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The map label for this gene is aroE

Identifier: 120596865

GI number: 120596865

Start: 36350

End: 37198

Strand: Direct

Name: aroE

Synonym: Sputw3181_0032

Alternate gene names: 120596865

Gene position: 36350-37198 (Clockwise)

Preceding gene: 120596863

Following gene: 120596866

Centisome position: 0.77

GC content: 49.71

Gene sequence:

>849_bases
ATGACAGACAAATACGCAGTGTTTGGCAATCCAATTAGCCACAGTAAATCGCCGTTCATTCATGGACAATTTGCTGCGCC
CACCCAAGAGTTATTAACCTATGAAGCCATTCTTGCTCCGGTCGATGGTTTTGAAGCCTCACTGACGGCGTTTTTCAATG
CGGGCGGCAAGGGCGCGAATGTGACAGTGCCTTTTAAGGAGCAAGCTTTTGCGCTGTGTGACAGTCTCAGCCCAGAGGCC
AAGCTTGCCGGCGCGGTAAACACCTTAAGTTTATTGGCCGATGGCACTATTCGCGGTGATAACACCGATGGTTTAGGGCT
GGTGGCTGATCTCATCGCTAACTTAGGCAGCCTGCAAGGTAAGCGCGTGTTACTTATAGGTGCTGGTGGTGCGGCGCGCG
GTTGTATTCTGCCATTATTAAATGCGGGAATTGCGCAGCTAACGATTAGCAATCGCACTCACACTAAGGCACAGCTTCTG
GTCGATATCTTTACTTCGGTGGATAACGGTGCTTTCGCAAATAGAGTCACCGCCGTAGAAATGAATGAGCTTGTGGGCGA
ATTCGATATCATTATTAACTCAACTTCGGCTAGCCTTGCGGGCGAGTTGCCACCCGTGCCAGCGCATATCATTACCCCTC
AAACTGTCTGCTATGACATGATGTATGGTGCCTCAGTTACCGCTTTTAACCAATGGGCGCTATCCCAAGGTGCAGCTAAG
GTTATTGATGGACTCGGTATGTTAGTCGGACAAGCCGCTAAAAGCTTTACCCTATGGCGAGGTGTTGAGCCAGATACTCA
AGTGGTGTTGACTCTTTTGCGGGACAAATTAAAGGCTGAGCCTAAGTAG

Upstream 100 bases:

>100_bases
GCGCATTATAGCGTGAAATTTAGTTGAGCATAATTCGTCTTGCCTAGGCTCAAAAGCGCGGTAGACTGCAAAGCCATTGA
ACCTAAAATTTAATATCGCT

Downstream 100 bases:

>100_bases
GAAGCATGAATCAAAGTATTCTTTTCCCCGAACTGCAATATTGGGACGACGCCCACAAGCGAGTCTGCTTTATCGCGCAG
TCACAAGGGATGAACATCAA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSLSPEA
KLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQGKRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLL
VDIFTSVDNGAFANRVTAVEMNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAK
VIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK

Sequences:

>Translated_282_residues
MTDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSLSPEA
KLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQGKRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLL
VDIFTSVDNGAFANRVTAVEMNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAK
VIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK
>Mature_281_residues
TDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSLSPEAK
LAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQGKRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLLV
DIFTSVDNGAFANRVTAVEMNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAKV
IDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=51.4388489208633, Blast_Score=269, Evalue=1e-73,
Organism=Escherichia coli, GI1787983, Length=281, Percent_Identity=30.2491103202847, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=276, Percent_Identity=30.0724637681159, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29515; Mature: 29384

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGAN
CCCCEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCE
VTVPFKEQAFALCDSLSPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQG
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCC
KRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLLVDIFTSVDNGAFANRVTAVE
CEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHCEEEEE
MNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAK
HHHHHCEEEEEEECCCCHHCCCCCCCCCEEECCHHHHHHHHHCCEEHHHHHHHHHCCHHH
VIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK
HHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDKYAVFGNPISHSKSPFIHGQFAAPTQELLTYEAILAPVDGFEASLTAFFNAGGKGAN
CCCEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCE
VTVPFKEQAFALCDSLSPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQG
EEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHCCCC
KRVLLIGAGGAARGCILPLLNAGIAQLTISNRTHTKAQLLVDIFTSVDNGAFANRVTAVE
CEEEEEECCCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHCEEEEE
MNELVGEFDIIINSTSASLAGELPPVPAHIITPQTVCYDMMYGASVTAFNQWALSQGAAK
HHHHHCEEEEEEECCCCHHCCCCCCCCCEEECCHHHHHHHHHCCEEHHHHHHHHHCCHHH
VIDGLGMLVGQAAKSFTLWRGVEPDTQVVLTLLRDKLKAEPK
HHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA