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The map label for this gene is hflK [H]

Identifier: 120597494

GI number: 120597494

Start: 730799

End: 731941

Strand: Direct

Name: hflK [H]

Synonym: Sputw3181_0663

Alternate gene names: 120597494

Gene position: 730799-731941 (Clockwise)

Preceding gene: 120597493

Following gene: 120597495

Centisome position: 15.52

GC content: 45.23

Gene sequence:

>1143_bases
ATGGCTTGGAATGAGCCCGGTAACAAGGGTAATGATCCTTGGGGAAATAAAGGTGGTAACGACAAAGGACCACCGGACCT
TGATGAGGTTTTTCGTAATCTTTCAAAGCGCTTTGGCGGCAAAGGGACTGGTTCAGGCCAATCTTTTAGTTCGCTAAGCT
TAATCATCATACTTGCCATTGCTTTAGCTGTTTGGGGACTCTCGGGTTTTTATACAATTAAAGAGGCCGAGCGTGGTGTG
GCATTGCGCTTTGGTAAACACATTGGTGAGATTGGGCCAGGACTTCACTGGAAAGCGACTTTTATTGATGAAATTTATCC
CGTCGACATTCAATCGGTTCGCTCTATTCCTGCGTCTGGTAGTATGCTGACGTCCGATGAAAACGTCGTGAAGGTAGAAC
TCGATGTACAGTATCGAATTTTAGATGCTTATTCATACCTGTTCAGTGCTGTCGATGCGAACGCCAGCTTACGTGAAGCA
ACAGATAGCGCCCTGCGTTATGTGATTGGTCACAATAAGATGGATGATATTTTAACGACGGGTCGTGATGCTATTCGCCG
CGATACGTGGAAAGAATTAGAACGTATCCTTGAACCATACAAATTGGGTCTCTCGGTTGTGGATGTTAACTTCTTACCGG
CACGTCCACCTGAAGAAGTGAAAGATGCTTTCGATGATGCGATTTCTGCCCAGGAAGATGAACAGCGTTTTATTCGTGAA
GCTGAAGCTTATGCCCGTGAGATTGAACCTAAAGCGCGTGGTGAAGTTGAGCGCATGGCACAACAAGCTAATGCTTATAA
AGAACGTGAAATCTTAGAGGCTCGCGGTAAAGTGGCTCGTTTCGAGTTGTTGTTACCTGAGTATCAAGCATCGCCAGAGG
TAACCCGTAAGCGTTTGTATCTTGATACAATGCAACAAGTGATGACAGAGACAAACAAAGTACTTATTGATGCTAAGAAC
AATGGTAACTTGATGTACTTGCCGTTAGATAAGTTAATGAAAGAGAAGCCTGCGACACCTGAACTTGAGCCTAAACCTCA
GCAGAATGTCAATTCTTCATCTGTATCAACGACTCGCATTAGTAGTGAGCCTTTGAGTGGACGTCCGTCCCGCGATGATC
GTACTCGCCAAGGGAGGGATTAA

Upstream 100 bases:

>100_bases
ACAGAGTCAGGGTGAGTTAGAAACCTTTATCTTCGATGCGTCGATAGAAAAGGCTGTTTGTTAATAATCTAATTTATTTC
ATCCACTTATGGAGTGCTAA

Downstream 100 bases:

>100_bases
TTCATGGGTAGATTAGGTATTATTCTTATCGCCATCGTTTTAGGTGTTGTCCTATCTTCTGTGATGGTTGTGAGTGAAGG
TGAGCGAGCTATCGTCGCAC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGTGSGQSFSSLSLIIILAIALAVWGLSGFYTIKEAERGV
ALRFGKHIGEIGPGLHWKATFIDEIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREA
TDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLSVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
AEAYAREIEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQASPEVTRKRLYLDTMQQVMTETNKVLIDAKN
NGNLMYLPLDKLMKEKPATPELEPKPQQNVNSSSVSTTRISSEPLSGRPSRDDRTRQGRD

Sequences:

>Translated_380_residues
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGTGSGQSFSSLSLIIILAIALAVWGLSGFYTIKEAERGV
ALRFGKHIGEIGPGLHWKATFIDEIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREA
TDSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLSVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
AEAYAREIEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQASPEVTRKRLYLDTMQQVMTETNKVLIDAKN
NGNLMYLPLDKLMKEKPATPELEPKPQQNVNSSSVSTTRISSEPLSGRPSRDDRTRQGRD
>Mature_379_residues
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGTGSGQSFSSLSLIIILAIALAVWGLSGFYTIKEAERGVA
LRFGKHIGEIGPGLHWKATFIDEIYPVDIQSVRSIPASGSMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREAT
DSALRYVIGHNKMDDILTTGRDAIRRDTWKELERILEPYKLGLSVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIREA
EAYAREIEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQASPEVTRKRLYLDTMQQVMTETNKVLIDAKNN
GNLMYLPLDKLMKEKPATPELEPKPQQNVNSSSVSTTRISSEPLSGRPSRDDRTRQGRD

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=361, Percent_Identity=53.7396121883656, Blast_Score=360, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 42594; Mature: 42462

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGTGSGQSFSSLSLIIILAI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALAVWGLSGFYTIKEAERGVALRFGKHIGEIGPGLHWKATFIDEIYPVDIQSVRSIPASG
HHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCHHHHHCCCCCC
SMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILTT
CEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
GRDAIRRDTWKELERILEPYKLGLSVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
AEAYAREIEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQASPEVTRKRLY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHH
LDTMQQVMTETNKVLIDAKNNGNLMYLPLDKLMKEKPATPELEPKPQQNVNSSSVSTTRI
HHHHHHHHHCCCEEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEE
SSEPLSGRPSRDDRTRQGRD
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWNEPGNKGNDPWGNKGGNDKGPPDLDEVFRNLSKRFGGKGTGSGQSFSSLSLIIILAI
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALAVWGLSGFYTIKEAERGVALRFGKHIGEIGPGLHWKATFIDEIYPVDIQSVRSIPASG
HHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCHHHHHCCCCCC
SMLTSDENVVKVELDVQYRILDAYSYLFSAVDANASLREATDSALRYVIGHNKMDDILTT
CEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
GRDAIRRDTWKELERILEPYKLGLSVVDVNFLPARPPEEVKDAFDDAISAQEDEQRFIRE
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
AEAYAREIEPKARGEVERMAQQANAYKEREILEARGKVARFELLLPEYQASPEVTRKRLY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHH
LDTMQQVMTETNKVLIDAKNNGNLMYLPLDKLMKEKPATPELEPKPQQNVNSSSVSTTRI
HHHHHHHHHCCCEEEEEECCCCCEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEE
SSEPLSGRPSRDDRTRQGRD
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]