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The map label for this gene is dtd [H]

Identifier: 120597104

GI number: 120597104

Start: 299883

End: 300320

Strand: Direct

Name: dtd [H]

Synonym: Sputw3181_0273

Alternate gene names: 120597104

Gene position: 299883-300320 (Clockwise)

Preceding gene: 120597103

Following gene: 120597105

Centisome position: 6.37

GC content: 45.66

Gene sequence:

>438_bases
GTGATAGCGTTAATTCAAAGAGTGAGCCGTGCCAGCGTGGTGGTCGATAACCAAACCCTAGGTTCAATTGATAAAGGCTT
GTTAGTCTTGCTTGGGGTTGAGCGGGAAGATAACCGCGAAAAAATGGAAAAATTAGCCACTAAGGTGATGAGTTATCGCG
TGTTTTCCGATGAAAATGGCAAGATGAATCTCAATTTAGAACAAGTCGGTGGATCTTTATTAGTCGTGTCACAATTTACC
TTGGCCGCCGATACAGGCAGAGGTTTGAGGCCGAGTTTTTCTGGGGCAGGTACGCCAGATCAGGCATTGACATTGTATGA
AGAGTTTGTTGCTTTTTGCCGCGATAAGGGTGTTACTACAGAAACCGGACAGTTCGGTGCCGATATGCAAGTGTCCTTAG
TCAATGATGGCCCAGTGACCTTTAATCTGCAGGTGTAA

Upstream 100 bases:

>100_bases
ATAAGGACGAAGCGAGTACGAAAACTTAAGTTTTTGCCGATTAATTGCGGTAATAGGTTTTATGTTGGCAATATAACCAT
ATCAATATAAAGGAAAAGTT

Downstream 100 bases:

>100_bases
CTTCTATCGAGATGTTTATCTTGGGGCCCCGGTGATTGAGTATTAGACATAATCAATGTCGCTTGTACCAAGAGGGAGTA
TTAAGGGAAATGCGCATGGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTTETGQFGADMQVSLVNDGPVTFNLQV

Sequences:

>Translated_145_residues
MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTTETGQFGADMQVSLVNDGPVTFNLQV
>Mature_145_residues
MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENGKMNLNLEQVGGSLLVVSQFT
LAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTTETGQFGADMQVSLVNDGPVTFNLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=152, Percent_Identity=38.8157894736842, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=64.1379310344827, Blast_Score=194, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=39.0728476821192, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=42.4657534246575, Blast_Score=111, Evalue=6e-26,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=37.6712328767123, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 15734; Mature: 15734

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENG
CHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTT
EEEEEHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ETGQFGADMQVSLVNDGPVTFNLQV
CCCCCCCCEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSRASVVVDNQTLGSIDKGLLVLLGVEREDNREKMEKLATKVMSYRVFSDENG
CHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEEECCCC
KMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALTLYEEFVAFCRDKGVTT
EEEEEHHHHCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ETGQFGADMQVSLVNDGPVTFNLQV
CCCCCCCCEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA