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The map label for this gene is dgoR [H]

Identifier: 120598763

GI number: 120598763

Start: 2253707

End: 2254423

Strand: Direct

Name: dgoR [H]

Synonym: Sputw3181_1948

Alternate gene names: 120598763

Gene position: 2253707-2254423 (Clockwise)

Preceding gene: 120598762

Following gene: 120598765

Centisome position: 47.87

GC content: 45.47

Gene sequence:

>717_bases
ATGGCAAATCAGGCAAACAACCGACCGCAAAATATCCACAACTGGGTGGCTAGCGAACTGGGTTCTCGTATTGTTGGCGG
TTTTTATGCACCAGGTGAATATATTCCTAATGAAAATACCATCTGTGAAGAACTTGAGGTCTCCCGTACATCGTTAAGGG
AAGCATTTAAGGTGCTGACGGCTAAGGGGCTAATCGAATCTCGGCCGAAACTGGGTACCCGCATTCGTGAGCGTCGTCAT
TGGAACATGTTTGATCCTGTGATCTTAAACTGGTTTTCCCAATCTAAACCGTCGCCAGAGTTTTACACTTCGTTGTATGA
AATTCGTGAGGTGTTTGAGCCAGCCGCCGCAGAATTGGCCGCTAAAAAACGTACGCCAGAGCAGCTTGAAATCATTGAAG
CTGCCTATGCCAAAATGGAAGCCGCACAGCTGGGTACGGATGAGGTATATACCTCAGATATCGAGTTTCATATGGCGATT
CTGGATGCCACTAATAACGAATTTATGGTGTCTTTGGGTGTCTCCATTCAATCGGCATTGCTGGAATTGTTTAGATTAAG
CAGTACGATTCAAGATGATTTTCTACAATCACTTCCGGGTCATAAGGCCATTTATACCGCGATAGCGGCAGGAGACAGCG
TGCGTGCCAAAGCCGAAATGAATAAGCTGCTGTCGACTTCCCAAGAAACATTAAAGAAAAATATTGAGCGAGACTAA

Upstream 100 bases:

>100_bases
TTTAGGGAAAGGTAGTATTATAACATTAGATAAATCTTAGGTTTATCACCTATTCATCTAGATTGAGTTCGGCATATTTT
CTAAGACAAAAGAGGGCGCA

Downstream 100 bases:

>100_bases
TCTGTTTGTTACATAAGGTGATCTTTGCCATTAGATCACCTTTTTGTTTTTCGCTGACATGAGGACTTAAACTGCTATTG
TGACGCTGAAATACCTTCTG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENTICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRH
WNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEIIEAAYAKMEAAQLGTDEVYTSDIEFHMAI
LDATNNEFMVSLGVSIQSALLELFRLSSTIQDDFLQSLPGHKAIYTAIAAGDSVRAKAEMNKLLSTSQETLKKNIERD

Sequences:

>Translated_238_residues
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENTICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRH
WNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEIIEAAYAKMEAAQLGTDEVYTSDIEFHMAI
LDATNNEFMVSLGVSIQSALLELFRLSSTIQDDFLQSLPGHKAIYTAIAAGDSVRAKAEMNKLLSTSQETLKKNIERD
>Mature_237_residues
ANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENTICEELEVSRTSLREAFKVLTAKGLIESRPKLGTRIRERRHW
NMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELAAKKRTPEQLEIIEAAYAKMEAAQLGTDEVYTSDIEFHMAIL
DATNNEFMVSLGVSIQSALLELFRLSSTIQDDFLQSLPGHKAIYTAIAAGDSVRAKAEMNKLLSTSQETLKKNIERD

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=215, Percent_Identity=32.5581395348837, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI48994961, Length=219, Percent_Identity=31.0502283105023, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789353, Length=168, Percent_Identity=30.952380952381, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786303, Length=230, Percent_Identity=27.8260869565217, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790780, Length=242, Percent_Identity=29.3388429752066, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790032, Length=235, Percent_Identity=28.936170212766, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26832; Mature: 26700

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENTICEELEVSRTSLREAFKVLT
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKGLIESRPKLGTRIRERRHWNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELA
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKKRTPEQLEIIEAAYAKMEAAQLGTDEVYTSDIEFHMAILDATNNEFMVSLGVSIQSAL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHEEEEEEECCCCCEEEEECHHHHHHH
LELFRLSSTIQDDFLQSLPGHKAIYTAIAAGDSVRAKAEMNKLLSTSQETLKKNIERD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANQANNRPQNIHNWVASELGSRIVGGFYAPGEYIPNENTICEELEVSRTSLREAFKVLT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AKGLIESRPKLGTRIRERRHWNMFDPVILNWFSQSKPSPEFYTSLYEIREVFEPAAAELA
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AKKRTPEQLEIIEAAYAKMEAAQLGTDEVYTSDIEFHMAILDATNNEFMVSLGVSIQSAL
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHEEEEEEECCCCCEEEEECHHHHHHH
LELFRLSSTIQDDFLQSLPGHKAIYTAIAAGDSVRAKAEMNKLLSTSQETLKKNIERD
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]