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The map label for this gene is mlrA [H]

Identifier: 120598120

GI number: 120598120

Start: 1481333

End: 1482313

Strand: Direct

Name: mlrA [H]

Synonym: Sputw3181_1297

Alternate gene names: 120598120

Gene position: 1481333-1482313 (Clockwise)

Preceding gene: 120598119

Following gene: 120598121

Centisome position: 31.46

GC content: 44.14

Gene sequence:

>981_bases
ATGAAAGAAGATCAACCGTCCATGCCTGATGCAGAATATCGAGATGAAGTCTTACTCCCAATCGGGGAAGTATCTTCAAT
TACAGGGGTTAATGCGGTGACATTAAGGGCATGGCAGCGCCGTTTTGGTTTAGTGATCCCAGAACGAACTCCCAAGGGAC
ACAGGTTATACACGGCAGAAAATATTAAAGAAATTCATGAGATCAATGCTTGGTTGGCTAAAGGGGTCGCGATTAGTAAA
GTGAAACCTTTGCTGTTGAGTGCCGCGAAATCTTTGCCCTTAGAAGCCACTCAAACAGAAGTGACTGATATTTGGACTGA
ACAAATTGCAGCCTTGACGGCTGCACTGTTGGCATTTAATCAACATAAGTTACACCAGATATTGGATGAAGCAATCGGCT
TATACCCGTTTCATTTAGTCAAAGATAAGTTATTGAATCCTTGGCTGAGTCATATTGATAGTTTACTAGTCGAACGGCTC
GATGCTGAGTTAGTGACCGCATGGCTAAAGAGTGAATTACTTAGTCGGACAGGCGGACGTTTTGTGCTTGCAGGGCAAGC
ACATACGGCAAGAGTTGTTGTAATAACACTCTGCCGTAATACACAGTTATCAGCAAATGCAATACGGACTAATACCCTAT
TTTCACTCATTTTGTTACTTGAATTAGCGGCGTTACGAGTGTCGGTTATTGATCTTGGTGAGCAGGTTATTGGGAATTTA
GCGCTCTTAAATGGCAGGCTCAAAGTCGATGCACTTTTGGTTATTCCTGATGCTAGTCATTCCGGTTCTGAGCAGGCTGA
AATACTCGATACCCTAAAACAAATGGCTTTCCCATGCTGTGTCATTGGACCCTTTGCCCCCATGTATACCTCGTTATCCA
CATTTGCTATGCCAACGGTAGCGGCGTTGATTGATTCTGTGTCACCTAAATCGCAGGCTTCGACTCGGCATCAAACGGTC
AATCTGCAGCAGGGTGTATAA

Upstream 100 bases:

>100_bases
AGACCAAGTGTATTTGAATCCTCATCCTGAGGCGTTAAAACTGCGTTACGCATATTAATTTATGGTCGCAAGCAATTGTT
TAACCAAATAAGTGATTAAG

Downstream 100 bases:

>100_bases
GTAAAAGGCGGTATTAAAAATATGAGTGGAGATAACAGTGATATCACTTAAAGAACAAATGGCTACGTCAAATGTAGGCG
ATACACTGATGTGGTTTCGT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKEDQPSMPDAEYRDEVLLPIGEVSSITGVNAVTLRAWQRRFGLVIPERTPKGHRLYTAENIKEIHEINAWLAKGVAISK
VKPLLLSAAKSLPLEATQTEVTDIWTEQIAALTAALLAFNQHKLHQILDEAIGLYPFHLVKDKLLNPWLSHIDSLLVERL
DAELVTAWLKSELLSRTGGRFVLAGQAHTARVVVITLCRNTQLSANAIRTNTLFSLILLLELAALRVSVIDLGEQVIGNL
ALLNGRLKVDALLVIPDASHSGSEQAEILDTLKQMAFPCCVIGPFAPMYTSLSTFAMPTVAALIDSVSPKSQASTRHQTV
NLQQGV

Sequences:

>Translated_326_residues
MKEDQPSMPDAEYRDEVLLPIGEVSSITGVNAVTLRAWQRRFGLVIPERTPKGHRLYTAENIKEIHEINAWLAKGVAISK
VKPLLLSAAKSLPLEATQTEVTDIWTEQIAALTAALLAFNQHKLHQILDEAIGLYPFHLVKDKLLNPWLSHIDSLLVERL
DAELVTAWLKSELLSRTGGRFVLAGQAHTARVVVITLCRNTQLSANAIRTNTLFSLILLLELAALRVSVIDLGEQVIGNL
ALLNGRLKVDALLVIPDASHSGSEQAEILDTLKQMAFPCCVIGPFAPMYTSLSTFAMPTVAALIDSVSPKSQASTRHQTV
NLQQGV
>Mature_326_residues
MKEDQPSMPDAEYRDEVLLPIGEVSSITGVNAVTLRAWQRRFGLVIPERTPKGHRLYTAENIKEIHEINAWLAKGVAISK
VKPLLLSAAKSLPLEATQTEVTDIWTEQIAALTAALLAFNQHKLHQILDEAIGLYPFHLVKDKLLNPWLSHIDSLLVERL
DAELVTAWLKSELLSRTGGRFVLAGQAHTARVVVITLCRNTQLSANAIRTNTLFSLILLLELAALRVSVIDLGEQVIGNL
ALLNGRLKVDALLVIPDASHSGSEQAEILDTLKQMAFPCCVIGPFAPMYTSLSTFAMPTVAALIDSVSPKSQASTRHQTV
NLQQGV

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=130, Percent_Identity=38.4615384615385, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787409, Length=126, Percent_Identity=38.0952380952381, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 35696; Mature: 35696

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDQPSMPDAEYRDEVLLPIGEVSSITGVNAVTLRAWQRRFGLVIPERTPKGHRLYTAE
CCCCCCCCCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCEEEEHH
NIKEIHEINAWLAKGVAISKVKPLLLSAAKSLPLEATQTEVTDIWTEQIAALTAALLAFN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QHKLHQILDEAIGLYPFHLVKDKLLNPWLSHIDSLLVERLDAELVTAWLKSELLSRTGGR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FVLAGQAHTARVVVITLCRNTQLSANAIRTNTLFSLILLLELAALRVSVIDLGEQVIGNL
EEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLNGRLKVDALLVIPDASHSGSEQAEILDTLKQMAFPCCVIGPFAPMYTSLSTFAMPTV
HHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHH
AALIDSVSPKSQASTRHQTVNLQQGV
HHHHHCCCCCHHHHHHHHEEECCCCC
>Mature Secondary Structure
MKEDQPSMPDAEYRDEVLLPIGEVSSITGVNAVTLRAWQRRFGLVIPERTPKGHRLYTAE
CCCCCCCCCCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCEEEEHH
NIKEIHEINAWLAKGVAISKVKPLLLSAAKSLPLEATQTEVTDIWTEQIAALTAALLAFN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QHKLHQILDEAIGLYPFHLVKDKLLNPWLSHIDSLLVERLDAELVTAWLKSELLSRTGGR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FVLAGQAHTARVVVITLCRNTQLSANAIRTNTLFSLILLLELAALRVSVIDLGEQVIGNL
EEEECCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLNGRLKVDALLVIPDASHSGSEQAEILDTLKQMAFPCCVIGPFAPMYTSLSTFAMPTV
HHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHH
AALIDSVSPKSQASTRHQTVNLQQGV
HHHHHCCCCCHHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 11677609 [H]