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The map label for this gene is sixA [H]

Identifier: 120598372

GI number: 120598372

Start: 1770902

End: 1771372

Strand: Direct

Name: sixA [H]

Synonym: Sputw3181_1554

Alternate gene names: 120598372

Gene position: 1770902-1771372 (Clockwise)

Preceding gene: 120598368

Following gene: 120598374

Centisome position: 37.61

GC content: 46.5

Gene sequence:

>471_bases
ATGCAGCTATTTTTGATGCGACATGGTGACGCAGGATTTAATGCTCAATCCGATAGGGATAGAACCCTAACCGATTTAGG
AAGGCACCATACCGTTGTGATGAGCAACTGGTTAGCTCGAAGTATCACAGATTTTGATCTTGTCTTGGTTAGCCCTTACT
TACGTGCACAGCAAACGTGGCAGGAACTGAGCCAACACTTTCCTGAGCCACGTAAGTGGCTTGTTGCCGATGATCTTGTG
CCTTCTGGCGATCCTGCTAATGTTGCCGCTTTAATTGTTGCTTATGCTGAGTTATACAAGGCAGATAGAGTGTTAGTCAT
TTCTCACATGCCATTATTGGGATACTTAGTGAGTGAATTGGTTGCAGGGGTTGAACCGCCACTGTTTGCCACCTCTGGAA
TTACCTTGGTCGATAAACATGCCGAGCAAGCGTCGATTGTGTGGCAGCACGCTCCCCATAGTATTAGCTAA

Upstream 100 bases:

>100_bases
ACTCGTATTTTGAGGTCGCTTGGGTATACAGGTTTGTCGAAACGAATTTTAGGGCTACAATTGGGATAAAACAAAAACAA
GTGTGGGTAGCGAGAGAAGT

Downstream 100 bases:

>100_bases
TTTAGATTTATATCTCTTTTACAAAACAAACGGCCCACATTAAGTGGGCCGTTTGTTTTGTAAAAGCTTGAAGCTAACTA
ACGTCTATGCGGCAGCTCAC

Product: phosphohistidine phosphatase, SixA

Products: NA

Alternate protein names: RX6 [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MQLFLMRHGDAGFNAQSDRDRTLTDLGRHHTVVMSNWLARSITDFDLVLVSPYLRAQQTWQELSQHFPEPRKWLVADDLV
PSGDPANVAALIVAYAELYKADRVLVISHMPLLGYLVSELVAGVEPPLFATSGITLVDKHAEQASIVWQHAPHSIS

Sequences:

>Translated_156_residues
MQLFLMRHGDAGFNAQSDRDRTLTDLGRHHTVVMSNWLARSITDFDLVLVSPYLRAQQTWQELSQHFPEPRKWLVADDLV
PSGDPANVAALIVAYAELYKADRVLVISHMPLLGYLVSELVAGVEPPLFATSGITLVDKHAEQASIVWQHAPHSIS
>Mature_156_residues
MQLFLMRHGDAGFNAQSDRDRTLTDLGRHHTVVMSNWLARSITDFDLVLVSPYLRAQQTWQELSQHFPEPRKWLVADDLV
PSGDPANVAALIVAYAELYKADRVLVISHMPLLGYLVSELVAGVEPPLFATSGITLVDKHAEQASIVWQHAPHSIS

Specific function: Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His- Asp phosphorelay [H]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=156, Percent_Identity=42.3076923076923, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 17408; Mature: 17408

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLFLMRHGDAGFNAQSDRDRTLTDLGRHHTVVMSNWLARSITDFDLVLVSPYLRAQQTW
CEEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHH
QELSQHFPEPRKWLVADDLVPSGDPANVAALIVAYAELYKADRVLVISHMPLLGYLVSEL
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
VAGVEPPLFATSGITLVDKHAEQASIVWQHAPHSIS
HHCCCCCCEECCCCEEEECCCHHHHEEEECCCCCCC
>Mature Secondary Structure
MQLFLMRHGDAGFNAQSDRDRTLTDLGRHHTVVMSNWLARSITDFDLVLVSPYLRAQQTW
CEEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHH
QELSQHFPEPRKWLVADDLVPSGDPANVAALIVAYAELYKADRVLVISHMPLLGYLVSEL
HHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
VAGVEPPLFATSGITLVDKHAEQASIVWQHAPHSIS
HHCCCCCCEECCCCEEEECCCHHHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9489669; 9205837; 9278503 [H]