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The map label for this gene is mauR [H]

Identifier: 119947262

GI number: 119947262

Start: 4473177

End: 4474097

Strand: Direct

Name: mauR [H]

Synonym: Ping_3660

Alternate gene names: 119947262

Gene position: 4473177-4474097 (Clockwise)

Preceding gene: 119947255

Following gene: 119947263

Centisome position: 98.1

GC content: 35.94

Gene sequence:

>921_bases
ATGCTCAATGAAAATATTACTTTAAAAAAATTACACATTTTTTTAACTTTTATGAAATGCCGCACAATGAATAAAACAGC
TGAGATGTTAAATATGAGTACTGTCAGCATACACAGAGCCATTCATTCTTTAGAAACAGAATTACAATGCCCCTTATTCC
AACAACAAGGACGACTTTTGTCCCCGTTAGACAGTGCAAAAACATTAGAGATAGAAGCAAAAATATTATTAAAGCAATTA
GGGAGGACTATTTCAGAGACACAAGAAACAGCTGGTATTTTTTCTGCTCATTTTAAGCTTGGATCTATCTATTCATTAAC
TTTTAATTCCATCCCTGCATTGATAACCAGCATGAAAAAACAGGATAAGAAACTTGAAATTGAGTTAACGACCTCCTCTA
ATAAATATTTATTCAAGAAATTAACGGCCTTGGAGTTAGATGTCATTGTTGTCTCTTTAGACGCGCCACTGCTTGATCCA
TCATTAATTTTCTTTCCTTTATTTGAGGACCACTTAGCGCTTGCCGTTCCGGTGAATGACCCCCTTGCGTCTTATTCCAG
CATTGCCTTGGCGGATATAAAAAATTGCCCTTTTGTGATGCTCAGTAAAGGTTTTGCCACCGCTCAAGATGTCTTAAGAA
CCTTTGAAAAAGCACAGATAAAGCCCAATGTGGTAATGGAAGTCAATGATATTTTCAGCCTTATTAGCATGGTCAGCACC
GGTCTTGGTTACAGTCTGTTACCAAACAGAATTGCGCGTATTTTAAATGACAAAGTTAAATTAATCCCACTACATGAGCA
GGACAAAATAAAACAAACTATTACTATGGTTTGCCTTGCCAGTCGCTCAAAAGAACCAAAAATATTAGCTTTTACAAAGC
AGTGCCATCTTTATGCAAAATCATTAAGAGATGCTAAATGA

Upstream 100 bases:

>100_bases
GATGTTAATTTAATGTTGTGCTTCTAACAAATCAATAACTAGCGCATCACCATCATTACTGTGAAAGTAATGATCTTAGG
TTGAAGCGAGGAAAATCAGC

Downstream 100 bases:

>100_bases
TTTTTTCTTGGCATCGGATTAGCTGCCGTTAGACTTTTTTTCAGCGCAGAATGCGACGAAAAAAAAATTCTCTCTAACCG
CATTGAAGCAGGAAAATATT

Product: transcriptional regulator, substrate-binding of LysR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MLNENITLKKLHIFLTFMKCRTMNKTAEMLNMSTVSIHRAIHSLETELQCPLFQQQGRLLSPLDSAKTLEIEAKILLKQL
GRTISETQETAGIFSAHFKLGSIYSLTFNSIPALITSMKKQDKKLEIELTTSSNKYLFKKLTALELDVIVVSLDAPLLDP
SLIFFPLFEDHLALAVPVNDPLASYSSIALADIKNCPFVMLSKGFATAQDVLRTFEKAQIKPNVVMEVNDIFSLISMVST
GLGYSLLPNRIARILNDKVKLIPLHEQDKIKQTITMVCLASRSKEPKILAFTKQCHLYAKSLRDAK

Sequences:

>Translated_306_residues
MLNENITLKKLHIFLTFMKCRTMNKTAEMLNMSTVSIHRAIHSLETELQCPLFQQQGRLLSPLDSAKTLEIEAKILLKQL
GRTISETQETAGIFSAHFKLGSIYSLTFNSIPALITSMKKQDKKLEIELTTSSNKYLFKKLTALELDVIVVSLDAPLLDP
SLIFFPLFEDHLALAVPVNDPLASYSSIALADIKNCPFVMLSKGFATAQDVLRTFEKAQIKPNVVMEVNDIFSLISMVST
GLGYSLLPNRIARILNDKVKLIPLHEQDKIKQTITMVCLASRSKEPKILAFTKQCHLYAKSLRDAK
>Mature_306_residues
MLNENITLKKLHIFLTFMKCRTMNKTAEMLNMSTVSIHRAIHSLETELQCPLFQQQGRLLSPLDSAKTLEIEAKILLKQL
GRTISETQETAGIFSAHFKLGSIYSLTFNSIPALITSMKKQDKKLEIELTTSSNKYLFKKLTALELDVIVVSLDAPLLDP
SLIFFPLFEDHLALAVPVNDPLASYSSIALADIKNCPFVMLSKGFATAQDVLRTFEKAQIKPNVVMEVNDIFSLISMVST
GLGYSLLPNRIARILNDKVKLIPLHEQDKIKQTITMVCLASRSKEPKILAFTKQCHLYAKSLRDAK

Specific function: Transcriptional regulator of the mau genes for malonate utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=256, Percent_Identity=26.953125, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788296, Length=231, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=271, Percent_Identity=20.2952029520295, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790208, Length=296, Percent_Identity=22.2972972972973, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081904, Length=212, Percent_Identity=23.5849056603774, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=250, Percent_Identity=24.4, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=23.8095238095238, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788887, Length=263, Percent_Identity=23.1939163498099, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34328; Mature: 34328

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNENITLKKLHIFLTFMKCRTMNKTAEMLNMSTVSIHRAIHSLETELQCPLFQQQGRLL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
SPLDSAKTLEIEAKILLKQLGRTISETQETAGIFSAHFKLGSIYSLTFNSIPALITSMKK
CCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHC
QDKKLEIELTTSSNKYLFKKLTALELDVIVVSLDAPLLDPSLIFFPLFEDHLALAVPVND
CCCEEEEEEEECCCCHHHHHHHHEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCC
PLASYSSIALADIKNCPFVMLSKGFATAQDVLRTFEKAQIKPNVVMEVNDIFSLISMVST
CHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
GLGYSLLPNRIARILNDKVKLIPLHEQDKIKQTITMVCLASRSKEPKILAFTKQCHLYAK
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
SLRDAK
HHCCCC
>Mature Secondary Structure
MLNENITLKKLHIFLTFMKCRTMNKTAEMLNMSTVSIHRAIHSLETELQCPLFQQQGRLL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
SPLDSAKTLEIEAKILLKQLGRTISETQETAGIFSAHFKLGSIYSLTFNSIPALITSMKK
CCCCCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHC
QDKKLEIELTTSSNKYLFKKLTALELDVIVVSLDAPLLDPSLIFFPLFEDHLALAVPVND
CCCEEEEEEEECCCCHHHHHHHHEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCC
PLASYSSIALADIKNCPFVMLSKGFATAQDVLRTFEKAQIKPNVVMEVNDIFSLISMVST
CHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
GLGYSLLPNRIARILNDKVKLIPLHEQDKIKQTITMVCLASRSKEPKILAFTKQCHLYAK
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
SLRDAK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA