Click here to switch to the map view.

The map label for this gene is sstT [H]

Identifier: 120598334

GI number: 120598334

Start: 1722832

End: 1724058

Strand: Direct

Name: sstT [H]

Synonym: Sputw3181_1516

Alternate gene names: 120598334

Gene position: 1722832-1724058 (Clockwise)

Preceding gene: 120598333

Following gene: 120598335

Centisome position: 36.59

GC content: 43.44

Gene sequence:

>1227_bases
ATGAAACAAGAATCATCACTTTTAGCTAAGTTGGCTAATGGCAGTCTGGTATTGCAAATTCTATTGGGGATCGCAGCAGG
GGTTATTCTTGCTAGCTTTTCACAGGATGCGGCTAAGCAAGTTGCATTTTTAGGGAGTTTATTTGTCGGGGCATTAAAAG
CAATCGCTCCTATTTTAGTGTTTATCCTCGTGGCATCGTCTATTGCCAATCAAAAGAAAAATACGCAAACCAATATGCGT
CCAATTGTGGTGCTTTATCTATTTGGGACATTTGCCGCAGCGTTAACGGCTGTCGTGTTAAGCTCGATTTTCCCCACCAA
TTTGGTATTAGTGGCAGGGATTGAAGGTACAAGCCCACCTCAAGGCATTGGTGAAGTGATTAATACGCTGCTTTTTAAAT
TAGTGGATAACCCCGTTAATGCGCTAATGACAGGCAACTATATTGGGATCCTTGCTTGGGGTGTGGGTTTAGGTTTAGCA
CTTCATCATGCCAATGATTCTACTAAGCAAGTCTTTGCCGATATGAGTCATGGTATTTCACAAATGGTACGCTTTATTAT
TCGTTTAGCGCCTATCGGTATTTTTGGTTTAGTGGCAGCAACCTTTGCCGAAACAGGCTTTGCAGCAATTGCAGGTTATG
CGCAGCTATTAGCTGTGTTGCTGAGTGCAATGGCAATTATTGCGCTGATTGTAAATCCACTTATTGTTTACGTAAAAATT
AAACGTAACCCTTATCCCTTAGTGCTTCGCTGCCTGCGTGAAAGTGGGGTAACGGCATTTTTCACCCGTTCAAGTGCGGC
GAATATTCCGGTTAACATGGCGCTGTGTGAAAAGCTTAATCTCAATAAAGATACTTATTCTGTTTCTATCCCTCTTGGTG
CGACCATCAATATGGGTGGTGCTGCAATCACTATTACAGTGCTGACCTTAGCGGCAGTTCATACGCTTGGTATTCAGGTC
GATTTACCCACAGCCTTATTATTAAGTGTTGTTGCGGCGGTTTCTGCTTGTGGTGCTTCGGGGGTTGCGGGCGGTTCTCT
ATTGCTTATTCCTCTAGCCTGTAGCTTATTTGGTATTTCCAATGATATCGCCATGCAAGTTGTGGCTGTTGGTTTTATTA
TTGGTGTGATCCAAGATGCGGCTGAAACGGCACTAAACAGTTCGACCGATGTGATTTTTACCGCAGCAGCTTGTGAAGCT
GCTGAAAACAAAGCTAAACTTGGGTAA

Upstream 100 bases:

>100_bases
AGACAAGTCCCGCCACATCCTATAAAAACCTTATTGGCCTCAAATCCGAAGGCGTGGGCTGGGTTATCTCAGCCGAAATA
TAATAATGATAGGTTAAGTC

Downstream 100 bases:

>100_bases
AGTGCTGTTATTAGCGTAAAAGAAAGCATCATATGAAGCAGTCACTTAGGTGGCTGCTTTTTTTATGGGAGTATTTATGA
TCCTTTTTGATTTTAGAACC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKQESSLLAKLANGSLVLQILLGIAAGVILASFSQDAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVVLSSIFPTNLVLVAGIEGTSPPQGIGEVINTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHANDSTKQVFADMSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAQLLAVLLSAMAIIALIVNPLIVYVKI
KRNPYPLVLRCLRESGVTAFFTRSSAANIPVNMALCEKLNLNKDTYSVSIPLGATINMGGAAITITVLTLAAVHTLGIQV
DLPTALLLSVVAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG

Sequences:

>Translated_408_residues
MKQESSLLAKLANGSLVLQILLGIAAGVILASFSQDAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVVLSSIFPTNLVLVAGIEGTSPPQGIGEVINTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHANDSTKQVFADMSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAQLLAVLLSAMAIIALIVNPLIVYVKI
KRNPYPLVLRCLRESGVTAFFTRSSAANIPVNMALCEKLNLNKDTYSVSIPLGATINMGGAAITITVLTLAAVHTLGIQV
DLPTALLLSVVAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG
>Mature_408_residues
MKQESSLLAKLANGSLVLQILLGIAAGVILASFSQDAAKQVAFLGSLFVGALKAIAPILVFILVASSIANQKKNTQTNMR
PIVVLYLFGTFAAALTAVVLSSIFPTNLVLVAGIEGTSPPQGIGEVINTLLFKLVDNPVNALMTGNYIGILAWGVGLGLA
LHHANDSTKQVFADMSHGISQMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAQLLAVLLSAMAIIALIVNPLIVYVKI
KRNPYPLVLRCLRESGVTAFFTRSSAANIPVNMALCEKLNLNKDTYSVSIPLGATINMGGAAITITVLTLAAVHTLGIQV
DLPTALLLSVVAAVSACGASGVAGGSLLLIPLACSLFGISNDIAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEA
AENKAKLG

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=269, Percent_Identity=25.6505576208178, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI223468566, Length=266, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=28.3464566929134, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI5032093, Length=301, Percent_Identity=27.906976744186, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI169790839, Length=248, Percent_Identity=22.9838709677419, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66773030, Length=246, Percent_Identity=23.1707317073171, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI21314632, Length=273, Percent_Identity=26.7399267399267, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789473, Length=403, Percent_Identity=67.2456575682382, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI1789947, Length=363, Percent_Identity=25.068870523416, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790514, Length=404, Percent_Identity=23.2673267326733, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=453, Percent_Identity=25.1655629139073, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983099, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983106, Length=250, Percent_Identity=28.4, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71996953, Length=470, Percent_Identity=23.1914893617021, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=446, Percent_Identity=22.8699551569507, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 42027; Mature: 42027

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00435 PEROXIDASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQESSLLAKLANGSLVLQILLGIAAGVILASFSQDAAKQVAFLGSLFVGALKAIAPILV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILVASSIANQKKNTQTNMRPIVVLYLFGTFAAALTAVVLSSIFPTNLVLVAGIEGTSPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGIGEVINTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHANDSTKQVFADMSHGIS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHH
QMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAQLLAVLLSAMAIIALIVNPLIVYVKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KRNPYPLVLRCLRESGVTAFFTRSSAANIPVNMALCEKLNLNKDTYSVSIPLGATINMGG
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEECCC
AAITITVLTLAAVHTLGIQVDLPTALLLSVVAAVSACGASGVAGGSLLLIPLACSLFGIS
HHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
NDIAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEAAENKAKLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQESSLLAKLANGSLVLQILLGIAAGVILASFSQDAAKQVAFLGSLFVGALKAIAPILV
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILVASSIANQKKNTQTNMRPIVVLYLFGTFAAALTAVVLSSIFPTNLVLVAGIEGTSPP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
QGIGEVINTLLFKLVDNPVNALMTGNYIGILAWGVGLGLALHHANDSTKQVFADMSHGIS
HHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHH
QMVRFIIRLAPIGIFGLVAATFAETGFAAIAGYAQLLAVLLSAMAIIALIVNPLIVYVKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KRNPYPLVLRCLRESGVTAFFTRSSAANIPVNMALCEKLNLNKDTYSVSIPLGATINMGG
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCEEECCC
AAITITVLTLAAVHTLGIQVDLPTALLLSVVAAVSACGASGVAGGSLLLIPLACSLFGIS
HHHHHHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
NDIAMQVVAVGFIIGVIQDAAETALNSSTDVIFTAAACEAAENKAKLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]