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The map label for this gene is argD [H]

Identifier: 119947218

GI number: 119947218

Start: 4431857

End: 4433068

Strand: Direct

Name: argD [H]

Synonym: Ping_3616

Alternate gene names: 119947218

Gene position: 4431857-4433068 (Clockwise)

Preceding gene: 119947217

Following gene: 119947219

Centisome position: 97.2

GC content: 41.34

Gene sequence:

>1212_bases
ATGTCAAACCCTGCTATCACTCGCGCGCTTTTTGATCAAATTATGGTGCCCAATTATGCCCCTTTAGCAATGATCCCTGT
TCGTGGTGAAGGCTCTCGTGTTTGGGATCAAGAAAATCGTGAATATATAGACCTAACCGGTGGAATCGCTGTAAATGCAC
TCGGCCATGCACATCCGGAATTAGTAACGGCATTAACGGAGCAAGCTAAAAAACTATGGCATGTCAGTAATTATTATACC
AATGAACCTGCTTTACAATTGGCACAGCAGATTATTGATAATACTTTTGCTGAAAAAGTTTTTTTTGCAAATTCTGGGGC
AGAAGCCAATGAAGCCGCATTAAAATTAGCGCGTCGTTTCGCTTTTGATAATTACGACAAAGAAAAAACTGAAATTATCG
CTTTCCATCACGGTTTTCATGGACGAACATTTTTTACAGTCAGTGCGGGTGGTAGTACCTCTTACTCCAATGGTTTTGGG
CCCAAACCAGGCGATATAACACACCTTGATTACAATGATTTAAGCGCATTAGAAAATGCAATGTCTGATAAAACCTGCGC
TGTTTTACTTGAGCCTCTGCAGGGTGAAGGCGGTGTTTTGCCGATCGATAAATCCTTTGCTCAGGGTGTCCGTAAACTCT
GTGATAAATATAATGCGCTAATGATTTTAGATGAAGTACAAACGGGTATGGGCCGCACCGGTTCATTATTTGCCTATATG
GCATTAGGTGTTATCCCAGATGTACTTACCTCTGCAAAATCCTTAGGAGCAGGTTTCCCTATTTCAGCAATGTTAACCTT
AGATAAATTTGCCAGCTGCCTGACGGTAGGAACACACGGCACAACATTTGGTGGCAATCCGCTTGCTTGTGCCGTTGCCA
GCAAAGCCTTTGAATTAATTAATAACGAGACCCTCTTAAACGGGGTAAAAGAAAAAGAACATTTAATACGTCATGCTCTG
GAGAAAATAAACCAACAATATGATGTTTTTAAAGAGGTTCGTGGGGCAGGTTTATTACTGGGAGCAGTTTTAAATGACCA
GTACCAGGATCGAGCAAAAGATTTACTGCTGGCAAGTGCAGATCAAGGTTTATTAGTACTGGCTGCAGGTGCAAATGTGA
TCCGTTTCGCACCCGCTCTCAACATCAGTCATCAAGAAATAGATCAGGCCATGGATAAATTTAAACAAGCAGTAAAAGTA
CTAACTAAATAA

Upstream 100 bases:

>100_bases
ATTTTATTGACCAATCACTTGGTTTCAAAAAATAAGTGCGTATATTAGCACCCATTATTTTAAGCCCTCATCTGGTGTTT
TTATTTTAAAGGATTTTTTT

Downstream 100 bases:

>100_bases
TCTAGCATGCCTATGCCTGTTACTCAGATTAATCGTTAAAAATGGGCAAAGATATCGCTTAATAACTGTTTTATACAATT
CATTGCGAAGCTCATCTATT

Product: acetylornithine and succinylornithine aminotransferases

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSNPAITRALFDQIMVPNYAPLAMIPVRGEGSRVWDQENREYIDLTGGIAVNALGHAHPELVTALTEQAKKLWHVSNYYT
NEPALQLAQQIIDNTFAEKVFFANSGAEANEAALKLARRFAFDNYDKEKTEIIAFHHGFHGRTFFTVSAGGSTSYSNGFG
PKPGDITHLDYNDLSALENAMSDKTCAVLLEPLQGEGGVLPIDKSFAQGVRKLCDKYNALMILDEVQTGMGRTGSLFAYM
ALGVIPDVLTSAKSLGAGFPISAMLTLDKFASCLTVGTHGTTFGGNPLACAVASKAFELINNETLLNGVKEKEHLIRHAL
EKINQQYDVFKEVRGAGLLLGAVLNDQYQDRAKDLLLASADQGLLVLAAGANVIRFAPALNISHQEIDQAMDKFKQAVKV
LTK

Sequences:

>Translated_403_residues
MSNPAITRALFDQIMVPNYAPLAMIPVRGEGSRVWDQENREYIDLTGGIAVNALGHAHPELVTALTEQAKKLWHVSNYYT
NEPALQLAQQIIDNTFAEKVFFANSGAEANEAALKLARRFAFDNYDKEKTEIIAFHHGFHGRTFFTVSAGGSTSYSNGFG
PKPGDITHLDYNDLSALENAMSDKTCAVLLEPLQGEGGVLPIDKSFAQGVRKLCDKYNALMILDEVQTGMGRTGSLFAYM
ALGVIPDVLTSAKSLGAGFPISAMLTLDKFASCLTVGTHGTTFGGNPLACAVASKAFELINNETLLNGVKEKEHLIRHAL
EKINQQYDVFKEVRGAGLLLGAVLNDQYQDRAKDLLLASADQGLLVLAAGANVIRFAPALNISHQEIDQAMDKFKQAVKV
LTK
>Mature_402_residues
SNPAITRALFDQIMVPNYAPLAMIPVRGEGSRVWDQENREYIDLTGGIAVNALGHAHPELVTALTEQAKKLWHVSNYYTN
EPALQLAQQIIDNTFAEKVFFANSGAEANEAALKLARRFAFDNYDKEKTEIIAFHHGFHGRTFFTVSAGGSTSYSNGFGP
KPGDITHLDYNDLSALENAMSDKTCAVLLEPLQGEGGVLPIDKSFAQGVRKLCDKYNALMILDEVQTGMGRTGSLFAYMA
LGVIPDVLTSAKSLGAGFPISAMLTLDKFASCLTVGTHGTTFGGNPLACAVASKAFELINNETLLNGVKEKEHLIRHALE
KINQQYDVFKEVRGAGLLLGAVLNDQYQDRAKDLLLASADQGLLVLAAGANVIRFAPALNISHQEIDQAMDKFKQAVKVL
TK

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=36.4341085271318, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.4548494983278, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=24.455205811138, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=24.6113989637306, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226442705, Length=413, Percent_Identity=23.728813559322, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI24119277, Length=406, Percent_Identity=24.8768472906404, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1788044, Length=399, Percent_Identity=58.8972431077694, Blast_Score=502, Evalue=1e-143,
Organism=Escherichia coli, GI1789759, Length=394, Percent_Identity=57.6142131979695, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.4170854271357, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787560, Length=398, Percent_Identity=33.9195979899498, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=32.9923273657289, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1786991, Length=327, Percent_Identity=30.8868501529052, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786349, Length=299, Percent_Identity=29.7658862876254, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=379, Percent_Identity=36.9393139841689, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32564660, Length=448, Percent_Identity=30.1339285714286, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=37.546468401487, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=424, Percent_Identity=27.5943396226415, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=33.75, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=441, Percent_Identity=23.3560090702948, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=37.8787878787879, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=35.0617283950617, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=340, Percent_Identity=32.0588235294118, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=24.7165532879819, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=37.0466321243523, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI161085790, Length=425, Percent_Identity=28, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI28574759, Length=424, Percent_Identity=28.3018867924528, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI281366494, Length=298, Percent_Identity=23.8255033557047, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24667139, Length=298, Percent_Identity=23.8255033557047, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24667143, Length=298, Percent_Identity=23.8255033557047, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43722; Mature: 43591

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPAITRALFDQIMVPNYAPLAMIPVRGEGSRVWDQENREYIDLTGGIAVNALGHAHPE
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCEEEECCCCCCHH
LVTALTEQAKKLWHVSNYYTNEPALQLAQQIIDNTFAEKVFFANSGAEANEAALKLARRF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHH
AFDNYDKEKTEIIAFHHGFHGRTFFTVSAGGSTSYSNGFGPKPGDITHLDYNDLSALENA
HCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHH
MSDKTCAVLLEPLQGEGGVLPIDKSFAQGVRKLCDKYNALMILDEVQTGMGRTGSLFAYM
HCCCEEEEHEECCCCCCCEECCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCHHHHHH
ALGVIPDVLTSAKSLGAGFPISAMLTLDKFASCLTVGTHGTTFGGNPLACAVASKAFELI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHH
NNETLLNGVKEKEHLIRHALEKINQQYDVFKEVRGAGLLLGAVLNDQYQDRAKDLLLASA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHHCCC
DQGLLVLAAGANVIRFAPALNISHQEIDQAMDKFKQAVKVLTK
CCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNPAITRALFDQIMVPNYAPLAMIPVRGEGSRVWDQENREYIDLTGGIAVNALGHAHPE
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCEEEECCCCCCHH
LVTALTEQAKKLWHVSNYYTNEPALQLAQQIIDNTFAEKVFFANSGAEANEAALKLARRF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHH
AFDNYDKEKTEIIAFHHGFHGRTFFTVSAGGSTSYSNGFGPKPGDITHLDYNDLSALENA
HCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHH
MSDKTCAVLLEPLQGEGGVLPIDKSFAQGVRKLCDKYNALMILDEVQTGMGRTGSLFAYM
HCCCEEEEHEECCCCCCCEECCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCHHHHHH
ALGVIPDVLTSAKSLGAGFPISAMLTLDKFASCLTVGTHGTTFGGNPLACAVASKAFELI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHH
NNETLLNGVKEKEHLIRHALEKINQQYDVFKEVRGAGLLLGAVLNDQYQDRAKDLLLASA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHHHHHCCC
DQGLLVLAAGANVIRFAPALNISHQEIDQAMDKFKQAVKVLTK
CCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]