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The map label for this gene is dnaA

Identifier: 119947308

GI number: 119947308

Start: 4524210

End: 4525586

Strand: Direct

Name: dnaA

Synonym: Ping_3714

Alternate gene names: 119947308

Gene position: 4524210-4525586 (Clockwise)

Preceding gene: 119947307

Following gene: 119947309

Centisome position: 99.22

GC content: 40.89

Gene sequence:

>1377_bases
ATGTCCCTGGCAATTTGGCAAGAGTGCCTAGCACAATTAAAAGATGAACTGTCAGCCGGAGACTTTAGTACTTGGTTACG
TCCTCTTCAAGCAGATTTTAATCATTCAACCCTGTCACTTTATTCTCCTAATAAATATACCAGCGAATGGGTGCGTAATA
AATACATGGCGACGATTGAAGATAAGGTCCAACAACTTGTTAATCAGGAAAATCCTAATCACTCGGTGAAGATTCGTTTA
ATGGTGGGTAATGTTAGTTCTGTTGAAAAAAAACCAGCAAAGCAAATCCCTACCCAGGCACCTCTTACCAATCAACCTTG
GGAAGGCGAAAGCAAAGCCCATAGAGTTCCTCACAAAAGTAATTTAATAAAAAAATACACTTTTGATAATTTTGTTGAAG
GTAAATCAAATAATTTCGCTATCGCAACAACCCAGCAAATAGCTGAAAACCCGGGTGATGTATACAATCCCCTGTTTTTA
TATGCGCATCCAGGTTTAGGTAAGACACATTTATTACATGCTGTTGGCAATGCCATTCTCGCAGAAAATCCTGAGAGTAA
AGTGGTCTATATCCGCTCAGAGCGTTTTGTGCAGGATATGATTAACTCGATCCGTAACAATACTATCGAACAGTTTAAAG
AATATTATGCATCACTTGATGCTCTGCTTATTGATGATATTCATTTCTTTGCCGGTAAAGATCGCTCTCAAGAAGTACTT
TTCCAAACCTTTAATTCTATGTTGGATGCGCATCAACAGGTTATTTTAACCAGTGACCGTTTTCCCAAGGAAATTGAAGG
TATTGACGAGCGTTTACGAACCCGTTTTGGTTGGGGATTATCCATTCCCATTGATCCGCCTGAATTGGAAACACGGGTTG
CAATTTTAATCACTAAAGCCGAAGAACGCGGCCTAAAACTGCCCGATGATGTGGCTTTCTTTATTGCTAAGCGCTTAACT
ATTACCGACGTGCGTGTTTTAGAAGGGGCGATTGCTAATATTTCTGCAAAAGCACAATTCACCGGTCAAGGTATAACGAT
ATCTCTAGTACAAGATGCGCTACGCGATATGCTGGCGGTGCATACCAAACAGACGACTATTGACAATATTCAAAAAATAG
TCGCTCAGCATTATCGTATTAAAATATCCGATATGTCTTCAAAACGCCGTACCCGGACCGTAGCCCGCCCTCGTCAAATT
GCCATGGCATTAGCTAAAGAGTTAACTCAACATAGCCTGCCGGAGATTGGAGAGGCATTTGGCGGACGAGATCACACCAC
GGTTTTACATGCGTGCAGAAAAGTCCAAGAGTTACGTCGAGAAAATAATGATATTCAAGAGGATTATAAAATTCTGATCC
GCACACTTTCGATGTAG

Upstream 100 bases:

>100_bases
ACACAAGGATCTTTTTTACTTATTTATGCAAGGATCTTGTGGCGGAAAACAGATCTTAGCGGTAGAATTATGCGCCCGAA
TTTAATAACTGGAGTTAGTG

Downstream 100 bases:

>100_bases
ACAAAGCAGATCTGATCCAGCCCGTCAAAACTGTTGATAATTTATTTGGATTAAAAACAGAGCGAGCAACTCGTTAAGTA
ATTTAAAGGATAAATGGCTT

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSLAIWQECLAQLKDELSAGDFSTWLRPLQADFNHSTLSLYSPNKYTSEWVRNKYMATIEDKVQQLVNQENPNHSVKIRL
MVGNVSSVEKKPAKQIPTQAPLTNQPWEGESKAHRVPHKSNLIKKYTFDNFVEGKSNNFAIATTQQIAENPGDVYNPLFL
YAHPGLGKTHLLHAVGNAILAENPESKVVYIRSERFVQDMINSIRNNTIEQFKEYYASLDALLIDDIHFFAGKDRSQEVL
FQTFNSMLDAHQQVILTSDRFPKEIEGIDERLRTRFGWGLSIPIDPPELETRVAILITKAEERGLKLPDDVAFFIAKRLT
ITDVRVLEGAIANISAKAQFTGQGITISLVQDALRDMLAVHTKQTTIDNIQKIVAQHYRIKISDMSSKRRTRTVARPRQI
AMALAKELTQHSLPEIGEAFGGRDHTTVLHACRKVQELRRENNDIQEDYKILIRTLSM

Sequences:

>Translated_458_residues
MSLAIWQECLAQLKDELSAGDFSTWLRPLQADFNHSTLSLYSPNKYTSEWVRNKYMATIEDKVQQLVNQENPNHSVKIRL
MVGNVSSVEKKPAKQIPTQAPLTNQPWEGESKAHRVPHKSNLIKKYTFDNFVEGKSNNFAIATTQQIAENPGDVYNPLFL
YAHPGLGKTHLLHAVGNAILAENPESKVVYIRSERFVQDMINSIRNNTIEQFKEYYASLDALLIDDIHFFAGKDRSQEVL
FQTFNSMLDAHQQVILTSDRFPKEIEGIDERLRTRFGWGLSIPIDPPELETRVAILITKAEERGLKLPDDVAFFIAKRLT
ITDVRVLEGAIANISAKAQFTGQGITISLVQDALRDMLAVHTKQTTIDNIQKIVAQHYRIKISDMSSKRRTRTVARPRQI
AMALAKELTQHSLPEIGEAFGGRDHTTVLHACRKVQELRRENNDIQEDYKILIRTLSM
>Mature_457_residues
SLAIWQECLAQLKDELSAGDFSTWLRPLQADFNHSTLSLYSPNKYTSEWVRNKYMATIEDKVQQLVNQENPNHSVKIRLM
VGNVSSVEKKPAKQIPTQAPLTNQPWEGESKAHRVPHKSNLIKKYTFDNFVEGKSNNFAIATTQQIAENPGDVYNPLFLY
AHPGLGKTHLLHAVGNAILAENPESKVVYIRSERFVQDMINSIRNNTIEQFKEYYASLDALLIDDIHFFAGKDRSQEVLF
QTFNSMLDAHQQVILTSDRFPKEIEGIDERLRTRFGWGLSIPIDPPELETRVAILITKAEERGLKLPDDVAFFIAKRLTI
TDVRVLEGAIANISAKAQFTGQGITISLVQDALRDMLAVHTKQTTIDNIQKIVAQHYRIKISDMSSKRRTRTVARPRQIA
MALAKELTQHSLPEIGEAFGGRDHTTVLHACRKVQELRRENNDIQEDYKILIRTLSM

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=471, Percent_Identity=57.5371549893843, Blast_Score=568, Evalue=1e-163,
Organism=Escherichia coli, GI226510964, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_PSYIN (A1T0X4)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944988.1
- ProteinModelPortal:   A1T0X4
- STRING:   A1T0X4
- GeneID:   4623394
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3714
- eggNOG:   COG0593
- HOGENOM:   HBG695666
- OMA:   CHTLNAL
- PhylomeDB:   A1T0X4
- BioCyc:   PING357804:PING_3714-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 52115; Mature: 51984

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIWQECLAQLKDELSAGDFSTWLRPLQADFNHSTLSLYSPNKYTSEWVRNKYMATIE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
DKVQQLVNQENPNHSVKIRLMVGNVSSVEKKPAKQIPTQAPLTNQPWEGESKAHRVPHKS
HHHHHHHCCCCCCCEEEEEEEECCCHHHHHCHHHHCCCCCCCCCCCCCCCCHHHCCCCHH
NLIKKYTFDNFVEGKSNNFAIATTQQIAENPGDVYNPLFLYAHPGLGKTHLLHAVGNAIL
HHHHHHCHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
AENPESKVVYIRSERFVQDMINSIRNNTIEQFKEYYASLDALLIDDIHFFAGKDRSQEVL
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
FQTFNSMLDAHQQVILTSDRFPKEIEGIDERLRTRFGWGLSIPIDPPELETRVAILITKA
HHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEEEH
EERGLKLPDDVAFFIAKRLTITDVRVLEGAIANISAKAQFTGQGITISLVQDALRDMLAV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEHHHHHHHHHHHHHH
HTKQTTIDNIQKIVAQHYRIKISDMSSKRRTRTVARPRQIAMALAKELTQHSLPEIGEAF
HHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GGRDHTTVLHACRKVQELRRENNDIQEDYKILIRTLSM
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLAIWQECLAQLKDELSAGDFSTWLRPLQADFNHSTLSLYSPNKYTSEWVRNKYMATIE
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
DKVQQLVNQENPNHSVKIRLMVGNVSSVEKKPAKQIPTQAPLTNQPWEGESKAHRVPHKS
HHHHHHHCCCCCCCEEEEEEEECCCHHHHHCHHHHCCCCCCCCCCCCCCCCHHHCCCCHH
NLIKKYTFDNFVEGKSNNFAIATTQQIAENPGDVYNPLFLYAHPGLGKTHLLHAVGNAIL
HHHHHHCHHHHHCCCCCCEEEEEHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
AENPESKVVYIRSERFVQDMINSIRNNTIEQFKEYYASLDALLIDDIHFFAGKDRSQEVL
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
FQTFNSMLDAHQQVILTSDRFPKEIEGIDERLRTRFGWGLSIPIDPPELETRVAILITKA
HHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEEEH
EERGLKLPDDVAFFIAKRLTITDVRVLEGAIANISAKAQFTGQGITISLVQDALRDMLAV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEHHHHHHHHHHHHHH
HTKQTTIDNIQKIVAQHYRIKISDMSSKRRTRTVARPRQIAMALAKELTQHSLPEIGEAF
HHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GGRDHTTVLHACRKVQELRRENNDIQEDYKILIRTLSM
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA