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The map label for this gene is czrA [H]

Identifier: 120597950

GI number: 120597950

Start: 1270783

End: 1271136

Strand: Direct

Name: czrA [H]

Synonym: Sputw3181_1122

Alternate gene names: 120597950

Gene position: 1270783-1271136 (Clockwise)

Preceding gene: 120597949

Following gene: 120597951

Centisome position: 26.99

GC content: 56.78

Gene sequence:

>354_bases
ATGACTTTACGCAAACAAGTTAACGCGCCCCGCGGTGCAAGCGACGATCTGGCTTCTTTGTCACAGAATGACGTTACGAT
CCTGGCCGAGACCTTCCGCCTACTGGGCGACCCGTCTCGGTTGAGAATAATGCTGTGCTGCATGAAGGGTTCCTCCTCGG
TTGGGGACATCGCGGAATCCCTCGAGCTTTCGCAGTCGCTGGTCAGTCACCACCTGCGGCTGCTGCGTGGAGCCCGCCTT
GTGAAGGGGGTGCGCCAGGCCAAGCAAATTTTCTATGAGGTGGACGACAAGCATGTGAACCAAGTGCTGCTGGACATGTC
CACTCACATCGTCGAAGAGCACAACGACGATTAG

Upstream 100 bases:

>100_bases
GCTGTCTCCTGATCTTTGTCGGCGAGTGCGATCAAATTATCGCAGCCTCGTTAATTCTGAACGGCATGAGTAGCTGTTCG
AGAGTTGGAATTTTTGAGAA

Downstream 100 bases:

>100_bases
CCGCGGGCGAAGCGCTCGTTGCGATGCGGATTGCGATCTATTACAAGCTGGGGCCGTATGACCGCCCGCGGCTACACTCA
ATGAGATGAATGCGGGTCCA

Product: regulatory protein, ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MTLRKQVNAPRGASDDLASLSQNDVTILAETFRLLGDPSRLRIMLCCMKGSSSVGDIAESLELSQSLVSHHLRLLRGARL
VKGVRQAKQIFYEVDDKHVNQVLLDMSTHIVEEHNDD

Sequences:

>Translated_117_residues
MTLRKQVNAPRGASDDLASLSQNDVTILAETFRLLGDPSRLRIMLCCMKGSSSVGDIAESLELSQSLVSHHLRLLRGARL
VKGVRQAKQIFYEVDDKHVNQVLLDMSTHIVEEHNDD
>Mature_116_residues
TLRKQVNAPRGASDDLASLSQNDVTILAETFRLLGDPSRLRIMLCCMKGSSSVGDIAESLELSQSLVSHHLRLLRGARLV
KGVRQAKQIFYEVDDKHVNQVLLDMSTHIVEEHNDD

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13054; Mature: 12923

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRKQVNAPRGASDDLASLSQNDVTILAETFRLLGDPSRLRIMLCCMKGSSSVGDIAES
CCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHEEECCCCCCHHHHHHH
LELSQSLVSHHLRLLRGARLVKGVRQAKQIFYEVDDKHVNQVLLDMSTHIVEEHNDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLRKQVNAPRGASDDLASLSQNDVTILAETFRLLGDPSRLRIMLCCMKGSSSVGDIAES
CCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHEEECCCCCCHHHHHHH
LELSQSLVSHHLRLLRGARLVKGVRQAKQIFYEVDDKHVNQVLLDMSTHIVEEHNDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]