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The map label for this gene is fadH [H]

Identifier: 120598750

GI number: 120598750

Start: 2235790

End: 2237808

Strand: Direct

Name: fadH [H]

Synonym: Sputw3181_1935

Alternate gene names: 120598750

Gene position: 2235790-2237808 (Clockwise)

Preceding gene: 120598747

Following gene: 120598751

Centisome position: 47.49

GC content: 47.55

Gene sequence:

>2019_bases
ATGTCGTTTCCCCATTTATTAGAACCCTTAGATCTGGGATTTACCCAGCTCAAAAACCGCGTGCTTATGGGCTCAATGCA
CACAGGTTTAGAAGAAGAAAAGGGCGGATTTGAGAAACTGGCAGCGTTTTACAAAGAACGCGCTCTGGGCGGTGTAGGTT
TGATTGTGACGGGCGGTATTTCCCCCAATCTTCGTGGCCGCCTTACGCCCCATGCTTGTCAGTTGAGTTTTCCATGGCAA
GTGGGTAAGCATCGCGTGGTTACGCAGGCGGTGCATGAGGCTGGCGGTAAGATTTGTATGCAAATTTTGCATGCGGGTCG
TTATGGTTATCATCCTTTTTCCCAAGCACCAAGCAAGATTAAGTCACCCATTACACCCTTTACGCCGTCGGCAATGTCGA
GCCGGCAAGTACGTTCGACCATTAAGGATTACGCCAGCTCTGCCGCCCTTGCTAAAAAAGCGGGTTACGATGGTGTTGAG
GTGATGGGCTCTGAAGGGTATTTAATTAATCAGTTTGTCAGTGCGCGTACCAATACTCGCAGCGATGAATGGGGCGGTGC
GTTTGAAAAACGAGCGCAATTTCCTATTGAGATTGTTAACGCGATACGGGCAAAAGTCGGTAAAGAATTCATCATTATCT
TCCGGTTATCCATGCTCGATCTGGTCGATAACGGCTCGACTTGGGATGAAGTGGTGCAACTCGCCCAGTGGCTTGAGCAA
GCGGGGGTGTCTATTATCAATACGGGGATTGGTTGGCATGAAGCGCGTATACCAACAATCGCAACCAGTGTGCCGCGGGG
CGCCTTTGCATGGGTGACTGAAAAACTCAAACAATCCGTTTCTGTCCCCTTAATTGCAACTAACCGTATTAATACGCCGG
AGATTGGCGAACAAATCATCGCCTCAGGGCAAGCGGATATGGTGTCGATGGCAAGACCTTTCCTTGCCGATCCCGAGTTT
GTGAATAAGGCTGCGGCGAACACACCGGAGCTTATCAACACCTGCATTGGCTGTAACCAAGCTTGTCTTGACCATACTTT
TTCCCTCAAGCGCGCGACCTGCTTAGTGAATCCTCGTGCCTGTTATGAGACTGAAATCAACTTCTTACCTACAGCAAATA
AAAAACGTATCGCTGTGATGGGCGCAGGTCCTGCGGGCATGGCATTTTCTGTTTATGCCGCCATGCGTGGCCATGAAGTT
GTCTTGTTTGAAGCTAAATCTGAAGTAGGCGGTCAATTTAATCTGGCACGTAAAATCCCAGGAAAAGAAGAATTTAACGA
GACTATTCGTTATTTCCTCAATCAAATCAAACTGTATAAAATCGATTTGCGGTTAAATACTCGGTTAGATGCCAAGGTGT
TAGAAACGGAGACGTTTGATGAAATCGTTATCGCATCAGGCGTGGTACCCAGAGCATTAAACTTCCCCGGATTTGACAGC
CATAAAGTGGTGGATTATCAACAAGTGCTCACAGGCCAAGTCAGTATTGGCGATAAAGTCGCCTTAATTGGTGCCGGCGG
TATTGGTTTTGATATGGCGCATTACCTATGTGAATCCGAATCGAGCACATTACATCCTGACAAATGGTTAAAACAGTGGG
GCATTGATAAGCAATATCAACATGCGGGCGGTTTAAGTGAGCCTGAGACCGATAATCCAGAACACAGACAAGTCTATTTA
TTGCAACGCAAAACCTCAAAAATGGGCCAAGGCTTAGGTAAAACGACTGGCTGGATCCACCGCTTAGTGTTAAAGCAACA
TGATGTGAAGATGAAAACGGGTGTGAGCTACAACAAGTTTGATGATGAAGGATTGCATATTCGCGTTGGCGAGCAAGCAG
AAGTGTTGCCCGTCGATAATGTTATCCTCTGCGCTGGCCAAGAATCTAATCGCACGTTAGTGGATGAGATGAAAGCAACA
GGCATTCCTGTGCATTTAATCGGCGGTGTAGATGTTGCTGCAGAACTTGATGCGAAACGGGCTATTCGCCAAGGTGCCGA
ACTGGCGATGCGGTTATAG

Upstream 100 bases:

>100_bases
ATTGTAAAGGTTTTTAACTTAAGGCATCTAAGCAACGGTTGAGCTTATATTTGAGTCAAGGTATGCTGATTTAAATCACT
TGTTTTAAAAGGATGTTTGA

Downstream 100 bases:

>100_bases
AGCCATTTTGAAGAACCCATATAAAATTAAAGCCTGAATCTTAATCAGGCTTTTTTTATTGTATTTTCAACATTGTTGCC
GCAAATACGCTAAGGTTTAA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVE
VMGSEGYLINQFVSARTNTRSDEWGGAFEKRAQFPIEIVNAIRAKVGKEFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
AGVSIINTGIGWHEARIPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHEV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLYKIDLRLNTRLDAKVLETETFDEIVIASGVVPRALNFPGFDS
HKVVDYQQVLTGQVSIGDKVALIGAGGIGFDMAHYLCESESSTLHPDKWLKQWGIDKQYQHAGGLSEPETDNPEHRQVYL
LQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVSYNKFDDEGLHIRVGEQAEVLPVDNVILCAGQESNRTLVDEMKAT
GIPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Sequences:

>Translated_672_residues
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQ
VGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVE
VMGSEGYLINQFVSARTNTRSDEWGGAFEKRAQFPIEIVNAIRAKVGKEFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
AGVSIINTGIGWHEARIPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEF
VNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHEV
VLFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLYKIDLRLNTRLDAKVLETETFDEIVIASGVVPRALNFPGFDS
HKVVDYQQVLTGQVSIGDKVALIGAGGIGFDMAHYLCESESSTLHPDKWLKQWGIDKQYQHAGGLSEPETDNPEHRQVYL
LQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVSYNKFDDEGLHIRVGEQAEVLPVDNVILCAGQESNRTLVDEMKAT
GIPVHLIGGVDVAAELDAKRAIRQGAELAMRL
>Mature_671_residues
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGISPNLRGRLTPHACQLSFPWQV
GKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKIKSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEV
MGSEGYLINQFVSARTNTRSDEWGGAFEKRAQFPIEIVNAIRAKVGKEFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQA
GVSIINTGIGWHEARIPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQIIASGQADMVSMARPFLADPEFV
NKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRACYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHEVV
LFEAKSEVGGQFNLARKIPGKEEFNETIRYFLNQIKLYKIDLRLNTRLDAKVLETETFDEIVIASGVVPRALNFPGFDSH
KVVDYQQVLTGQVSIGDKVALIGAGGIGFDMAHYLCESESSTLHPDKWLKQWGIDKQYQHAGGLSEPETDNPEHRQVYLL
QRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVSYNKFDDEGLHIRVGEQAEVLPVDNVILCAGQESNRTLVDEMKATG
IPVHLIGGVDVAAELDAKRAIRQGAELAMRL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=674, Percent_Identity=56.973293768546, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=26.9340974212034, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=251, Percent_Identity=25.8964143426295, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=224, Percent_Identity=26.3392857142857, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=175, Percent_Identity=30.2857142857143, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=26, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=248, Percent_Identity=24.1935483870968, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=345, Percent_Identity=23.768115942029, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=251, Percent_Identity=24.7011952191235, Blast_Score=79, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=29.0598290598291, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=356, Percent_Identity=23.0337078651685, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73811; Mature: 73679

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEVMGSEGYLINQFVSARTNTR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
SDEWGGAFEKRAQFPIEIVNAIRAKVGKEFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVSIINTGIGWHEARIPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCH
CYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHEVVLFEAKSEVGGQFNLARKIP
HHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLYKIDLRLNTRLDAKVLETETFDEIVIASGVVPRALNFPGFDS
CHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
HKVVDYQQVLTGQVSIGDKVALIGAGGIGFDMAHYLCESESSTLHPDKWLKQWGIDKQYQ
CCEECHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
HAGGLSEPETDNPEHRQVYLLQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVSYNKF
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCC
DDEGLHIRVGEQAEVLPVDNVILCAGQESNRTLVDEMKATGIPVHLIGGVDVAAELDAKR
CCCCCEEEECCCCCEEECCCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC
>Mature Secondary Structure 
SFPHLLEPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYKERALGGVGLIVTGGI
CCCCCCCHHHCCHHHHHCHHEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLTPHACQLSFPWQVGKHRVVTQAVHEAGGKICMQILHAGRYGYHPFSQAPSKI
CCCCCCCCCCCEEEEECCHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHCCHHH
KSPITPFTPSAMSSRQVRSTIKDYASSAALAKKAGYDGVEVMGSEGYLINQFVSARTNTR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
SDEWGGAFEKRAQFPIEIVNAIRAKVGKEFIIIFRLSMLDLVDNGSTWDEVVQLAQWLEQ
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHH
AGVSIINTGIGWHEARIPTIATSVPRGAFAWVTEKLKQSVSVPLIATNRINTPEIGEQII
CCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHH
ASGQADMVSMARPFLADPEFVNKAAANTPELINTCIGCNQACLDHTFSLKRATCLVNPRA
HCCCHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEEECCCH
CYETEINFLPTANKKRIAVMGAGPAGMAFSVYAAMRGHEVVLFEAKSEVGGQFNLARKIP
HHCCCCCEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHCCC
GKEEFNETIRYFLNQIKLYKIDLRLNTRLDAKVLETETFDEIVIASGVVPRALNFPGFDS
CHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCCCCC
HKVVDYQQVLTGQVSIGDKVALIGAGGIGFDMAHYLCESESSTLHPDKWLKQWGIDKQYQ
CCEECHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
HAGGLSEPETDNPEHRQVYLLQRKTSKMGQGLGKTTGWIHRLVLKQHDVKMKTGVSYNKF
HCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHCCCCCCCC
DDEGLHIRVGEQAEVLPVDNVILCAGQESNRTLVDEMKATGIPVHLIGGVDVAAELDAKR
CCCCCEEEECCCCCEEECCCEEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHHH
AIRQGAELAMRL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]