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The map label for this gene is polC [H]

Identifier: 120597914

GI number: 120597914

Start: 1232005

End: 1232910

Strand: Direct

Name: polC [H]

Synonym: Sputw3181_1084

Alternate gene names: 120597914

Gene position: 1232005-1232910 (Clockwise)

Preceding gene: 120597911

Following gene: 120597915

Centisome position: 26.17

GC content: 49.56

Gene sequence:

>906_bases
ATGACAAGAGCCCCTGCGCCATTTCCGCTAGAGCGCCTCGCGGATATCCCAGAAAGACCAGAAGATTTTAGATTGCTGGA
GCGTATTCCATTAACGCGTGAGCCGCAGACTTGGCCACTTGAACTTTCTCCTGTGGTCGGTGATGAACGGCCAATGGTGC
TGCTCGATACAGAGACAACCGGACTGTCTGCCGATGACGAGTCCATTATTGAGCTTGGTATGGTTAAGGTGCTTTACAGC
CCCTCTGCTAAGCGGATTGTGTCGATTGTTGATGTGATCAGCCTGTATGAAGATCCCGGCAAGCCAATCCCCGAGCTGAT
TACCGAGTTAACCGGTATTACCGATGATATGGTTCAAGGCCAGCACATTGATGATTCACTGGTAGCGAGTTGGTTATCCG
ATGATCCGCTGGTGGTTGCACACAATGCGCAGTTTGATCGTCCTTTCTTTGAAAAGCGGTTTGCTGCATTAGGACATCTA
TCTTGGGCCTGTTCAGCCAGTGGCATAGATTGGAAGGCGCTGGGTTTTGAAAGTCGAAAGCTTGAGTACCTGCTGCTTCG
CTTAGGTTGGTTTTATGAAGGACACCGAGCTGCAACTGATTGTTTCGCGATGGCCTGGTTGTTCCATTTGTTGCCCGAGT
CCGTTGCAAACTTGTTGTCTGAAGCAGACAGGCGAACTGTGTTAGTTCGTGCGTTTGGTGCGCCGTTTGACGTAAAGGAC
TATTTGAAAGAGCGTGGTTACCGCTGGCATGACGGTGTTAAAGGTGCCAACAAACATTGGTGGCGCGAAATCAGCGAAGA
CGAGTTGCCGCAGGAACAAACTTACCTGGATGATTTGTATCATCGTGGCTCAGAACATGCCCACTATGACTACAAAGATG
CCCGTAATCGATTTAAAGCTTTGTAG

Upstream 100 bases:

>100_bases
AAGATTAAAAAAACGCTGAGGTATCCAAGGTGCATTTTGTACAACCTGTGGCACAGTTAAATAACCCAAAGCGAACAATA
GAATTGAAGAGGAACCATCA

Downstream 100 bases:

>100_bases
CTCTCTACAAGGTAAGCCTTGCATATTTGAAAACCTCTGGAAAATGGAAAGTGAACTCATGGTTTAACCAACAAGAGGAA
TCTTTCCATGTACCAAGACA

Product: exonuclease, RNase T and DNA polymerase III

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTRAPAPFPLERLADIPERPEDFRLLERIPLTREPQTWPLELSPVVGDERPMVLLDTETTGLSADDESIIELGMVKVLYS
PSAKRIVSIVDVISLYEDPGKPIPELITELTGITDDMVQGQHIDDSLVASWLSDDPLVVAHNAQFDRPFFEKRFAALGHL
SWACSASGIDWKALGFESRKLEYLLLRLGWFYEGHRAATDCFAMAWLFHLLPESVANLLSEADRRTVLVRAFGAPFDVKD
YLKERGYRWHDGVKGANKHWWREISEDELPQEQTYLDDLYHRGSEHAHYDYKDARNRFKAL

Sequences:

>Translated_301_residues
MTRAPAPFPLERLADIPERPEDFRLLERIPLTREPQTWPLELSPVVGDERPMVLLDTETTGLSADDESIIELGMVKVLYS
PSAKRIVSIVDVISLYEDPGKPIPELITELTGITDDMVQGQHIDDSLVASWLSDDPLVVAHNAQFDRPFFEKRFAALGHL
SWACSASGIDWKALGFESRKLEYLLLRLGWFYEGHRAATDCFAMAWLFHLLPESVANLLSEADRRTVLVRAFGAPFDVKD
YLKERGYRWHDGVKGANKHWWREISEDELPQEQTYLDDLYHRGSEHAHYDYKDARNRFKAL
>Mature_300_residues
TRAPAPFPLERLADIPERPEDFRLLERIPLTREPQTWPLELSPVVGDERPMVLLDTETTGLSADDESIIELGMVKVLYSP
SAKRIVSIVDVISLYEDPGKPIPELITELTGITDDMVQGQHIDDSLVASWLSDDPLVVAHNAQFDRPFFEKRFAALGHLS
WACSASGIDWKALGFESRKLEYLLLRLGWFYEGHRAATDCFAMAWLFHLLPESVANLLSEADRRTVLVRAFGAPFDVKDY
LKERGYRWHDGVKGANKHWWREISEDELPQEQTYLDDLYHRGSEHAHYDYKDARNRFKAL

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 34551; Mature: 34420

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAPAPFPLERLADIPERPEDFRLLERIPLTREPQTWPLELSPVVGDERPMVLLDTETT
CCCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEECCCC
GLSADDESIIELGMVKVLYSPSAKRIVSIVDVISLYEDPGKPIPELITELTGITDDMVQG
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCC
QHIDDSLVASWLSDDPLVVAHNAQFDRPFFEKRFAALGHLSWACSASGIDWKALGFESRK
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LEYLLLRLGWFYEGHRAATDCFAMAWLFHLLPESVANLLSEADRRTVLVRAFGAPFDVKD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHH
YLKERGYRWHDGVKGANKHWWREISEDELPQEQTYLDDLYHRGSEHAHYDYKDARNRFKA
HHHHCCCCCCCCCCCCCHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
L
C
>Mature Secondary Structure 
TRAPAPFPLERLADIPERPEDFRLLERIPLTREPQTWPLELSPVVGDERPMVLLDTETT
CCCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCEEEEECCCC
GLSADDESIIELGMVKVLYSPSAKRIVSIVDVISLYEDPGKPIPELITELTGITDDMVQG
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCC
QHIDDSLVASWLSDDPLVVAHNAQFDRPFFEKRFAALGHLSWACSASGIDWKALGFESRK
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LEYLLLRLGWFYEGHRAATDCFAMAWLFHLLPESVANLLSEADRRTVLVRAFGAPFDVKD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHH
YLKERGYRWHDGVKGANKHWWREISEDELPQEQTYLDDLYHRGSEHAHYDYKDARNRFKA
HHHHCCCCCCCCCCCCCHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901559; 2499883; 1840638; 9384377; 7679775; 2515995; 8491709; 1312503 [H]