, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641760, Length=478, Percent_Identity=24.0585774058577, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641768, Length=478, Percent_Identity=24.0585774058577, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641766, Length=478, Percent_Identity=24.0585774058577, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641764, Length=478, Percent_Identity=24.0585774058577, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573069, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646114, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573067, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573065, Length=329, Percent_Identity=25.531914893617, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45445; Mature: 45445

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHEEEECCCHHHHHHHHHHHHCCCCC
EILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLNDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCC
TGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHC
LPNGRLTVQRDACYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKK
CCCCCEEEEHHHHHHHHHHCCCCCEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHCCC
ILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCHHEEEECCCHHHHHHHHHHHHCCCCC
EILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLNDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCC
TGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHC
LPNGRLTVQRDACYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKK
CCCCCEEEEHHHHHHHHHHCCCCCEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHCCC
ILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]