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The map label for this gene is ltaE [H]

Identifier: 120598161

GI number: 120598161

Start: 1517567

End: 1518580

Strand: Direct

Name: ltaE [H]

Synonym: Sputw3181_1338

Alternate gene names: 120598161

Gene position: 1517567-1518580 (Clockwise)

Preceding gene: 120598157

Following gene: 120598165

Centisome position: 32.23

GC content: 44.48

Gene sequence:

>1014_bases
ATGATAGATTTACGCAGTGATACTGTTACCCAGCCGACTGAAGCCATGCGGTTAGCTATGTCCAGAGCTGAAGTCGGAGA
CGATGTATATGGTGATGATCCTACCGTAAACAGCTTACAGGATATGGCTGCTGAGATGTTTGGTTTTGAGAGTGCGCTGT
TTACGGTTTCTGGCACTCAAGCAAATTTACTTGCTTTAATGGCTCATTGTGAGCGTGGGGATGAGTATTTGTGCGGCCAA
CAGGCGCATAATTATAAATTTGAGGGCGGCGGTGCTGCAGTTTTAGGCAGTATTCAGCCGCAGCCATTGATAAATCAATT
GGACGGCACTATTGCGCTTGCAGACATAGAGGCTGCGATTAAACCTGATGATATCCACTTTGCTCGCACCCGTTTATTGA
GTTTAGAAAACACCATCGCGGGTAAAATATTACCGCAGACCTATCTGGCAAATGCACAGGCTTTAGCTTTTCATCGTGGT
TTGAAAATTCACCTTGATGGGGCGAGAGTAGCCAATGCTGCGGTAGCACAAAATATCCCTATTAGTGATATCACTGCGCA
TTTTGATTCTGTTTCCATCTGCCTTTCAAAGGGGCTTTGCGCGCCCGTGGGTTCATTACTCTTAGGTGATGAGCGTTTGA
TTAAAAAGGCAATACGTTGGCGTAAAATGCTTGGCGGTGGTATGCGTCAAGCGGGGATATTAGCTGCTGCAGGTAAACTG
GCATTGACAGAACAAGTAGAGAGACTTGCTGAAGATCATGAAAGTGCAACTTATTTTGCCCAGAAATTAACCGAGTTTGC
CGAATTTGAGGTTGATTTAACCACGGTACAAACCAATATGGTGTTTGCGACTTTGGCGCCGCATATTGACGCTATGTTAT
TAGCCAAACGGTGCCAAGAGGCTGGGATTTTAATTAGCCCTGGACGGACAATTCGTTTCGTTACACATAAGGATGTTACT
CGTCAGGATATTGATAAAGTGCTAAATATCTTTAAGTTACATTTTCAAGCGTAA

Upstream 100 bases:

>100_bases
ATGGTTATGTTGCTCTTGGCTTAGGCAAACTATACAAATTTTATCTTTGGCGTTAGAGTCACTAACTCATTGTGATTACG
CAAATAAAATTGAGGGCAAG

Downstream 100 bases:

>100_bases
TTGAACCTTCGCTATTTACTGTCCGAAAGGTTCGTCTGGCAAGTTCTTGTGCTTACCTTCGCCATGCGAACCACTCGTTA
TTTGAGTTGAATAACGATAG

Product: threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTVSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLINQLDGTIALADIEAAIKPDDIHFARTRLLSLENTIAGKILPQTYLANAQALAFHRG
LKIHLDGARVANAAVAQNIPISDITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVERLAEDHESATYFAQKLTEFAEFEVDLTTVQTNMVFATLAPHIDAMLLAKRCQEAGILISPGRTIRFVTHKDVT
RQDIDKVLNIFKLHFQA

Sequences:

>Translated_337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTVSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLINQLDGTIALADIEAAIKPDDIHFARTRLLSLENTIAGKILPQTYLANAQALAFHRG
LKIHLDGARVANAAVAQNIPISDITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVERLAEDHESATYFAQKLTEFAEFEVDLTTVQTNMVFATLAPHIDAMLLAKRCQEAGILISPGRTIRFVTHKDVT
RQDIDKVLNIFKLHFQA
>Mature_337_residues
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTVSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLINQLDGTIALADIEAAIKPDDIHFARTRLLSLENTIAGKILPQTYLANAQALAFHRG
LKIHLDGARVANAAVAQNIPISDITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVERLAEDHESATYFAQKLTEFAEFEVDLTTVQTNMVFATLAPHIDAMLLAKRCQEAGILISPGRTIRFVTHKDVT
RQDIDKVLNIFKLHFQA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=327, Percent_Identity=56.2691131498471, Blast_Score=363, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI193206522, Length=341, Percent_Identity=41.9354838709677, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI193206520, Length=341, Percent_Identity=41.9354838709677, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI193206524, Length=341, Percent_Identity=41.9354838709677, Blast_Score=239, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320789, Length=331, Percent_Identity=38.368580060423, Blast_Score=199, Evalue=6e-52,
Organism=Drosophila melanogaster, GI21355439, Length=311, Percent_Identity=45.3376205787781, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36616; Mature: 36616

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTVSGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLINQLDGTIALADIEAAI
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCCCHHHHHCCCCEEEEEEHHHC
KPDDIHFARTRLLSLENTIAGKILPQTYLANAQALAFHRGLKIHLDGARVANAAVAQNIP
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCEEEECCCHHHHHHHHCCCC
ISDITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHH
ALTEQVERLAEDHESATYFAQKLTEFAEFEVDLTTVQTNMVFATLAPHIDAMLLAKRCQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHEEEHHHHHHHHHHHHHHHHH
AGILISPGRTIRFVTHKDVTRQDIDKVLNIFKLHFQA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDLRSDTVTQPTEAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTVSGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLINQLDGTIALADIEAAI
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCCCHHHHHCCCCEEEEEEHHHC
KPDDIHFARTRLLSLENTIAGKILPQTYLANAQALAFHRGLKIHLDGARVANAAVAQNIP
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCEEEECCCHHHHHHHHCCCC
ISDITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHH
ALTEQVERLAEDHESATYFAQKLTEFAEFEVDLTTVQTNMVFATLAPHIDAMLLAKRCQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHEEEHHHHHHHHHHHHHHHHH
AGILISPGRTIRFVTHKDVTRQDIDKVLNIFKLHFQA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]