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The map label for this gene is yeeO [C]

Identifier: 120598545

GI number: 120598545

Start: 1986550

End: 1988145

Strand: Direct

Name: yeeO [C]

Synonym: Sputw3181_1728

Alternate gene names: 120598545

Gene position: 1986550-1988145 (Clockwise)

Preceding gene: 120598544

Following gene: 120598547

Centisome position: 42.19

GC content: 45.68

Gene sequence:

>1596_bases
ATGACACAGGCAAAGTTCGTTGAAGGCCCGATTCTTAGGCATATTTTAGTCATGAGTTCGACTGCTGCGGTGGGGATTTC
AGCCCTATTTGTGGTTGATTTAATCGATATCTTTTTCCTAAGTTTGCTTGGTGAACATGAGCTTGCTGCTGCGGTCGGTT
ATGCGGGCAGTATTTCATTTTTTACCACATCCATCGGGATAGGTTTATCCATTGCCCTCGGTGCGTTAGTTTCGCGTTCC
ATCGGTGCTAAGGATGTGTTACTGGCGAAGCGATTATTGCTTAATAGTGCCGTTGTCACGACCCTTATAAGTGTATTAGT
TAGCGTAGTCGTCACCCTCTTTATTCCTGAACTCGTCGCTCTTGTTGGGGCGAATGGTTATACGGCCGAGCTTGCTGAAA
GTTATTTGTATATCCTTGTGCCCTCACTGCCTTTTATATGTCTTGCAATGGCACTTGGTGGCGCGCTTCGGGCCGTGGGT
GATGCTAAGTTGTCAATGATGTCGACCTTAGCGGGCGGTGGCGTCAATGCGGTACTGGATCCGATTTTTATCTTCCTGTT
TGCGATGGGAATTGAAGGCGCTGCGCTGGCATCTGTGTTGGCACGTATCGCAGTGTTTATCATTGCGGGCAGAGGCGTGG
TGGTAAAACATCAGCTCTTAGGTCAATTTGATTTATCCCATTTTATGGCCGATCTTAGGCCTATATTTGCCATTGCAGGC
CCAGCGATGATGACAAATATTGCCACGCCTATTGGTAATGCTTTTGTAACCCGAGCGATAGCCGATTTTGGCGATGCCTA
TGTGGCAGGGTGGGCCGTATTAGGCCGACTTGTTCCCGTTGCATTTGGGATGATTTTTGCCTTATCTGGAGCCATTGGTC
CCATTGTTGGGCAAAATTTTGGCGCAGGACAATTCGAGCGAGTGCGTGAGAGCCTGACGAAGGCTATTCAGTTTTGTACT
TTGTATGTACTTTCCGTGTCTCTGTTATTATTTCTTTTGAAATCCCAAGTCGTTAGCGTGTTTGACATGAAGGGAGATAG
CGCAGAGTTAATCGAGTTTTTCTGCAGTTATATTGCTGTTTTTTTTACCTTCTCAGGTGTTTTATTTGTGGCAAATGCTT
CATTTAATAATCTTGGTAAAGCAAAATACTCAACGCTATTTAATGTAGGCAAGGCGACTTTAGGCACAATTCCCTTTGTT
TATTTTGGGGCGCTTTGGGGCGGCGTATATGGTGTGTTGATTGGCCAAGTTATCGGTTCTATTTTATTTGGGGTTTTAGG
TGTGCTGGTGGCCTACCGTTTAGTCGACAAAGTAGCTGCCCAAGCTAAGGCTGGCGTTTTACCTGTAAACGCCGAGGCGA
TTAGTACGCCCTTAAACTCTGAACAAGTATTACTTACTGATGAGGACGAGATTGCCAATTGTGTCGCTGAGAACTTACCG
AGTGCCACAAACCCTTTGTCTTCTTCCCATGTACAAATGGGACAAATGACTGAAGAACAGGAATGCCAGTCCATATTAAC
GAGTGACGATGTTAACAAACCGGATAAAGTAGAAGGGACCAAGGATAACCGAACCAAATCTAAAGTGGGTGAGTGA

Upstream 100 bases:

>100_bases
CCGTTGTGGTTGTGAGCTTGATTTGCTTGACTCTTCAACGGCAAAGAACGCAACTTAATATGGTCGCTAAATATTTTTAT
TCTGCAGGTGCACCTCAGCT

Downstream 100 bases:

>100_bases
TACCTTTGACGAATCGTTTCGTTATCATCTGGAAAACTATCCCTAAAATAAAACGCCACAATCAATGTGGCGTTTTATTT
GTGATCTTGAGTGATTATTT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTQAKFVEGPILRHILVMSSTAAVGISALFVVDLIDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRS
IGAKDVLLAKRLLLNSAVVTTLISVLVSVVVTLFIPELVALVGANGYTAELAESYLYILVPSLPFICLAMALGGALRAVG
DAKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGQFDLSHFMADLRPIFAIAG
PAMMTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLVPVAFGMIFALSGAIGPIVGQNFGAGQFERVRESLTKAIQFCT
LYVLSVSLLLFLLKSQVVSVFDMKGDSAELIEFFCSYIAVFFTFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGALWGGVYGVLIGQVIGSILFGVLGVLVAYRLVDKVAAQAKAGVLPVNAEAISTPLNSEQVLLTDEDEIANCVAENLP
SATNPLSSSHVQMGQMTEEQECQSILTSDDVNKPDKVEGTKDNRTKSKVGE

Sequences:

>Translated_531_residues
MTQAKFVEGPILRHILVMSSTAAVGISALFVVDLIDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRS
IGAKDVLLAKRLLLNSAVVTTLISVLVSVVVTLFIPELVALVGANGYTAELAESYLYILVPSLPFICLAMALGGALRAVG
DAKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGQFDLSHFMADLRPIFAIAG
PAMMTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLVPVAFGMIFALSGAIGPIVGQNFGAGQFERVRESLTKAIQFCT
LYVLSVSLLLFLLKSQVVSVFDMKGDSAELIEFFCSYIAVFFTFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFV
YFGALWGGVYGVLIGQVIGSILFGVLGVLVAYRLVDKVAAQAKAGVLPVNAEAISTPLNSEQVLLTDEDEIANCVAENLP
SATNPLSSSHVQMGQMTEEQECQSILTSDDVNKPDKVEGTKDNRTKSKVGE
>Mature_530_residues
TQAKFVEGPILRHILVMSSTAAVGISALFVVDLIDIFFLSLLGEHELAAAVGYAGSISFFTTSIGIGLSIALGALVSRSI
GAKDVLLAKRLLLNSAVVTTLISVLVSVVVTLFIPELVALVGANGYTAELAESYLYILVPSLPFICLAMALGGALRAVGD
AKLSMMSTLAGGGVNAVLDPIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGQFDLSHFMADLRPIFAIAGP
AMMTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLVPVAFGMIFALSGAIGPIVGQNFGAGQFERVRESLTKAIQFCTL
YVLSVSLLLFLLKSQVVSVFDMKGDSAELIEFFCSYIAVFFTFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFVY
FGALWGGVYGVLIGQVIGSILFGVLGVLVAYRLVDKVAAQAKAGVLPVNAEAISTPLNSEQVLLTDEDEIANCVAENLPS
ATNPLSSSHVQMGQMTEEQECQSILTSDDVNKPDKVEGTKDNRTKSKVGE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Homo sapiens, GI22907060, Length=532, Percent_Identity=23.3082706766917, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 55795; Mature: 55664

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAKFVEGPILRHILVMSSTAAVGISALFVVDLIDIFFLSLLGEHELAAAVGYAGSISF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH
FTTSIGIGLSIALGALVSRSIGAKDVLLAKRLLLNSAVVTTLISVLVSVVVTLFIPELVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGANGYTAELAESYLYILVPSLPFICLAMALGGALRAVGDAKLSMMSTLAGGGVNAVLD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PIFIFLFAMGIEGAALASVLARIAVFIIAGRGVVVKHQLLGQFDLSHFMADLRPIFAIAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAMMTNIATPIGNAFVTRAIADFGDAYVAGWAVLGRLVPVAFGMIFALSGAIGPIVGQNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GAGQFERVRESLTKAIQFCTLYVLSVSLLLFLLKSQVVSVFDMKGDSAELIEFFCSYIAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FFTFSGVLFVANASFNNLGKAKYSTLFNVGKATLGTIPFVYFGALWGGVYGVLIGQVIGS
HHHHHCHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILFGVLGVLVAYRLVDKVAAQAKAGVLPVNAEAISTPLNSEQVLLTDEDEIANCVAENLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHCC
SATNPLSSSHVQMGQMTEEQECQSILTSDDVNKPDKVEGTKDNRTKSKVGE
CCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
TQAKFVEGPILRHILVMSSTAAVGISALFVVDLIDIFFLSLLGEHELAAAVGYAGSISF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH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CCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]