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The map label for this gene is coaA

Identifier: 119947224

GI number: 119947224

Start: 4438645

End: 4439613

Strand: Direct

Name: coaA

Synonym: Ping_3622

Alternate gene names: 119947224

Gene position: 4438645-4439613 (Clockwise)

Preceding gene: 119947223

Following gene: 119947225

Centisome position: 97.35

GC content: 39.32

Gene sequence:

>969_bases
GTGAAAATAAAAATTACAGCTGAAGAGGGGCAATATAACGCCCATGATGCCTATATGCACTTTGAAAGACAAAAGTGGGC
TGAATTGCGCGACAATGTTGAGTTAACCCTTTCCGAAGACGATCTAAGACAGTTACAAGGGATTAACGAATCACTTTCTA
TTCAAGAAGTGATTGATATTTACTTGCCACTGTCCCGTCTGCTTAATTTATATGTCAAAACACAGCAGCGTCGCCATACC
GTACGCGATAAATTTTTAAACTCAAAGAATGAAAACGTACCCTATATTATTGGTATTGCAGGCAGTGTTGCTGTGGGTAA
AAGTACCACAGCACGTATCCTGCAGGCTATTTTATCTCACTGGCCTGAGCACCCCAGAGTTGCCTTAGTGACAACCGATG
GTTTTTTACGGCCTAATCGAGAGCTGGTTGCACGTAATATAATGCACAAAAAGGGATTTCCAGAGAGTTTTGATACTAAG
GCATTAATTGATTTTGTTGCCGCAATAAAATCTGGTAAAGAGTTGATCTCTGCACCCATATATTCACATCTGACTTACGA
TATATTGCCTGATAAAAAGTTACACCTTGAAAAACCCGATATTGTTATATTAGAAGGTTTAAATGTATTACAAAGTGCAA
GCAATTATCCGGATCATCCGCAGCGCACTTTTGTCTCTGATTTTGTGGATTTTTCTATCTTTGTCGATGCAGAAACGCAG
CTCTTAAAAAAATGGTACGTACAACGCTTTCTAAAGTTTCGTAAAGGTGCATTTACTGATCCTAAAGCCTATTTCCATAG
TTATTCGCAAATGGAAGAAACTCAAGCGATTGATATTTCTGAAAAAATATGGGATGAGATCAATGGGGTTAATTTGGAAG
AAAATATTCGTCCAACCCGTGATAGAGCAAACCTGATCCTGACTAAGGCTACCGATCATCAGGTGGACAGCGTTCACCTG
CGGAAATAA

Upstream 100 bases:

>100_bases
AATCTCTTTGAACTGTTAATAAAACCCGCCGAGCAATATCACATCAGTACAGATAATCCAGAAGGTAACGCCAAATCAAT
TTACGTAGAGCAAGAATCTG

Downstream 100 bases:

>100_bases
GACATTCTAAAAATTAAAAAGTCGATTCAAAAGACTTCACTTTAAAAATAAGGGATAATTTGCGACTCACAAAAGTCGCC
ACCCATTTTGAACTAAAAAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKIKITAEEGQYNAHDAYMHFERQKWAELRDNVELTLSEDDLRQLQGINESLSIQEVIDIYLPLSRLLNLYVKTQQRRHT
VRDKFLNSKNENVPYIIGIAGSVAVGKSTTARILQAILSHWPEHPRVALVTTDGFLRPNRELVARNIMHKKGFPESFDTK
ALIDFVAAIKSGKELISAPIYSHLTYDILPDKKLHLEKPDIVILEGLNVLQSASNYPDHPQRTFVSDFVDFSIFVDAETQ
LLKKWYVQRFLKFRKGAFTDPKAYFHSYSQMEETQAIDISEKIWDEINGVNLEENIRPTRDRANLILTKATDHQVDSVHL
RK

Sequences:

>Translated_322_residues
MKIKITAEEGQYNAHDAYMHFERQKWAELRDNVELTLSEDDLRQLQGINESLSIQEVIDIYLPLSRLLNLYVKTQQRRHT
VRDKFLNSKNENVPYIIGIAGSVAVGKSTTARILQAILSHWPEHPRVALVTTDGFLRPNRELVARNIMHKKGFPESFDTK
ALIDFVAAIKSGKELISAPIYSHLTYDILPDKKLHLEKPDIVILEGLNVLQSASNYPDHPQRTFVSDFVDFSIFVDAETQ
LLKKWYVQRFLKFRKGAFTDPKAYFHSYSQMEETQAIDISEKIWDEINGVNLEENIRPTRDRANLILTKATDHQVDSVHL
RK
>Mature_322_residues
MKIKITAEEGQYNAHDAYMHFERQKWAELRDNVELTLSEDDLRQLQGINESLSIQEVIDIYLPLSRLLNLYVKTQQRRHT
VRDKFLNSKNENVPYIIGIAGSVAVGKSTTARILQAILSHWPEHPRVALVTTDGFLRPNRELVARNIMHKKGFPESFDTK
ALIDFVAAIKSGKELISAPIYSHLTYDILPDKKLHLEKPDIVILEGLNVLQSASNYPDHPQRTFVSDFVDFSIFVDAETQ
LLKKWYVQRFLKFRKGAFTDPKAYFHSYSQMEETQAIDISEKIWDEINGVNLEENIRPTRDRANLILTKATDHQVDSVHL
RK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=305, Percent_Identity=58.6885245901639, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_PSYIN (A1T0P0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944904.1
- ProteinModelPortal:   A1T0P0
- SMR:   A1T0P0
- STRING:   A1T0P0
- GeneID:   4625136
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3622
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- PhylomeDB:   A1T0P0
- ProtClustDB:   PRK05439
- BioCyc:   PING357804:PING_3622-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 37213; Mature: 37213

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKITAEEGQYNAHDAYMHFERQKWAELRDNVELTLSEDDLRQLQGINESLSIQEVIDI
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCCCCHHHHHHH
YLPLSRLLNLYVKTQQRRHTVRDKFLNSKNENVPYIIGIAGSVAVGKSTTARILQAILSH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHH
WPEHPRVALVTTDGFLRPNRELVARNIMHKKGFPESFDTKALIDFVAAIKSGKELISAPI
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
YSHLTYDILPDKKLHLEKPDIVILEGLNVLQSASNYPDHPQRTFVSDFVDFSIFVDAETQ
HHHCEEECCCCCCEECCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHCEEEEECCHHH
LLKKWYVQRFLKFRKGAFTDPKAYFHSYSQMEETQAIDISEKIWDEINGVNLEENIRPTR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCCCC
DRANLILTKATDHQVDSVHLRK
CCCCEEEEECCCCCCCCEECCC
>Mature Secondary Structure
MKIKITAEEGQYNAHDAYMHFERQKWAELRDNVELTLSEDDLRQLQGINESLSIQEVIDI
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCCCCCCHHHHHHH
YLPLSRLLNLYVKTQQRRHTVRDKFLNSKNENVPYIIGIAGSVAVGKSTTARILQAILSH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEECCCCHHHHHHHHHHHH
WPEHPRVALVTTDGFLRPNRELVARNIMHKKGFPESFDTKALIDFVAAIKSGKELISAPI
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
YSHLTYDILPDKKLHLEKPDIVILEGLNVLQSASNYPDHPQRTFVSDFVDFSIFVDAETQ
HHHCEEECCCCCCEECCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHCEEEEECCHHH
LLKKWYVQRFLKFRKGAFTDPKAYFHSYSQMEETQAIDISEKIWDEINGVNLEENIRPTR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCCCCC
DRANLILTKATDHQVDSVHLRK
CCCCEEEEECCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA