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The map label for this gene is sohB [H]

Identifier: 120598431

GI number: 120598431

Start: 1840381

End: 1841397

Strand: Direct

Name: sohB [H]

Synonym: Sputw3181_1614

Alternate gene names: 120598431

Gene position: 1840381-1841397 (Clockwise)

Preceding gene: 120598430

Following gene: 120598434

Centisome position: 39.09

GC content: 41.49

Gene sequence:

>1017_bases
TTGGAATTTTTATACGAATATGGCATGTTTCTGGCGAAAGCTATCACTATAGTGGTCGCAATTGTGGCCGTTATTATTGT
GGTATTGGCTTCGACTGTGAAACATAAATCAGATAAGGGCGAGTTGAGGATTACCAACTTATCTGAAGAGTTAGAAGAGC
TTAAACATGGCTTAAAAGAAGAATTACTCTCAAAAAAAGAATTCAAAGCCTATGAAAAACAGCTAAAAATAGATGAAAAG
GTCAAGGACAAAACAGAGGGGGATACCAGTAAAGGTAAGGTTTTTGTTATTGATTTTAAGGGCAGTATCGATGCAGCTGA
GGTTGCTTCACTGCGTGAAGAAATCAGTGCCATTTTAGCCATTGCCGAAAAAGGTGATGAAGTCGTTGTTAATGTTGAGA
GTGGTGGTGGAATGGTCCATGGCTATGGTTTAGCCTCTAGCCAGTTAGATCGTTTACGTCAAGCCGATATCCCGCTAACG
GTCTGTGTTGATAAAGTCGCTGCCAGTGGTGGTTATATGATGGCTTGCGTAGCAAATAAAATTTATGCCGCGCCTTTTGC
TATCGTCGGTTCCATTGGTGTTGTTGCTCAATTGCCGAACTTTAATCGTTTACTGAAAAAACATGAAATTGACTATGAGC
AGCATACGGCTGGCGATTTCAAACGGACGTTAACGGTTTTTGGTGAAAACACCGATGAGGGAAGGCAGAAGTTCCAAGAG
GAACTCGAAGAAACCCATGTGTTGTTCAAAGCCTTTGTGAGTAAATATCGCCCCGAACTGAATTTGGAGAAGGTGGCAAC
GGGTGAGCATTGGTATGGTCAGCAGGCCATTGAACTCGGACTTGTTGATGAAATTCTGACGAGTGATGATGTTGTCATGT
CGCTGGCGAAAGATCGCAAAGTGTATAAGTTGCGTTATCAAGTGAAGAAAAAGTTGGCAGATAAGATTGCCCATGGAGCC
TCTTTATCTGTTAATGCGATTTTTAATCGTCTTATCGAAAAAAATCGTCCAATGTAA

Upstream 100 bases:

>100_bases
AGCTCACGCTGGGTTTTTTTATGGGCCTTTAGGCTGTTAGAATAGCCCGCAATAAATTAAGTGAAGAGATACGCAAACCT
GCGTCCCAACGGAGAACACT

Downstream 100 bases:

>100_bases
TCTCGATAATAACCTTCTGATTTTATAACCATTAAAACGCCTGCAAATGCAGGCGTTTTGGTTTAGTGAGCTTATTGTGT
TACATAGAAGACGTTAGATT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEFLYEYGMFLAKAITIVVAIVAVIIVVLASTVKHKSDKGELRITNLSEELEELKHGLKEELLSKKEFKAYEKQLKIDEK
VKDKTEGDTSKGKVFVIDFKGSIDAAEVASLREEISAILAIAEKGDEVVVNVESGGGMVHGYGLASSQLDRLRQADIPLT
VCVDKVAASGGYMMACVANKIYAAPFAIVGSIGVVAQLPNFNRLLKKHEIDYEQHTAGDFKRTLTVFGENTDEGRQKFQE
ELEETHVLFKAFVSKYRPELNLEKVATGEHWYGQQAIELGLVDEILTSDDVVMSLAKDRKVYKLRYQVKKKLADKIAHGA
SLSVNAIFNRLIEKNRPM

Sequences:

>Translated_338_residues
MEFLYEYGMFLAKAITIVVAIVAVIIVVLASTVKHKSDKGELRITNLSEELEELKHGLKEELLSKKEFKAYEKQLKIDEK
VKDKTEGDTSKGKVFVIDFKGSIDAAEVASLREEISAILAIAEKGDEVVVNVESGGGMVHGYGLASSQLDRLRQADIPLT
VCVDKVAASGGYMMACVANKIYAAPFAIVGSIGVVAQLPNFNRLLKKHEIDYEQHTAGDFKRTLTVFGENTDEGRQKFQE
ELEETHVLFKAFVSKYRPELNLEKVATGEHWYGQQAIELGLVDEILTSDDVVMSLAKDRKVYKLRYQVKKKLADKIAHGA
SLSVNAIFNRLIEKNRPM
>Mature_338_residues
MEFLYEYGMFLAKAITIVVAIVAVIIVVLASTVKHKSDKGELRITNLSEELEELKHGLKEELLSKKEFKAYEKQLKIDEK
VKDKTEGDTSKGKVFVIDFKGSIDAAEVASLREEISAILAIAEKGDEVVVNVESGGGMVHGYGLASSQLDRLRQADIPLT
VCVDKVAASGGYMMACVANKIYAAPFAIVGSIGVVAQLPNFNRLLKKHEIDYEQHTAGDFKRTLTVFGENTDEGRQKFQE
ELEETHVLFKAFVSKYRPELNLEKVATGEHWYGQQAIELGLVDEILTSDDVVMSLAKDRKVYKLRYQVKKKLADKIAHGA
SLSVNAIFNRLIEKNRPM

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=348, Percent_Identity=55.1724137931034, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1788064, Length=305, Percent_Identity=27.5409836065574, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 37628; Mature: 37628

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLYEYGMFLAKAITIVVAIVAVIIVVLASTVKHKSDKGELRITNLSEELEELKHGLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHH
ELLSKKEFKAYEKQLKIDEKVKDKTEGDTSKGKVFVIDFKGSIDAAEVASLREEISAILA
HHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
IAEKGDEVVVNVESGGGMVHGYGLASSQLDRLRQADIPLTVCVDKVAASGGYMMACVANK
HHCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHHHHH
IYAAPFAIVGSIGVVAQLPNFNRLLKKHEIDYEQHTAGDFKRTLTVFGENTDEGRQKFQE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHCCHHHHHHHHEECCCCHHHHHHHHH
ELEETHVLFKAFVSKYRPELNLEKVATGEHWYGQQAIELGLVDEILTSDDVVMSLAKDRK
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHCHHHHHHHHHHHHHCCHHHHHHHHHCCH
VYKLRYQVKKKLADKIAHGASLSVNAIFNRLIEKNRPM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFLYEYGMFLAKAITIVVAIVAVIIVVLASTVKHKSDKGELRITNLSEELEELKHGLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHH
ELLSKKEFKAYEKQLKIDEKVKDKTEGDTSKGKVFVIDFKGSIDAAEVASLREEISAILA
HHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHH
IAEKGDEVVVNVESGGGMVHGYGLASSQLDRLRQADIPLTVCVDKVAASGGYMMACVANK
HHCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHHHHH
IYAAPFAIVGSIGVVAQLPNFNRLLKKHEIDYEQHTAGDFKRTLTVFGENTDEGRQKFQE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHCCHHHHHHHHEECCCCHHHHHHHHH
ELEETHVLFKAFVSKYRPELNLEKVATGEHWYGQQAIELGLVDEILTSDDVVMSLAKDRK
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHCHHHHHHHHHHHHHCCHHHHHHHHHCCH
VYKLRYQVKKKLADKIAHGASLSVNAIFNRLIEKNRPM
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]