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The map label for this gene is hscB

Identifier: 120598680

GI number: 120598680

Start: 2147742

End: 2148266

Strand: Direct

Name: hscB

Synonym: Sputw3181_1865

Alternate gene names: 120598680

Gene position: 2147742-2148266 (Clockwise)

Preceding gene: 120598679

Following gene: 120598681

Centisome position: 45.62

GC content: 43.43

Gene sequence:

>525_bases
ATGAATTATTTCGAGCTGTTTAAATTTTCTCCTGCCTTCGATATAGACACCGCTGTGCTTGCAGAACGCTATCGCGAATT
GCAGCGGGCGGTGCATCCCGATAAGTTTGCCCATGATACTGAGCAGCAGAAGTTGTTGTCTGTGCAGCGCACAGCACAAG
TGAATGATGGTTATCAAACCTTAAAAGACCCCATTCGTCGTGCTGAGCATCTGTTGTCACTGCGCGGTATTGATCTAAGC
CATGAAACCACCACAGTCAAAGATACTGTTTTTTTGATGCAGCAAATGGAGTGGCGTGAGGCTTTAGAAGATATCCGTCA
CAGCACTGATCCTCAAGAGAGTATTGATGAGTTATATCAATCCTTTGCCGAGTATCGTGCCAAACTTACTTATATGTTGA
CTGCACAACTTAACAGTAGCAAAGATGAAGATGCTTTGTTAGCGGCAGATCAAGTTCGCAAGCTCAAGTTTATGGCAAAA
TTGCATGATGAGCTGACAAGAATTGAAGATGCTCTGTTAGATTAA

Upstream 100 bases:

>100_bases
AAAGAAGGGCTCAATGAAGGCTTCCAATTTAACAATCCTAACGCAAAAGGTGAGTGTGGTTGTGGTGAGAGTTTCACTGT
TTAACCGCTAAAGTTGACGC

Downstream 100 bases:

>100_bases
TTTTCCGTGTTTATGTGATTCAGCCAACTTCATTTTTTTTGGGGTTGGCGTTACTAAGTTGGATATATATGGCCCTTTTG
CAGATAGCTGAGCCCGGTCA

Product: co-chaperone HscB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFAHDTEQQKLLSVQRTAQVNDGYQTLKDPIRRAEHLLSLRGIDLS
HETTTVKDTVFLMQQMEWREALEDIRHSTDPQESIDELYQSFAEYRAKLTYMLTAQLNSSKDEDALLAADQVRKLKFMAK
LHDELTRIEDALLD

Sequences:

>Translated_174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFAHDTEQQKLLSVQRTAQVNDGYQTLKDPIRRAEHLLSLRGIDLS
HETTTVKDTVFLMQQMEWREALEDIRHSTDPQESIDELYQSFAEYRAKLTYMLTAQLNSSKDEDALLAADQVRKLKFMAK
LHDELTRIEDALLD
>Mature_174_residues
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFAHDTEQQKLLSVQRTAQVNDGYQTLKDPIRRAEHLLSLRGIDLS
HETTTVKDTVFLMQQMEWREALEDIRHSTDPQESIDELYQSFAEYRAKLTYMLTAQLNSSKDEDALLAADQVRKLKFMAK
LHDELTRIEDALLD

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI50301234, Length=101, Percent_Identity=40.5940594059406, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1788876, Length=176, Percent_Identity=42.0454545454545, Blast_Score=125, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161084223, Length=104, Percent_Identity=34.6153846153846, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 20381; Mature: 20381

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFAHDTEQQKLLSVQRTAQVNDGYQT
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCHHH
LKDPIRRAEHLLSLRGIDLSHETTTVKDTVFLMQQMEWREALEDIRHSTDPQESIDELYQ
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SFAEYRAKLTYMLTAQLNSSKDEDALLAADQVRKLKFMAKLHDELTRIEDALLD
HHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFAHDTEQQKLLSVQRTAQVNDGYQT
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCHHH
LKDPIRRAEHLLSLRGIDLSHETTTVKDTVFLMQQMEWREALEDIRHSTDPQESIDELYQ
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SFAEYRAKLTYMLTAQLNSSKDEDALLAADQVRKLKFMAKLHDELTRIEDALLD
HHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA