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The map label for this gene is ribE [H]

Identifier: 161986628

GI number: 161986628

Start: 3870607

End: 3871317

Strand: Direct

Name: ribE [H]

Synonym: Ping_3144

Alternate gene names: 161986628

Gene position: 3870607-3871317 (Clockwise)

Preceding gene: 119946749

Following gene: 119946758

Centisome position: 84.89

GC content: 34.32

Gene sequence:

>711_bases
ATGTTTACAGGAATAGTTCAGTCTATAGCGAATATTGCTGACGTTAGTGATGAAAATGGTATTAGAACGTTTATTATCGA
TTTCAAGGTTGGGTTTTGTAATAATTTAGAAATTGGGGCGAGTGTCGCTGTTGATGGTGTTTGTTTAACAGTAACAGAAA
TAATTTCAGAGGTTAGAGTTAAATTTGATATTATTTTACAAAGTCTTTTGATCACCACTTTAAGTGAGTATGAAAACGAT
TCATATATAAACGTCGAAAGAGCTGCAAAGGATGGAGCTGAAATTGGTGGGCATCCATTATCTGGTCATGTTGATTTTAA
GACGCCAATTGAAAAAATCATTCAGATTGAAGATAATTATTGTATTCGTTTAAGTTTATCGAATGAGTGGAGTCGTTACA
TTTTCCCTAAGGGGTACATTGCACTAAATGGTGCAAGTTTGACTGTTTCTCAAGTAAATAAGCAAGAGGGCTGGTTTGAA
GTTTGGTTAATTCCAGAAACTCGTAGAATGACTGTATTCGAAGACAAGATTGTCGGAGATAATATCAATGTTGAAATTGA
GCGTGGGACTCAGGTTATAGTAGATACTGTAAGAGATACACTTCATGAAAGTTTAGGCCCTTTACTTCCATTGTTCGAAA
AGTTACTAACAGAACAAGGTATTGACGTTAATTCATTAGGTCATAGCCCTGAATTACTTATAAAAAAATAG

Upstream 100 bases:

>100_bases
ATTTAATAGATATTAAATGTTACTTTTGGCACATGCAGAAATTTTCTGCTTAATAAATCGGTTCGTTCTATATCTTTAAT
TTTTCAAAATGAGAGAGTTT

Downstream 100 bases:

>100_bases
AACTAATAACACGCTATTATTTACCATAACGCCCGTTATATGCATTTTTAGAGGCTACCAGATGGTAGCCTCTGTTGTGT
ATGGCTGTAAATTTCCCTAG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MFTGIVQSIANIADVSDENGIRTFIIDFKVGFCNNLEIGASVAVDGVCLTVTEIISEVRVKFDIILQSLLITTLSEYEND
SYINVERAAKDGAEIGGHPLSGHVDFKTPIEKIIQIEDNYCIRLSLSNEWSRYIFPKGYIALNGASLTVSQVNKQEGWFE
VWLIPETRRMTVFEDKIVGDNINVEIERGTQVIVDTVRDTLHESLGPLLPLFEKLLTEQGIDVNSLGHSPELLIKK

Sequences:

>Translated_236_residues
MFTGIVQSIANIADVSDENGIRTFIIDFKVGFCNNLEIGASVAVDGVCLTVTEIISEVRVKFDIILQSLLITTLSEYEND
SYINVERAAKDGAEIGGHPLSGHVDFKTPIEKIIQIEDNYCIRLSLSNEWSRYIFPKGYIALNGASLTVSQVNKQEGWFE
VWLIPETRRMTVFEDKIVGDNINVEIERGTQVIVDTVRDTLHESLGPLLPLFEKLLTEQGIDVNSLGHSPELLIKK
>Mature_236_residues
MFTGIVQSIANIADVSDENGIRTFIIDFKVGFCNNLEIGASVAVDGVCLTVTEIISEVRVKFDIILQSLLITTLSEYEND
SYINVERAAKDGAEIGGHPLSGHVDFKTPIEKIIQIEDNYCIRLSLSNEWSRYIFPKGYIALNGASLTVSQVNKQEGWFE
VWLIPETRRMTVFEDKIVGDNINVEIERGTQVIVDTVRDTLHESLGPLLPLFEKLLTEQGIDVNSLGHSPELLIKK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=202, Percent_Identity=41.0891089108911, Blast_Score=140, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319733, Length=214, Percent_Identity=29.4392523364486, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 26341; Mature: 26341

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVQSIANIADVSDENGIRTFIIDFKVGFCNNLEIGASVAVDGVCLTVTEIISEVRV
CCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHH
KFDIILQSLLITTLSEYENDSYINVERAAKDGAEIGGHPLSGHVDFKTPIEKIIQIEDNY
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHCCCCCCCCCCCCHHHHHHHHEECCCE
CIRLSLSNEWSRYIFPKGYIALNGASLTVSQVNKQEGWFEVWLIPETRRMTVFEDKIVGD
EEEEEECCCCCEEECCCCEEEEECCEEEEECCCCCCCCEEEEEECCCCCEEEEECEEECC
NINVEIERGTQVIVDTVRDTLHESLGPLLPLFEKLLTEQGIDVNSLGHSPELLIKK
CCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCCCCEEEEC
>Mature Secondary Structure
MFTGIVQSIANIADVSDENGIRTFIIDFKVGFCNNLEIGASVAVDGVCLTVTEIISEVRV
CCHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHH
KFDIILQSLLITTLSEYENDSYINVERAAKDGAEIGGHPLSGHVDFKTPIEKIIQIEDNY
HHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHCCCCCCCCCCCCHHHHHHHHEECCCE
CIRLSLSNEWSRYIFPKGYIALNGASLTVSQVNKQEGWFEVWLIPETRRMTVFEDKIVGD
EEEEEECCCCCEEECCCCEEEEECCEEEEECCCCCCCCEEEEEECCCCCEEEEECEEECC
NINVEIERGTQVIVDTVRDTLHESLGPLLPLFEKLLTEQGIDVNSLGHSPELLIKK
CCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]