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The map label for this gene is cdr [H]

Identifier: 119947231

GI number: 119947231

Start: 4443766

End: 4445439

Strand: Reverse

Name: cdr [H]

Synonym: Ping_3629

Alternate gene names: 119947231

Gene position: 4445439-4443766 (Counterclockwise)

Preceding gene: 119947232

Following gene: 119947229

Centisome position: 97.5

GC content: 43.79

Gene sequence:

>1674_bases
ATGTTGAGACAACGAATGTCTAAGAAAGTATTAATTGTTGGTGGCGTTGCTGGCGGTGCATCAGCAGCAGCCCGAGCACG
TCGTTTAGATGAAAATGCACAAATTATTGTGTTTGAGCGTGGTCCGTATATCTCATTTGCTAACTGCGGTTTGCCCTATC
ATATTGGTGGTGAAATAGAGCTGCGATCAGCATTATTACTGCAAACACCTGAAAGTTTTAAAAAGCGTTTTAATGTGGAT
ATTCGCATTAAAAGTGAAGTGCTATCCATAGATAAAAAAGCTAAAACGGTCACTGTCCATAATATAGCAGCGGATACAGA
GTATACAGAATCTTATGATGCGCTTATTTTAAGCCCCGGCGCCGGTCCATTGATTCCGCCAATTGCAGGTGTGCGTAATC
ATTTAACCTATGCGCTGCGCAATGTACCGGATATGGATGCAATTATTGCCTCAATTGAAATTAACAAACCCAAGCATGCC
ACCGTATGCGGTGGTGGTTTTATCGGTTTAGAGATGGCTGAAGCATTGCGTCACCGTAAAATCAAGGTGACGATAGTTGA
ACTTGGACCACAAGTGATGGCGTCGGTTGATATAGAAATCGCTAATGTCTTACATGATGAGCTTGAGCAACATGATGTTG
AACTTAAATTAGGTAAAGCATTACAAGGGATTGCTCCATCTGCGCCAGCAGATAAATCCCTGATATTAACACTGAATGAT
GGCTCTGTTGTAGAGACTAACTTATTAATTATGGCGGTTGGGGTTAAGCCTGAAACATCGTTAGCGGTGCAGGCTGGATT
AGAAATCGGTGAACTGGGCGGCATAAAAGTAAATGCGTTTATGCAGAGCAGTGATCCGGCTATTTATGCGGTAGGCGATG
CCATTGAAGATCCTGATTTTGTAACCGGTGATGCCATCTTCGTACCGCTAGCGGGGCCTGCCAATCGTCAAGGTCGTTTG
GCGGCCAATAATATTTTTGGGGCAAAGGAAACCTATAAAAAGACACAGGGTACCGCAATTTGTAAAGTATTTGAGCTGGC
CATTGCATCGACGGGATTAAATGAAAAAACGCTGCTGCGTAAAGCCATATCATATGAAAAAGTTTATGTGCACGCATCAA
GCCATGCAGGTTATTACCCTGGCGCCCATCCGGTGACATTAAAACTGCTTTTTGATCCTGCAACAGGCCTGATTTTAGGC
GCGCAAGCGGTTGGTAAAGAGGGTGTTGATAAACGCATTGATGTTATCTCCGTTGCGCAGCGTGCCGGGTTAACTGTGTA
TGATCTGCAGGATTTAGAGCTATGTTATGCCCCTCCCTTTGGCTCAGCACGCGATGTGGTTAACCAGGCGGGATTAGTGG
CCTCTAATGTGATGAAAGGTGATGAAGTTATTTTCCATAGTGAAGATCTTGAGTCGCTTTCCGACAAACAAATATTAGTC
GATGTTCGCAGTGAATTGGAAGTGGATAATACGGGCATGATCCATGGTGCAATTAATATTCCTGTGGACGACATTCGTGC
TAATTTATGTAAACTTGATCAAAACAAAGAGATTTTAATTTACTGCCAAGTGGGCGTGCGTGGTCACGTCGCTTCGCGCT
TACTCACTAACTTAGGTTATAAAGTTAAAAACTTAAGCGGTGGTTTCAAAACGTGGAAGTTGGCAACCCGCTAG

Upstream 100 bases:

>100_bases
TAAATAAATTATAACTCGTCGATTTGTTATTCAAAAATCTAAGCTGTTGCAATAGCAAATCGGTATAACCTTTAGGTGCA
CTACACCTATTATTTTTAAC

Downstream 100 bases:

>100_bases
TGGCTTAGCCATTTATTATAATACCTAGTGCTATGATTAATGCCTACCTAGTAGGCATTAATATTCGATCAGGCGAAGCG
GGTATTTAAATGTTCAATAA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MLRQRMSKKVLIVGGVAGGASAAARARRLDENAQIIVFERGPYISFANCGLPYHIGGEIELRSALLLQTPESFKKRFNVD
IRIKSEVLSIDKKAKTVTVHNIAADTEYTESYDALILSPGAGPLIPPIAGVRNHLTYALRNVPDMDAIIASIEINKPKHA
TVCGGGFIGLEMAEALRHRKIKVTIVELGPQVMASVDIEIANVLHDELEQHDVELKLGKALQGIAPSAPADKSLILTLND
GSVVETNLLIMAVGVKPETSLAVQAGLEIGELGGIKVNAFMQSSDPAIYAVGDAIEDPDFVTGDAIFVPLAGPANRQGRL
AANNIFGAKETYKKTQGTAICKVFELAIASTGLNEKTLLRKAISYEKVYVHASSHAGYYPGAHPVTLKLLFDPATGLILG
AQAVGKEGVDKRIDVISVAQRAGLTVYDLQDLELCYAPPFGSARDVVNQAGLVASNVMKGDEVIFHSEDLESLSDKQILV
DVRSELEVDNTGMIHGAINIPVDDIRANLCKLDQNKEILIYCQVGVRGHVASRLLTNLGYKVKNLSGGFKTWKLATR

Sequences:

>Translated_557_residues
MLRQRMSKKVLIVGGVAGGASAAARARRLDENAQIIVFERGPYISFANCGLPYHIGGEIELRSALLLQTPESFKKRFNVD
IRIKSEVLSIDKKAKTVTVHNIAADTEYTESYDALILSPGAGPLIPPIAGVRNHLTYALRNVPDMDAIIASIEINKPKHA
TVCGGGFIGLEMAEALRHRKIKVTIVELGPQVMASVDIEIANVLHDELEQHDVELKLGKALQGIAPSAPADKSLILTLND
GSVVETNLLIMAVGVKPETSLAVQAGLEIGELGGIKVNAFMQSSDPAIYAVGDAIEDPDFVTGDAIFVPLAGPANRQGRL
AANNIFGAKETYKKTQGTAICKVFELAIASTGLNEKTLLRKAISYEKVYVHASSHAGYYPGAHPVTLKLLFDPATGLILG
AQAVGKEGVDKRIDVISVAQRAGLTVYDLQDLELCYAPPFGSARDVVNQAGLVASNVMKGDEVIFHSEDLESLSDKQILV
DVRSELEVDNTGMIHGAINIPVDDIRANLCKLDQNKEILIYCQVGVRGHVASRLLTNLGYKVKNLSGGFKTWKLATR
>Mature_557_residues
MLRQRMSKKVLIVGGVAGGASAAARARRLDENAQIIVFERGPYISFANCGLPYHIGGEIELRSALLLQTPESFKKRFNVD
IRIKSEVLSIDKKAKTVTVHNIAADTEYTESYDALILSPGAGPLIPPIAGVRNHLTYALRNVPDMDAIIASIEINKPKHA
TVCGGGFIGLEMAEALRHRKIKVTIVELGPQVMASVDIEIANVLHDELEQHDVELKLGKALQGIAPSAPADKSLILTLND
GSVVETNLLIMAVGVKPETSLAVQAGLEIGELGGIKVNAFMQSSDPAIYAVGDAIEDPDFVTGDAIFVPLAGPANRQGRL
AANNIFGAKETYKKTQGTAICKVFELAIASTGLNEKTLLRKAISYEKVYVHASSHAGYYPGAHPVTLKLLFDPATGLILG
AQAVGKEGVDKRIDVISVAQRAGLTVYDLQDLELCYAPPFGSARDVVNQAGLVASNVMKGDEVIFHSEDLESLSDKQILV
DVRSELEVDNTGMIHGAINIPVDDIRANLCKLDQNKEILIYCQVGVRGHVASRLLTNLGYKVKNLSGGFKTWKLATR

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=23.0769230769231, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=23.0769230769231, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=23.0769230769231, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22202629, Length=181, Percent_Identity=32.5966850828729, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI4757732, Length=181, Percent_Identity=32.5966850828729, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1789065, Length=315, Percent_Identity=27.3015873015873, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1789765, Length=327, Percent_Identity=27.217125382263, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI87082354, Length=350, Percent_Identity=26.5714285714286, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788892, Length=206, Percent_Identity=26.2135922330097, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786307, Length=307, Percent_Identity=24.4299674267101, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787352, Length=273, Percent_Identity=26.007326007326, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789915, Length=383, Percent_Identity=25.065274151436, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17559934, Length=302, Percent_Identity=23.841059602649, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24639257, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359715, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281359713, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639250, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI18543267, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639252, Length=334, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585130, Length=260, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 59851; Mature: 59851

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQRMSKKVLIVGGVAGGASAAARARRLDENAQIIVFERGPYISFANCGLPYHIGGEIE
CCCHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCEEECCCEE
LRSALLLQTPESFKKRFNVDIRIKSEVLSIDKKAKTVTVHNIAADTEYTESYDALILSPG
EEEEEEECCCHHHHHHCCEEEEEEHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEECCC
AGPLIPPIAGVRNHLTYALRNVPDMDAIIASIEINKPKHATVCGGGFIGLEMAEALRHRK
CCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCE
IKVTIVELGPQVMASVDIEIANVLHDELEQHDVELKLGKALQGIAPSAPADKSLILTLND
EEEEEEECCCHHEEEECHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCCCCEEEEEECC
GSVVETNLLIMAVGVKPETSLAVQAGLEIGELGGIKVNAFMQSSDPAIYAVGDAIEDPDF
CCEEEEEEEEEEECCCCCCCEEEECCCCEECCCCEEEEEEEECCCCEEEEECCCCCCCCE
VTGDAIFVPLAGPANRQGRLAANNIFGAKETYKKTQGTAICKVFELAIASTGLNEKTLLR
EECCEEEEECCCCCCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
KAISYEKVYVHASSHAGYYPGAHPVTLKLLFDPATGLILGAQAVGKEGVDKRIDVISVAQ
HHHCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHCCCCCCHHHHHHHHHH
RAGLTVYDLQDLELCYAPPFGSARDVVNQAGLVASNVMKGDEVIFHSEDLESLSDKQILV
HCCCEEEEECCCEEEECCCCCCHHHHHHHCCHHHHHCCCCCEEEEECCHHHHCCCCEEEE
DVRSELEVDNTGMIHGAINIPVDDIRANLCKLDQNKEILIYCQVGVRGHVASRLLTNLGY
EEHHHCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCC
KVKNLSGGFKTWKLATR
EEEECCCCCEEEEEECC
>Mature Secondary Structure
MLRQRMSKKVLIVGGVAGGASAAARARRLDENAQIIVFERGPYISFANCGLPYHIGGEIE
CCCHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCEEECCCEE
LRSALLLQTPESFKKRFNVDIRIKSEVLSIDKKAKTVTVHNIAADTEYTESYDALILSPG
EEEEEEECCCHHHHHHCCEEEEEEHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEECCC
AGPLIPPIAGVRNHLTYALRNVPDMDAIIASIEINKPKHATVCGGGFIGLEMAEALRHRK
CCCCCCCHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCEEEECCCCHHHHHHHHHHCCE
IKVTIVELGPQVMASVDIEIANVLHDELEQHDVELKLGKALQGIAPSAPADKSLILTLND
EEEEEEECCCHHEEEECHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCCCCEEEEEECC
GSVVETNLLIMAVGVKPETSLAVQAGLEIGELGGIKVNAFMQSSDPAIYAVGDAIEDPDF
CCEEEEEEEEEEECCCCCCCEEEECCCCEECCCCEEEEEEEECCCCEEEEECCCCCCCCE
VTGDAIFVPLAGPANRQGRLAANNIFGAKETYKKTQGTAICKVFELAIASTGLNEKTLLR
EECCEEEEECCCCCCCCCCEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHH
KAISYEKVYVHASSHAGYYPGAHPVTLKLLFDPATGLILGAQAVGKEGVDKRIDVISVAQ
HHHCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHCCCCCCHHHHHHHHHH
RAGLTVYDLQDLELCYAPPFGSARDVVNQAGLVASNVMKGDEVIFHSEDLESLSDKQILV
HCCCEEEEECCCEEEECCCCCCHHHHHHHCCHHHHHCCCCCEEEEECCHHHHCCCCEEEE
DVRSELEVDNTGMIHGAINIPVDDIRANLCKLDQNKEILIYCQVGVRGHVASRLLTNLGY
EEHHHCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCC
KVKNLSGGFKTWKLATR
EEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA