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The map label for this gene is qseC [H]

Identifier: 120598745

GI number: 120598745

Start: 2226766

End: 2228160

Strand: Direct

Name: qseC [H]

Synonym: Sputw3181_1930

Alternate gene names: 120598745

Gene position: 2226766-2228160 (Clockwise)

Preceding gene: 120598744

Following gene: 120598746

Centisome position: 47.29

GC content: 41.58

Gene sequence:

>1395_bases
GTGAACCGATTAAAGAAGCTGAACACGTATTCACTACGTTTATTGCTGACGCTGTTGATGCTTTCGGGAATTTCCGTTTC
AGTGGGGATTTCTAGCTGGTTCAGTATTCTAGATGCAAAATATCAAATCGAAGAATTATTTGATGCGCAAATGTTGCAAA
CCGCTAAAATACTAGAGCTTTTCTATCATGATGAGGTTGATGCTCACCAGCCAAACCCTACACCTCAAGTCCTCCATATT
CCCGATAGTCAAGTGAGTACCTTTACTGAAAAATCGGACGCTTTAGAGCTTGCTTATGAACATAAACTGGCTTTTCAGAT
CTGGAATGAGGCAAAGCAAATACTAGTCCTATCGGACAATATTGGTCGCCAGCCTATCACTGAGTTTGAGCAGGGATACC
ACAAAACCTTATTAGGCGGTGAGCTTTGGCACGTTTTTAGTTTTTTTTCTACAAAATATCGAGTGTGGATTATCACTGCT
CAGCAGGATGAGGTACGTGAGGAGCTTGTCTCACAGATTATGCACAATACGGTCATTGTGCCTTTAATTGTTGTGCCATT
AACATTATTGATCGTGAGTTTATTGTTTTATATTGCATTTAAGCCATTAAAAATATTTGAGAAAGAATTAATCCAGCGTG
CGCCTAACGATCTGACCCCCTTGACGATGTCATTACCCAAAGAGCTTATTCCTGTACGCAATGCACTTAACCAGTACATT
AGAAGCATTGCGCGTTTTATTGCGAGGGAACGCCGCTTTAGTGCCGATGCAGCCCATGAGCTTAAAACCCCGTTATCTGT
GATCAAATTACATCAACATGGCTTAGAGAGTCTTATCGGAGATGATCCGCAGCAGCGGTTTCATTTAGCGGCGATTGATG
CTGGTGTTGTACATATGAGCCATACAGTAGAACAACTACTAGTGCTTGCACGGGTTGACTCGATCGATGAATTGAATGTG
CAATCCCATGCCATTTTATCCATAGTGGAAGATGCATTAAATCAGTTAATGCCGCAAATAACAGATTATGAGTGGAATAT
TCAAATCGACCCCAACTTAACCTTAAAATGTGATCGATTTTATTTACTGCTAGTCCTGAAAAATATCATTGAAAATGCGT
GTAAATACAGCCCGATAGAAACTGAGATTTCAATTTTTGCAGATTCAGTACCGTCAGGTATTGAGATCCGTGTCGCTGAT
CGTGGACAGGGGATGACAATAGAACAAATTGCCAGTGCAACAGAGCGTTTTTATCGTGTGAATGAAAATGAAGGCATAGG
TGCAGGGCTTGGGTTATCCATCTGCCACCACATTGTAGAGTTGCATCAAGGACGGCTTGAGATAAGACCTCGGGAGCAGG
GAGGGTTAGTGGTTATCCTTTTTTTACCTCAATAG

Upstream 100 bases:

>100_bases
TTGGTTATACCCTGATTGAAATGCACTAACTAGAGTAATAGCGTGATATACCTCAGTTTATAGTATGTAGTTGGCAATTT
GAGAGAATGAGAATTTCACC

Downstream 100 bases:

>100_bases
GGCATGTTTTGCGGCTTCCATTGTTATCACTCTCTCTTGTGTCGCCCTGTGCAGAGATTATGGCGGTACTCAGCTAGAAT
ATTCTCAACTATAGCAATCA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNRLKKLNTYSLRLLLTLLMLSGISVSVGISSWFSILDAKYQIEELFDAQMLQTAKILELFYHDEVDAHQPNPTPQVLHI
PDSQVSTFTEKSDALELAYEHKLAFQIWNEAKQILVLSDNIGRQPITEFEQGYHKTLLGGELWHVFSFFSTKYRVWIITA
QQDEVREELVSQIMHNTVIVPLIVVPLTLLIVSLLFYIAFKPLKIFEKELIQRAPNDLTPLTMSLPKELIPVRNALNQYI
RSIARFIARERRFSADAAHELKTPLSVIKLHQHGLESLIGDDPQQRFHLAAIDAGVVHMSHTVEQLLVLARVDSIDELNV
QSHAILSIVEDALNQLMPQITDYEWNIQIDPNLTLKCDRFYLLLVLKNIIENACKYSPIETEISIFADSVPSGIEIRVAD
RGQGMTIEQIASATERFYRVNENEGIGAGLGLSICHHIVELHQGRLEIRPREQGGLVVILFLPQ

Sequences:

>Translated_464_residues
MNRLKKLNTYSLRLLLTLLMLSGISVSVGISSWFSILDAKYQIEELFDAQMLQTAKILELFYHDEVDAHQPNPTPQVLHI
PDSQVSTFTEKSDALELAYEHKLAFQIWNEAKQILVLSDNIGRQPITEFEQGYHKTLLGGELWHVFSFFSTKYRVWIITA
QQDEVREELVSQIMHNTVIVPLIVVPLTLLIVSLLFYIAFKPLKIFEKELIQRAPNDLTPLTMSLPKELIPVRNALNQYI
RSIARFIARERRFSADAAHELKTPLSVIKLHQHGLESLIGDDPQQRFHLAAIDAGVVHMSHTVEQLLVLARVDSIDELNV
QSHAILSIVEDALNQLMPQITDYEWNIQIDPNLTLKCDRFYLLLVLKNIIENACKYSPIETEISIFADSVPSGIEIRVAD
RGQGMTIEQIASATERFYRVNENEGIGAGLGLSICHHIVELHQGRLEIRPREQGGLVVILFLPQ
>Mature_464_residues
MNRLKKLNTYSLRLLLTLLMLSGISVSVGISSWFSILDAKYQIEELFDAQMLQTAKILELFYHDEVDAHQPNPTPQVLHI
PDSQVSTFTEKSDALELAYEHKLAFQIWNEAKQILVLSDNIGRQPITEFEQGYHKTLLGGELWHVFSFFSTKYRVWIITA
QQDEVREELVSQIMHNTVIVPLIVVPLTLLIVSLLFYIAFKPLKIFEKELIQRAPNDLTPLTMSLPKELIPVRNALNQYI
RSIARFIARERRFSADAAHELKTPLSVIKLHQHGLESLIGDDPQQRFHLAAIDAGVVHMSHTVEQLLVLARVDSIDELNV
QSHAILSIVEDALNQLMPQITDYEWNIQIDPNLTLKCDRFYLLLVLKNIIENACKYSPIETEISIFADSVPSGIEIRVAD
RGQGMTIEQIASATERFYRVNENEGIGAGLGLSICHHIVELHQGRLEIRPREQGGLVVILFLPQ

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=471, Percent_Identity=31.4225053078556, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=31.986531986532, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=29.6943231441048, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=27.5510204081633, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=27.734375, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786912, Length=211, Percent_Identity=30.3317535545024, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=316, Percent_Identity=23.1012658227848, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=300, Percent_Identity=22.6666666666667, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52832; Mature: 52832

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLKKLNTYSLRLLLTLLMLSGISVSVGISSWFSILDAKYQIEELFDAQMLQTAKILEL
CCCHHHCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYHDEVDAHQPNPTPQVLHIPDSQVSTFTEKSDALELAYEHKLAFQIWNEAKQILVLSDN
HHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
IGRQPITEFEQGYHKTLLGGELWHVFSFFSTKYRVWIITAQQDEVREELVSQIMHNTVIV
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
PLIVVPLTLLIVSLLFYIAFKPLKIFEKELIQRAPNDLTPLTMSLPKELIPVRNALNQYI
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHH
RSIARFIARERRFSADAAHELKTPLSVIKLHQHGLESLIGDDPQQRFHLAAIDAGVVHMS
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHHHHH
HTVEQLLVLARVDSIDELNVQSHAILSIVEDALNQLMPQITDYEWNIQIDPNLTLKCDRF
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHH
YLLLVLKNIIENACKYSPIETEISIFADSVPSGIEIRVADRGQGMTIEQIASATERFYRV
HHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHEEC
NENEGIGAGLGLSICHHIVELHQGRLEIRPREQGGLVVILFLPQ
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MNRLKKLNTYSLRLLLTLLMLSGISVSVGISSWFSILDAKYQIEELFDAQMLQTAKILEL
CCCHHHCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYHDEVDAHQPNPTPQVLHIPDSQVSTFTEKSDALELAYEHKLAFQIWNEAKQILVLSDN
HHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
IGRQPITEFEQGYHKTLLGGELWHVFSFFSTKYRVWIITAQQDEVREELVSQIMHNTVIV
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHH
PLIVVPLTLLIVSLLFYIAFKPLKIFEKELIQRAPNDLTPLTMSLPKELIPVRNALNQYI
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHH
RSIARFIARERRFSADAAHELKTPLSVIKLHQHGLESLIGDDPQQRFHLAAIDAGVVHMS
HHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHEEEEEHHHHHHHHH
HTVEQLLVLARVDSIDELNVQSHAILSIVEDALNQLMPQITDYEWNIQIDPNLTLKCDRF
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEHHH
YLLLVLKNIIENACKYSPIETEISIFADSVPSGIEIRVADRGQGMTIEQIASATERFYRV
HHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHEEC
NENEGIGAGLGLSICHHIVELHQGRLEIRPREQGGLVVILFLPQ
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]