Click here to switch to the map view.

The map label for this gene is cheA [H]

Identifier: 120598270

GI number: 120598270

Start: 1633021

End: 1635240

Strand: Direct

Name: cheA [H]

Synonym: Sputw3181_1447

Alternate gene names: 120598270

Gene position: 1633021-1635240 (Clockwise)

Preceding gene: 120598269

Following gene: 120598271

Centisome position: 34.68

GC content: 45.45

Gene sequence:

>2220_bases
ATGGCCTTTGATGTAGATGAAGAGATACTCCAGGACTTTTTAATCGAAGCAGGTGAGATTTTAGAACTGCTACAGGAGCA
ACTTGTTGCCCTAGAAAATAATCCTGATGATACTGACTTGCTTAATGCCATTTTCAGGGGATTTCATACCGTTAAAGGCG
GCGCCGGCTTTCTCAGTTTGACTCCCATGGTTGATGTTTGCCATGAAGCTGAAAATACTTTTGACTTGTTACGTACCGGC
AAGCGAAAAGTTAATGCTGAATTAATGGATATCATTCTGCACGCTGTTGACGCCATTAATACTATGTTCGCTCAAACTCA
ACAGGGTGAACAACAAGACCCCGCCGATCCAGTATTATTAGCAAAATTAAAAATGCTCAGTTCTGGCGCGCCATTACCCT
CTGAATTAAACCCAAGTTCACCTGTTGCCATGACTGAACCAGAGCCAGAACCCGAGCTTGTTGAAGTTGCTGTTATTGAG
GAAATGCCCGTTGAAGCAACGGAAATAAGCGGAAGCTCAAGTATTGATGAAATTGATGAAGCGGAATTTGAGGCACTGTT
AGATGCTTTGCACGGAGAGGGGAAAGGTCCTGCTGTCAGTTCAGTAGGGAGCGCCGTGCCACCCCAATCTGTGCCAACAG
CGAAAGCTCCTGCGTCGACTGATGATATTACCGACGATGAATTTGAAGCTTTACTCGATGAGTTGCATGGTTCTGGTCAG
TTTAAAGTCGAAGTTGACGCGCCAGCTAAACCTAAAGCAGTTGTCACGCCGCCAGTGCCACCTGTTGATTCGGATGAAAT
TACCGATGATGAGTTTGAGCGATTGCTTGATGAATTGCATGGTAAAGGTGGGGCACCGGCAAAAGCAAGCATCCCTGTTG
CAGCATCATCAACACCTTCAGTTGTGCCTAAGGCTGCGCCAATAACGTCAACGGCTAACGTGGCCGCCACAGTGAATGCG
CCTGTCGTTGCGGCTAAAACTGAGATTGCTGTCGCTGATAAAGCGCCCGCGAAAGCAGCGGCATCAGCCAACGTTCCTCA
AGGTGAAACTACAGTTCGAGTCGATACTGCACGCCTTGATCAAATTATGAACATGGTCGGTGAGCTGGTATTAGTGCGAA
ATCGTCTTGTCAGTTTAGGCATTAGTCGTGATGACGAGGAAATGTCTAAAGCGCTTGCTAACTTAGATCTTGTGACTGCG
GATTTACAAGGCGCAGTGATGAAGACCCGTATGCAACCGATTAAAAAGGTGTTTGGGCGTTTTCCCCGTGTTGTTCGCGA
TTTAGCACGTACACTGAACAAAGAAATTGACTTGGTTATGATCGGTGAAGAGACCGATTTAGATAAAAACCTAGTGGAGG
CCCTCGCCGATCCTCTGGTTCACTTAGTGCGTAACTCGGTTGACCATGGCATAGAAATGCCAAATGAGCGTGAAGCTAGC
GGTAAGCCTAGAACAGGGACTATTACCTTATCTGCCAGCCAAGAAGGTGACCATATTCTGCTTAAAATCGAAGATGATGG
TGCAGGGATGGATCCTGAAAAACTTAAGCAAATCGCGATTAAACGTGGAGTGCTCGATGACGATGCCGCCGCGCGTATGA
CAGACACTGAGGCTTATAATCTGATTTTTGCGCCTGGTTTTTCAACAAAGGTGGAAATTTCCGATATTTCAGGTCGTGGC
GTTGGTATGGATGTAGTTAAGACCCGTATCGCTCAACTAAATGGTACTGTTCATATAGACTCAATGAAAGGTAAGGGGAC
GGTGCTTGAAATTAAAGTTCCCTTAACACTTGCGATTATGCCAACCCTGATGGTGGATGTGGCACAGCAAGTATTTGCTC
TGCCGCTATCGAGTGTGAATGAGATATTCCACCTTGACCTAACAAAAACCAACATTGTTGATGGACAACTCACCGTCATA
GTGCGTAATAAGGCTGTACCACTGTTCTATTTGGAACACTGGTTACATAAGAATAAAACGAGTTTTAAACATGGTGATAA
GAAACATGGCCATGTTGTTATCGTGCAATTAGGTATGATGCAGATAGGATTTGTTGTAGATGCTTTAATTGGCCAAGAAG
AAGTGGTTATCAAACCGCTTGGAGCCATGTTACACGGCACACCAGGTATGGCTGGTGCAACGATCACCTCTGATGGCGGT
ATTGCTCTGATTTTAGATGTACCAGGGCTATTAAAGCATTATGCAAAGAATAAAAGTTAG

Upstream 100 bases:

>100_bases
CCCGATAATGAATGCCGAGCTTCGTCAAGATGTGGTAACGGGTCAAGACGAAGTAGATGATCTTCTATCGAGTCTAGGTT
TCTAACTGGGAGTCAATTTG

Downstream 100 bases:

>100_bases
TTTCCAAGCTAAGGAATGGAATGGCCATTAAAGTATTAGTCGTTGATGACTCAAGTTTTTTTAGGCGACGTGTTAGTGAA
ATAGTCAATCAAGATCCTGA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRKVNAELMDIILHAVDAINTMFAQTQQGEQQDPADPVLLAKLKMLSSGAPLPSELNPSSPVAMTEPEPEPELVEVAVIE
EMPVEATEISGSSSIDEIDEAEFEALLDALHGEGKGPAVSSVGSAVPPQSVPTAKAPASTDDITDDEFEALLDELHGSGQ
FKVEVDAPAKPKAVVTPPVPPVDSDEITDDEFERLLDELHGKGGAPAKASIPVAASSTPSVVPKAAPITSTANVAATVNA
PVVAAKTEIAVADKAPAKAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTA
DLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVMIGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREAS
GKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDDDAAARMTDTEAYNLIFAPGFSTKVEISDISGRG
VGMDVVKTRIAQLNGTVHIDSMKGKGTVLEIKVPLTLAIMPTLMVDVAQQVFALPLSSVNEIFHLDLTKTNIVDGQLTVI
VRNKAVPLFYLEHWLHKNKTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGG
IALILDVPGLLKHYAKNKS

Sequences:

>Translated_739_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRKVNAELMDIILHAVDAINTMFAQTQQGEQQDPADPVLLAKLKMLSSGAPLPSELNPSSPVAMTEPEPEPELVEVAVIE
EMPVEATEISGSSSIDEIDEAEFEALLDALHGEGKGPAVSSVGSAVPPQSVPTAKAPASTDDITDDEFEALLDELHGSGQ
FKVEVDAPAKPKAVVTPPVPPVDSDEITDDEFERLLDELHGKGGAPAKASIPVAASSTPSVVPKAAPITSTANVAATVNA
PVVAAKTEIAVADKAPAKAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTA
DLQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVMIGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREAS
GKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDDDAAARMTDTEAYNLIFAPGFSTKVEISDISGRG
VGMDVVKTRIAQLNGTVHIDSMKGKGTVLEIKVPLTLAIMPTLMVDVAQQVFALPLSSVNEIFHLDLTKTNIVDGQLTVI
VRNKAVPLFYLEHWLHKNKTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGG
IALILDVPGLLKHYAKNKS
>Mature_738_residues
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTGK
RKVNAELMDIILHAVDAINTMFAQTQQGEQQDPADPVLLAKLKMLSSGAPLPSELNPSSPVAMTEPEPEPELVEVAVIEE
MPVEATEISGSSSIDEIDEAEFEALLDALHGEGKGPAVSSVGSAVPPQSVPTAKAPASTDDITDDEFEALLDELHGSGQF
KVEVDAPAKPKAVVTPPVPPVDSDEITDDEFERLLDELHGKGGAPAKASIPVAASSTPSVVPKAAPITSTANVAATVNAP
VVAAKTEIAVADKAPAKAAASANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTAD
LQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVMIGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREASG
KPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDDDAAARMTDTEAYNLIFAPGFSTKVEISDISGRGV
GMDVVKTRIAQLNGTVHIDSMKGKGTVLEIKVPLTLAIMPTLMVDVAQQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIV
RNKAVPLFYLEHWLHKNKTSFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGI
ALILDVPGLLKHYAKNKS

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=387, Percent_Identity=42.1188630490956, Blast_Score=289, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78983; Mature: 78852

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRKVNAELMDIILHAVDAINTMFAQTQQGEQQDPADPVLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLKMLSSGAPLPSELNPSSPVAMTEPEPEPELVEVAVIEEMPVEATEISGSSSIDEIDE
HHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCEECCCCCCCCHHHH
AEFEALLDALHGEGKGPAVSSVGSAVPPQSVPTAKAPASTDDITDDEFEALLDELHGSGQ
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVEVDAPAKPKAVVTPPVPPVDSDEITDDEFERLLDELHGKGGAPAKASIPVAASSTPS
EEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCC
VVPKAAPITSTANVAATVNAPVVAAKTEIAVADKAPAKAAASANVPQGETTVRVDTARLD
CCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCHHHCCCCCCCCCCEEEEEHHHHH
QIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
FPRVVRDLARTLNKEIDLVMIGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREAS
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDDDAAARMTDTEAYN
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCCCEE
LIFAPGFSTKVEISDISGRGVGMDVVKTRIAQLNGTVHIDSMKGKGTVLEIKVPLTLAIM
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCHHHHH
PTLMVDVAQQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEHWLHKNKT
HHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHHHHHHCCCC
SFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGG
CCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEECCCC
IALILDVPGLLKHYAKNKS
EEEEEECCHHHHHHHCCCC
>Mature Secondary Structure 
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRKVNAELMDIILHAVDAINTMFAQTQQGEQQDPADPVLL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
AKLKMLSSGAPLPSELNPSSPVAMTEPEPEPELVEVAVIEEMPVEATEISGSSSIDEIDE
HHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCEECCCCCCCCHHHH
AEFEALLDALHGEGKGPAVSSVGSAVPPQSVPTAKAPASTDDITDDEFEALLDELHGSGQ
HHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVEVDAPAKPKAVVTPPVPPVDSDEITDDEFERLLDELHGKGGAPAKASIPVAASSTPS
EEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCC
VVPKAAPITSTANVAATVNAPVVAAKTEIAVADKAPAKAAASANVPQGETTVRVDTARLD
CCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCHHHCCCCCCCCCCEEEEEHHHHH
QIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHH
FPRVVRDLARTLNKEIDLVMIGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREAS
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIKRGVLDDDAAARMTDTEAYN
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHCCCCCCCEE
LIFAPGFSTKVEISDISGRGVGMDVVKTRIAQLNGTVHIDSMKGKGTVLEIKVPLTLAIM
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCHHHHH
PTLMVDVAQQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEHWLHKNKT
HHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHHHHHHCCCC
SFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGG
CCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEECCCC
IALILDVPGLLKHYAKNKS
EEEEEECCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]