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The map label for this gene is atoS [H]

Identifier: 120596909

GI number: 120596909

Start: 93034

End: 95157

Strand: Direct

Name: atoS [H]

Synonym: Sputw3181_0076

Alternate gene names: 120596909

Gene position: 93034-95157 (Clockwise)

Preceding gene: 120596908

Following gene: 120596912

Centisome position: 1.98

GC content: 44.02

Gene sequence:

>2124_bases
GTGTCTTTCTTTACTCACTTTTTTGGTGTCAGTTGGCAGCAAATGCAGGCCAAGGTGCGTTATCGCATATTAATCCTTAC
CTTATTGCCTATTTTACTGACGCTGGTGAGTTTAGTTTTTATCACCATTTACTGGAACATTAGTTACACAGGTAAGCAGC
TATTTATGAAGGTAAAAGCTGACTTAGCAGTGGCTGAAAATACCCTACAACAAGTGCAAGTTCGTCAGGAAAAACAGCTC
GAAAAGGTGATGACATCTTGGACTTTTCAAAATGATTTTCGCCCTATATTGAACGGAGAAATGAATCATAGGGCCAATAT
TGATGCTTTTCTGAATGAACAAAAACAACTGCTTAATCTCGATTATCTACGTTTAGTCAGTGTCTCAGAGGCGGCGACAG
ATCCCGATTTACGCTTGATTTTACCCAAAATGGGCGGTCTATTGCCTTATTCTGGCCTGATGGTGTTATCGCCGGAGCGT
TTAGCTCGAATTGATCCTGAGCTAGCCGTTACCGCGAGTATTCCCATTGTTGCAACCTTACGGGCCCAAAATCCGGATAA
AGGGGTGGAAGGGCGTGGTTTACTCAGTCGTAGTTTACTGCCAGTACCTGATTTAGCGGGTAAGGTTGCTTGGTATTTGG
ATGGTGGCATCTTATTTAACCGCGATACACGCATCGTTGATCATATTCGGGATTTGGTATACGACAAAGGCACGCTCCCT
GAGCGTTCAATTGGTACGGTTACCATTTTTTTAGATAACATTCGTATTTCTACTAATGTGCCGTTGCACTTTTTTCCTCA
AGGCAATGAAACTCAAGGTCGAGCTTTAGGTAGTTTAGTGTCTGAGGAGGTACGTGAGAAAGTGCTCAATCGTGGTGAGC
TATGGGTGGATCGTGCCTTTGTGTTCAATGATTGGTTTATTTCTGCCTATGCGCCTTTGGAGGATATTCGAGGCCAGCGA
GTGGGCATGATCTACACAGGGTTCTCTGAGTCACCCTTTATTCATAATTATCTTTTGAATATCATTGAGCTAGGCACAAT
TCTGATGTTGGTGCTACTCGTATCAGGTTTACTGGTTTATCGCGGGGCCTATAGCCTGTTGCTACCGATAGAACGGATCC
ATCATGTCGTGCAGGCGGTGCAGTCTGGGCGCAATATTCGTATCGGCGCCTTAGGTTTGGACAGAGAAAACGAATTATCG
AATTTGGCCGAGCAGTTTGATCGTATGCTCGACTTATTGCAACGTCGTAATGCACAGATCCAATCTGCTGCTGAGCAGCT
TGAGATGAAGGTCGAAGAACGTACCCGTAGTCTTCAGGACAAAACCTTAGAGTTAGAACGTAACGTCGCACTGCTAAATG
AAACCCGCCAGCAGCTTGTGACTAACGAAAAACTCACCGCACTCGGTGAGTTAACCGCAGGCATAGCCCATGAAATTAAT
AATCCCACCGCGGTTATTCTCGGTAATATGGAGCTAATGCGCTACGAGCTTGGGGATAATGCGGACCTCGTTAAAGAAGA
AATTGATTTAGTCATCCAGCAAGTGATGCGTATCAGCACCATTATTCGCAGCTTATTACAGTACAGCCGTCCCGGTGAAT
TTAATGCGCCACTAGAAATGCAGTCTATTACTCCCATTATTGAAGAGACTATGGTGCTGGTTCGTCATTCGATTAAAAAA
CAAGAAGTTATCTTGATCACTGAGTTGAGTGCGACTTGCCTTGTGCAAGTCAATCGACCGCAGCTATTGCAGGTCTTGAT
TAATTTGGTGGTAAACGCAGCGCATGCAATGGACGGTAAAGGTCGTATTTGGGTAAGGACTTACGACTGGTTGCAACAAG
ATGTGCCCATAGGCGTTAAAATTGAGGTTGAAGATGAAGGCTCTGGAATTGCGCCTGAGTTATTGGGTCGAATTTTTGAC
CCATTTTATACCACCCGTAAGGATGGTACTGGGTTAGGGCTTTCTTTAAGTTATGGAATTATAAAACGAATTGGTGGGAC
AATAGAGGTCAGTTCAACCTTAGGTAAAGGTACTGTATTCACGATTGGTTTATACCATGAGGCGAAAGAAGAGCAGGAGA
ATAATCCCTATGACGGATTACATTTCTCTGGATCTGAAATTTAA

Upstream 100 bases:

>100_bases
AATAAATCTGCGGCAGCGAGAGACTTAGGTGTTTCTCGTAAAACCTTAGATCGTAAATATAAAGAGTGGTTTGGCTTAAG
CGACGAACAGGAGTCTTAGG

Downstream 100 bases:

>100_bases
GCAAAAAAAAGCCGGATGATGAGTCCGGCCACAAAAGAGTGTGTGAGCAATGTCGTGCTTGCAAACTCAGGAGCACTTTA
ACAACTTCAGATTACCAGTC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 707; Mature: 706

Protein sequence:

>707_residues
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLAVAENTLQQVQVRQEKQL
EKVMTSWTFQNDFRPILNGEMNHRANIDAFLNEQKQLLNLDYLRLVSVSEAATDPDLRLILPKMGGLLPYSGLMVLSPER
LARIDPELAVTASIPIVATLRAQNPDKGVEGRGLLSRSLLPVPDLAGKVAWYLDGGILFNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNIRISTNVPLHFFPQGNETQGRALGSLVSEEVREKVLNRGELWVDRAFVFNDWFISAYAPLEDIRGQR
VGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLLPIERIHHVVQAVQSGRNIRIGALGLDRENELS
NLAEQFDRMLDLLQRRNAQIQSAAEQLEMKVEERTRSLQDKTLELERNVALLNETRQQLVTNEKLTALGELTAGIAHEIN
NPTAVILGNMELMRYELGDNADLVKEEIDLVIQQVMRISTIIRSLLQYSRPGEFNAPLEMQSITPIIEETMVLVRHSIKK
QEVILITELSATCLVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWLQQDVPIGVKIEVEDEGSGIAPELLGRIFD
PFYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTVFTIGLYHEAKEEQENNPYDGLHFSGSEI

Sequences:

>Translated_707_residues
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLAVAENTLQQVQVRQEKQL
EKVMTSWTFQNDFRPILNGEMNHRANIDAFLNEQKQLLNLDYLRLVSVSEAATDPDLRLILPKMGGLLPYSGLMVLSPER
LARIDPELAVTASIPIVATLRAQNPDKGVEGRGLLSRSLLPVPDLAGKVAWYLDGGILFNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNIRISTNVPLHFFPQGNETQGRALGSLVSEEVREKVLNRGELWVDRAFVFNDWFISAYAPLEDIRGQR
VGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLLPIERIHHVVQAVQSGRNIRIGALGLDRENELS
NLAEQFDRMLDLLQRRNAQIQSAAEQLEMKVEERTRSLQDKTLELERNVALLNETRQQLVTNEKLTALGELTAGIAHEIN
NPTAVILGNMELMRYELGDNADLVKEEIDLVIQQVMRISTIIRSLLQYSRPGEFNAPLEMQSITPIIEETMVLVRHSIKK
QEVILITELSATCLVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWLQQDVPIGVKIEVEDEGSGIAPELLGRIFD
PFYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTVFTIGLYHEAKEEQENNPYDGLHFSGSEI
>Mature_706_residues
SFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKADLAVAENTLQQVQVRQEKQLE
KVMTSWTFQNDFRPILNGEMNHRANIDAFLNEQKQLLNLDYLRLVSVSEAATDPDLRLILPKMGGLLPYSGLMVLSPERL
ARIDPELAVTASIPIVATLRAQNPDKGVEGRGLLSRSLLPVPDLAGKVAWYLDGGILFNRDTRIVDHIRDLVYDKGTLPE
RSIGTVTIFLDNIRISTNVPLHFFPQGNETQGRALGSLVSEEVREKVLNRGELWVDRAFVFNDWFISAYAPLEDIRGQRV
GMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVYRGAYSLLLPIERIHHVVQAVQSGRNIRIGALGLDRENELSN
LAEQFDRMLDLLQRRNAQIQSAAEQLEMKVEERTRSLQDKTLELERNVALLNETRQQLVTNEKLTALGELTAGIAHEINN
PTAVILGNMELMRYELGDNADLVKEEIDLVIQQVMRISTIIRSLLQYSRPGEFNAPLEMQSITPIIEETMVLVRHSIKKQ
EVILITELSATCLVQVNRPQLLQVLINLVVNAAHAMDGKGRIWVRTYDWLQQDVPIGVKIEVEDEGSGIAPELLGRIFDP
FYTTRKDGTGLGLSLSYGIIKRIGGTIEVSSTLGKGTVFTIGLYHEAKEEQENNPYDGLHFSGSEI

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=36.0869565217391, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=34.9557522123894, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081816, Length=292, Percent_Identity=29.4520547945205, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=235, Percent_Identity=31.4893617021277, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=27.9816513761468, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=23.5507246376812, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1789808, Length=209, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=126, Percent_Identity=34.1269841269841, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=258, Percent_Identity=26.3565891472868, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79750; Mature: 79618

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHH
DLAVAENTLQQVQVRQEKQLEKVMTSWTFQNDFRPILNGEMNHRANIDAFLNEQKQLLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHCC
DYLRLVSVSEAATDPDLRLILPKMGGLLPYSGLMVLSPERLARIDPELAVTASIPIVATL
HHHHEEEHHHCCCCCCCEEEECHHCCCCCCCCEEEECHHHHHHCCCCEEEEECCCEEEEE
RAQNPDKGVEGRGLLSRSLLPVPDLAGKVAWYLDGGILFNRDTRIVDHIRDLVYDKGTLP
ECCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNIRISTNVPLHFFPQGNETQGRALGSLVSEEVREKVLNRGELWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
VFNDWFISAYAPLEDIRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVY
EEECCHHEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLLPIERIHHVVQAVQSGRNIRIGALGLDRENELSNLAEQFDRMLDLLQRRNAQI
HCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QSAAEQLEMKVEERTRSLQDKTLELERNVALLNETRQQLVTNEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPTAVILGNMELMRYELGDNADLVKEEIDLVIQQVMRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEH
QSITPIIEETMVLVRHSIKKQEVILITELSATCLVQVNRPQLLQVLINLVVNAAHAMDGK
HHCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCC
GRIWVRTYDWLQQDVPIGVKIEVEDEGSGIAPELLGRIFDPFYTTRKDGTGLGLSLSYGI
CEEEEEEHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCEEEHHHHH
IKRIGGTIEVSSTLGKGTVFTIGLYHEAKEEQENNPYDGLHFSGSEI
HHHCCCCEEEECCCCCCEEEEEEEHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFFTHFFGVSWQQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGKQLFMKVKA
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHH
DLAVAENTLQQVQVRQEKQLEKVMTSWTFQNDFRPILNGEMNHRANIDAFLNEQKQLLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHCC
DYLRLVSVSEAATDPDLRLILPKMGGLLPYSGLMVLSPERLARIDPELAVTASIPIVATL
HHHHEEEHHHCCCCCCCEEEECHHCCCCCCCCEEEECHHHHHHCCCCEEEEECCCEEEEE
RAQNPDKGVEGRGLLSRSLLPVPDLAGKVAWYLDGGILFNRDTRIVDHIRDLVYDKGTLP
ECCCCCCCCCCCCCHHCCCCCCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNIRISTNVPLHFFPQGNETQGRALGSLVSEEVREKVLNRGELWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
VFNDWFISAYAPLEDIRGQRVGMIYTGFSESPFIHNYLLNIIELGTILMLVLLVSGLLVY
EEECCHHEECCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLLPIERIHHVVQAVQSGRNIRIGALGLDRENELSNLAEQFDRMLDLLQRRNAQI
HCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
QSAAEQLEMKVEERTRSLQDKTLELERNVALLNETRQQLVTNEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPTAVILGNMELMRYELGDNADLVKEEIDLVIQQVMRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEH
QSITPIIEETMVLVRHSIKKQEVILITELSATCLVQVNRPQLLQVLINLVVNAAHAMDGK
HHCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCC
GRIWVRTYDWLQQDVPIGVKIEVEDEGSGIAPELLGRIFDPFYTTRKDGTGLGLSLSYGI
CEEEEEEHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCHHHCCCCCCCCCEEEHHHHH
IKRIGGTIEVSSTLGKGTVFTIGLYHEAKEEQENNPYDGLHFSGSEI
HHHCCCCEEEECCCCCCEEEEEEEHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]