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The map label for this gene is fabD [H]

Identifier: 119947256

GI number: 119947256

Start: 4466826

End: 4467749

Strand: Reverse

Name: fabD [H]

Synonym: Ping_3654

Alternate gene names: 119947256

Gene position: 4467749-4466826 (Counterclockwise)

Preceding gene: 119947257

Following gene: 119947253

Centisome position: 97.99

GC content: 43.29

Gene sequence:

>924_bases
ATGAGTCTTTTATTTACCTTTCCCGGGCAGGGTGCACAAAAACCGAACATGCTTCGAAAGCTAAATGTTAATGCGCTAAC
TCAGGGGGTTTTTGAACAAGCATCGGATATGCTCGGTTATAATGTCTTTGATTTGGACTCGCAAAGCGCACAAAAAAACA
ATAAAAATGTGCAGGTGGGACTGACGGTTTGCGCTGTTGCTTGTGTGGAATTATTAGCCAGTGAAGGTATTCAAGCGGAT
TATGTTCTGGGCTTATCGATCGGCGCATTCCCCGCCGCAATTGCCAGTAAAATAATGAGTTTTGAGCAGGGATTAAAGCT
GGTTAGTTTACGCGGAAAACTCATGTCCGAAGCTTATCCGACCGGATATGCCATGGCCGCTATTATTGGATTGCCCCTGC
ATAAAATACAAGTGTTGATTCATAGTGTTAATCAAACTCACTTACCCGTGTATCTGGCGAATATCAATACGGAATACCAA
TACATTATTTCCGGTCCAATTAGTTCATTAGAGATTATTTGTCAGCAAGCCAGACTATTGCAAGCAAGCAGCGCTAAGCT
GATGAATGTTAACGTGCCTTCTCATTGCTTGTTATTAGAAGAACAGGCGCAGTCGTTATACCAAGAAATTCAAACCGCCA
CCTTTGCACCCCCACAATCCACTTTTGTCAGTGCTAATGCGGCGCGAGTTATCTTCAAAGAAGATTTTATCAAAAAAGAT
TTAGCCTTTAATATGGCTCAACAGGTGAAGTGGTGGGAAACCGCCGCCATGCTCAATCAGAGAGGCGTTTCTATGGCTAT
CGAAATGGCACCGGGCAGTGTGCTGAGTAAATTATGTGCCGTCAGCATGCCCAGCACTCAATGTTTATCCATTGAAACTT
CATCGCTTAATAGCATTAGGGTATTAGCGGATCGTTTAAGCTAA

Upstream 100 bases:

>100_bases
TAAACCAGAAAAAATAATGGTCAAAACCAATCTGGGGCCGATTTTATGTACGGATCCCTGGTCAGCAATAACCAAAGTAT
AAGTGAGGGGAAGATCAGCA

Downstream 100 bases:

>100_bases
GAAGTTGCAGGGATTTTTAAAAGCAAAAGCTGTTCCAGTTAATGCAGTACAGTCGAAGTGTTTATAATAAAAAAGCAGTT
TTTTAAAGCTTATGTTTTAC

Product: acyl transferase region

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSLLFTFPGQGAQKPNMLRKLNVNALTQGVFEQASDMLGYNVFDLDSQSAQKNNKNVQVGLTVCAVACVELLASEGIQAD
YVLGLSIGAFPAAIASKIMSFEQGLKLVSLRGKLMSEAYPTGYAMAAIIGLPLHKIQVLIHSVNQTHLPVYLANINTEYQ
YIISGPISSLEIICQQARLLQASSAKLMNVNVPSHCLLLEEQAQSLYQEIQTATFAPPQSTFVSANAARVIFKEDFIKKD
LAFNMAQQVKWWETAAMLNQRGVSMAIEMAPGSVLSKLCAVSMPSTQCLSIETSSLNSIRVLADRLS

Sequences:

>Translated_307_residues
MSLLFTFPGQGAQKPNMLRKLNVNALTQGVFEQASDMLGYNVFDLDSQSAQKNNKNVQVGLTVCAVACVELLASEGIQAD
YVLGLSIGAFPAAIASKIMSFEQGLKLVSLRGKLMSEAYPTGYAMAAIIGLPLHKIQVLIHSVNQTHLPVYLANINTEYQ
YIISGPISSLEIICQQARLLQASSAKLMNVNVPSHCLLLEEQAQSLYQEIQTATFAPPQSTFVSANAARVIFKEDFIKKD
LAFNMAQQVKWWETAAMLNQRGVSMAIEMAPGSVLSKLCAVSMPSTQCLSIETSSLNSIRVLADRLS
>Mature_306_residues
SLLFTFPGQGAQKPNMLRKLNVNALTQGVFEQASDMLGYNVFDLDSQSAQKNNKNVQVGLTVCAVACVELLASEGIQADY
VLGLSIGAFPAAIASKIMSFEQGLKLVSLRGKLMSEAYPTGYAMAAIIGLPLHKIQVLIHSVNQTHLPVYLANINTEYQY
IISGPISSLEIICQQARLLQASSAKLMNVNVPSHCLLLEEQAQSLYQEIQTATFAPPQSTFVSANAARVIFKEDFIKKDL
AFNMAQQVKWWETAAMLNQRGVSMAIEMAPGSVLSKLCAVSMPSTQCLSIETSSLNSIRVLADRLS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=295, Percent_Identity=24.7457627118644, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787334, Length=280, Percent_Identity=30.7142857142857, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=283, Percent_Identity=28.2685512367491, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33353; Mature: 33222

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLFTFPGQGAQKPNMLRKLNVNALTQGVFEQASDMLGYNVFDLDSQSAQKNNKNVQVG
CCEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCEEEH
LTVCAVACVELLASEGIQADYVLGLSIGAFPAAIASKIMSFEQGLKLVSLRGKLMSEAYP
HHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
TGYAMAAIIGLPLHKIQVLIHSVNQTHLPVYLANINTEYQYIISGPISSLEIICQQARLL
CHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHH
QASSAKLMNVNVPSHCLLLEEQAQSLYQEIQTATFAPPQSTFVSANAARVIFKEDFIKKD
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHEEHHHHHHHHHH
LAFNMAQQVKWWETAAMLNQRGVSMAIEMAPGSVLSKLCAVSMPSTQCLSIETSSLNSIR
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCHHH
VLADRLS
HHHHHCC
>Mature Secondary Structure 
SLLFTFPGQGAQKPNMLRKLNVNALTQGVFEQASDMLGYNVFDLDSQSAQKNNKNVQVG
CEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCEEEH
LTVCAVACVELLASEGIQADYVLGLSIGAFPAAIASKIMSFEQGLKLVSLRGKLMSEAYP
HHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
TGYAMAAIIGLPLHKIQVLIHSVNQTHLPVYLANINTEYQYIISGPISSLEIICQQARLL
CHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHH
QASSAKLMNVNVPSHCLLLEEQAQSLYQEIQTATFAPPQSTFVSANAARVIFKEDFIKKD
HHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHEEHHHHHHHHHH
LAFNMAQQVKWWETAAMLNQRGVSMAIEMAPGSVLSKLCAVSMPSTQCLSIETSSLNSIR
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCEEEEEECCCCCHHH
VLADRLS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]