Click here to switch to the map view.

The map label for this gene is hmrR2 [H]

Identifier: 120597949

GI number: 120597949

Start: 1269595

End: 1270020

Strand: Direct

Name: hmrR2 [H]

Synonym: Sputw3181_1120

Alternate gene names: 120597949

Gene position: 1269595-1270020 (Clockwise)

Preceding gene: 120597946

Following gene: 120597950

Centisome position: 26.96

GC content: 42.96

Gene sequence:

>426_bases
ATGAACATTGGTGATGCAGCCCGCTTATCGGGAGTTTCGGCGAAAATGATTCGTTACTATGAGGAGGTTGGGCTAATACC
ATCAGTCTCCAGAACAGAGGCTGGTTATCGGATCTACAAAGATGCCGATGTTTATAAGTTACATTTTATACGTCGATGTC
GAGATCTCGGTTTTTCTCTGTCACAGGCAGGAGAGTTACTTTCTCTTTGGGGAAATCATTCGCGTCAGAGTGCAGATGTT
AAAAGTATAGTTGAATCTCATATTAATGATTTAACCTTAAAAATTGAAGAATTTCAACGTATGGCATCAATTCTTACCAC
ACTCTCTGCTTGCTGCGCGGGAAATGAAAAACCCGACTGCCCAATACTGAAGGCTCTCTACCTCGCGGATACTTCCCATC
TGCAGGACATAGAAAGCTGCCCTTAA

Upstream 100 bases:

>100_bases
TGGTTCAATGGATTAGGAAATTTCCTTCAATAAATGTTACCCGAAACTATGTTACTTAAAGCTAACTACAGTATTAGTAA
AAATCATTTGGGAGGTGAAG

Downstream 100 bases:

>100_bases
ACTTTCGACTCCCTTCAATGTTATTAGGTGATCGCCATGGGTGGGAATACGCAGTTTAGCTCGAAAGCTAGACCTTTGTC
GTCAGGATGAGGTCGCATGC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MNIGDAARLSGVSAKMIRYYEEVGLIPSVSRTEAGYRIYKDADVYKLHFIRRCRDLGFSLSQAGELLSLWGNHSRQSADV
KSIVESHINDLTLKIEEFQRMASILTTLSACCAGNEKPDCPILKALYLADTSHLQDIESCP

Sequences:

>Translated_141_residues
MNIGDAARLSGVSAKMIRYYEEVGLIPSVSRTEAGYRIYKDADVYKLHFIRRCRDLGFSLSQAGELLSLWGNHSRQSADV
KSIVESHINDLTLKIEEFQRMASILTTLSACCAGNEKPDCPILKALYLADTSHLQDIESCP
>Mature_141_residues
MNIGDAARLSGVSAKMIRYYEEVGLIPSVSRTEAGYRIYKDADVYKLHFIRRCRDLGFSLSQAGELLSLWGNHSRQSADV
KSIVESHINDLTLKIEEFQRMASILTTLSACCAGNEKPDCPILKALYLADTSHLQDIESCP

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=39.6825396825397, Blast_Score=109, Evalue=8e-26,
Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=36.9230769230769, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15712; Mature: 15712

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGDAARLSGVSAKMIRYYEEVGLIPSVSRTEAGYRIYKDADVYKLHFIRRCRDLGFSL
CCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCH
SQAGELLSLWGNHSRQSADVKSIVESHINDLTLKIEEFQRMASILTTLSACCAGNEKPDC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILKALYLADTSHLQDIESCP
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIGDAARLSGVSAKMIRYYEEVGLIPSVSRTEAGYRIYKDADVYKLHFIRRCRDLGFSL
CCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCH
SQAGELLSLWGNHSRQSADVKSIVESHINDLTLKIEEFQRMASILTTLSACCAGNEKPDC
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILKALYLADTSHLQDIESCP
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]