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The map label for this gene is flhA

Identifier: 120598264

GI number: 120598264

Start: 1626738

End: 1628837

Strand: Direct

Name: flhA

Synonym: Sputw3181_1441

Alternate gene names: 120598264

Gene position: 1626738-1628837 (Clockwise)

Preceding gene: 120598263

Following gene: 120598265

Centisome position: 34.55

GC content: 45.48

Gene sequence:

>2100_bases
ATGGATGTTAAAGCGGCTTTAGGCCAAGTTAAGCAGGTAAGACTTAGTACGTTCAAAGGCATAGGTACGCCTATGTTAGT
GCTTGCCGCATTAGCAATGATTGTATTGCCTATTCCACCGTTCTTACTCGATATTTTATTTTCCTTTAATATCGCCCTCG
CATTAATCGTATTACTAGTCGCTATTTATACTGATAGACCCTTAGATTTTGCCGCATTTCCAACCGTGCTTTTGGTTGCC
ACCTTATTGCGACTCGCCCTTAACGTGGCGTCAACCCGTGTTGTGTTGCTTGAAGGCCATAATGGGGGGGATGCCGCAGG
TAAAGTGATTGAGGCATTCGGCTCTGTGGTGATTGGTGGTAACTATGCAGTGGGTTTAGTGGTATTTATCATCCTGATCA
TTATTAACTTTGCTGTGGTGACAAAAGGTGCTGGTCGTATTGCTGAGGTGAGTGCTCGCTTTACCCTAGACGCTATGCCT
GGTAAGCAAATGGCGATTGATGCCGATCTAAACGCTGGAACTCTCAATCAAGAGCAGGCAAGGTTACGTCGAGCTGAGGT
GACCCGCGAGGCAGATTTCTATGGTGCGATGGATGGTGCCTCTAAATTCGTGAAAGGCGATGCTATTGCGGGGATTATGA
TCTTAGTCATCAACATCCTCGGTGGCTTTATTATTGGTATTGTTCAACATGGCTTGAGTTTTTCTCAAGCTGTCGAGATT
TATACGCTTTTGACCATAGGTGATGGTCTGGTTGCGCAAATTCCAGGACTATTGCTGTCCATTGCTGCGGCATTAATGGT
GACCCGTCAAAATGAATCGGGTGACATGGGCCAAATGCTGATGAGTCAGATGTTTGACAGTCATAAATCTTTAGGGATTG
CAGCGGGTGTTCTCTTTGTCATGGGCATTGTGCCAGGAATGCCTCACATGGCGTTCCTTGGCTTTGCTGTTATTACTGCT
GGTGCTGCGTATTTTGTATTTAAACGTAATGAAAATAAACGCTTAAAAGCCTTAGAACAAGTCAAAACGGGTCCGATAGA
AAGACAAGACAAAGAGCCTAAAGAGTTGAGCTGGGATGATGTACACCATGTTGACACTATCGGCCTAGAAGTGGGTTATC
GCTTAATCCCATTAGTCGATAAAGGCCAGGGTGGGGAATTATTGAGTCGTATTAAAGGGGTGCGTAAGAAACTCTCGCAG
GAGCTTGGTTTCCTCGTACCCGCAGTGCATATTCGTGACAACTTGGATTTATCCCCCAATGCCTATCGTATTTCCCTTAT
GGGGGTTGTGGTTGGTGAGGCTGATATTCGCCATGATTGTGAGTTAGCTATTAATCCTGGGCAAGTGTACGGTAAGCTTG
ATGGCATTGAAACTCGCGATCCTGCTTTTGGTCTTGAAGCGGTCTGGATTGCCCCAGAACTCCGCGAGCATGCACAGACC
TTAGGTTACACTGTGGTTGATGCTGCAACTGTCGTTGCGACCCATATTAGTCAATTACTCACCAATAATGCCGCAAAACT
TTTAGGTTACGAAGAAGTGCAACAACTGATGGATATGCTTGCTAAGCATTCTCCTAAGCTTGTTGATGGGTTTATTCCTG
ATGTGATGCCACTGGGTAGTGTCGTAAAAGTGATGCAAAACCTATTAAATGAAGGCGTTTCTGTCAGAGACTTGCGTACA
ATAGTACAAACTTTGTTAGAATACGGCACTAAGAGCAATGATACAGAAGTGTTGACCGCCGCCGTACGTATTGCGCTGAA
ACGTATGATAGTCCAAGAAATATCTGGCCCAGAACTCGAAATCCCCGTCATTACTTTGGCGCCAGAGTTGGAACAGATGT
TGCATCAATCAATGCAAGCAACTGGTGGTGATGGTCCAAATATTGAACCCGGTCTTGCGGAGCGTATGCAGCAGTCATTG
GCTGATGCGGCTCAAAAGCAAGAAATGGTTGGACAGCCTGCCATATTGTTAACGTCTGGTATGTTACGCGCGACGCTGTC
ACGGTTTGTTAAACATACTATTCCTAATCTCAGAGTGATTTCTTACCAAGAAATCCCCGATGAAAAGCAAATACGCATTG
TATCTGCTGTCGGCCAGTAG

Upstream 100 bases:

>100_bases
AATATTAATGGCTTGCTCGTTCACTCTTCAAATTTTAAGTGTCCTCTTGGCGCGATTTTTGCTTTTCCGCTTTTATACGT
CAAAGTTTAGGTAATAGTGA

Downstream 100 bases:

>100_bases
AGGACGCATAAGTGAAGATTAAACGATTTTTTGCCAAAGACATGCGTGCCGCACTGGCCCAAGTGAAAGACACTCTCGGC
TCAGATGCCGTTATCATGTC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MDVKAALGQVKQVRLSTFKGIGTPMLVLAALAMIVLPIPPFLLDILFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGTLNQEQARLRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLSFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLMSQMFDSHKSLGIAAGVLFVMGIVPGMPHMAFLGFAVITA
GAAYFVFKRNENKRLKALEQVKTGPIERQDKEPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQLLTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGSVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKHTIPNLRVISYQEIPDEKQIRIVSAVGQ

Sequences:

>Translated_699_residues
MDVKAALGQVKQVRLSTFKGIGTPMLVLAALAMIVLPIPPFLLDILFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGTLNQEQARLRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLSFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLMSQMFDSHKSLGIAAGVLFVMGIVPGMPHMAFLGFAVITA
GAAYFVFKRNENKRLKALEQVKTGPIERQDKEPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQLLTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGSVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKHTIPNLRVISYQEIPDEKQIRIVSAVGQ
>Mature_699_residues
MDVKAALGQVKQVRLSTFKGIGTPMLVLAALAMIVLPIPPFLLDILFSFNIALALIVLLVAIYTDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMP
GKQMAIDADLNAGTLNQEQARLRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLSFSQAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLMSQMFDSHKSLGIAAGVLFVMGIVPGMPHMAFLGFAVITA
GAAYFVFKRNENKRLKALEQVKTGPIERQDKEPKELSWDDVHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
LGYTVVDAATVVATHISQLLTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGSVVKVMQNLLNEGVSVRDLRT
IVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSL
ADAAQKQEMVGQPAILLTSGMLRATLSRFVKHTIPNLRVISYQEIPDEKQIRIVSAVGQ

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=687, Percent_Identity=52.4017467248908, Blast_Score=694, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75352; Mature: 75352

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVKAALGQVKQVRLSTFKGIGTPMLVLAALAMIVLPIPPFLLDILFSFNIALALIVLLV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIYTDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGTLNQEQA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHHH
RLRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLSFSQAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLMSQMFDSHKSLGIAAGVLFV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MGIVPGMPHMAFLGFAVITAGAAYFVFKRNENKRLKALEQVKTGPIERQDKEPKELSWDD
HHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
AYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
CEEEEEEEEEECCCCCCCCCEEEECCCHHHEECCCCCCCCCCCCCEEEEECHHHHHHHHH
LGYTVVDAATVVATHISQLLTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGS
HCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
VVKVMQNLLNEGVSVRDLRTIVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSLADAAQKQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MLRATLSRFVKHTIPNLRVISYQEIPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEECCCC
>Mature Secondary Structure
MDVKAALGQVKQVRLSTFKGIGTPMLVLAALAMIVLPIPPFLLDILFSFNIALALIVLLV
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AIYTDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFIILIIINFAVVTKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGTLNQEQA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHHH
RLRRAEVTREADFYGAMDGASKFVKGDAIAGIMILVINILGGFIIGIVQHGLSFSQAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGQMLMSQMFDSHKSLGIAAGVLFV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MGIVPGMPHMAFLGFAVITAGAAYFVFKRNENKRLKALEQVKTGPIERQDKEPKELSWDD
HHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCH
VHHVDTIGLEVGYRLIPLVDKGQGGELLSRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
AYRISLMGVVVGEADIRHDCELAINPGQVYGKLDGIETRDPAFGLEAVWIAPELREHAQT
CEEEEEEEEEECCCCCCCCCEEEECCCHHHEECCCCCCCCCCCCCEEEEECHHHHHHHHH
LGYTVVDAATVVATHISQLLTNNAAKLLGYEEVQQLMDMLAKHSPKLVDGFIPDVMPLGS
HCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHH
VVKVMQNLLNEGVSVRDLRTIVQTLLEYGTKSNDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPGLAERMQQSLADAAQKQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MLRATLSRFVKHTIPNLRVISYQEIPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]