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The map label for this gene is tmcA [H]

Identifier: 119947128

GI number: 119947128

Start: 4343517

End: 4345571

Strand: Direct

Name: tmcA [H]

Synonym: Ping_3526

Alternate gene names: 119947128

Gene position: 4343517-4345571 (Clockwise)

Preceding gene: 119947099

Following gene: 119947129

Centisome position: 95.26

GC content: 42.19

Gene sequence:

>2055_bases
GTGCCGGCACTTTTATCTTTGCTTGACCATCTTAAAAATCATGCGACAATTCAAAATCATCGCCAATTATTGCGTCTGCA
GGGCGACTTGAATTGGTGCTTTACCCTAACCCAAAAAATGATTGCTGAGCTGCAACTCCCCTATTTTTGGTGCGGCCCCA
GCCCGATTACCAATAACTCTATTTCATACAAAGAAATTTTAGGGCAAGAAACATCATTACTTGTTATTAATGCTCACCCG
GCTTTTGACGGCAATCAATTTGCTGCCGCTGAAGGTACCTTACGAGGAGGTGGATTATTAATTCTCTTAACACCGACAGA
TATTTCCTGTGATGATCTGTTTTACCAATATATAAGCGCACAATTACAACATTTTAACTTTCTCACCCTGAAGCAGGGTC
TTCCCTTACCCAACTTTACTCTCCCCCCTGCTAACAACTGCCCTGTTATCAATAAACAACCCGCGCTTAACCTCAGCGGA
CAACATAATGCAATTCAGGAAATCATTAAAACAGTGACGGGTCACCGCCGGAGACCACTGGTGTTAACAGCTGATAGAGG
AAGGGGGAAATCAGCCGCTCTGGGGATCGCTGCCGCGCAACTATTAAGTGAATCCAGAGTTAAAAAAATTCTGGTCTGCG
CGCCAAATAAGCAAGCGACCGCCACGCTGTTCAGACATGCAAACTTAATCTTAAAACCAGCGCATGGACAAAGTGGCACC
ACAACAATAGACCAAGGCACTATTGAGTTTATTGCAGCAGATACCCTGCTTGATGAATATCCTCAATGTGATCTGTTAAT
TATTGATGAGGCGGCCGCAATACCCGTGCCCACATTAGAATCTTTAGTGATTCATTACTCGCGACTTGTTTTTGCCACTA
CGCTCCATGGTTATGAAGGCTCTGGAAGAGGATTTGCACTGCGTTTTCAAAAACGCTTAACGGAATTGGCTCCTCAATGG
CGAAAGCTCCATCTGGACCAACCTATTCGCTGGGCAAAAAATGATCCTCTTGAAGCTTTTACGCTGAGCAGTATTTGCTT
AACGGAAGCCGTTGCACAACAGCCTGTTTATAAAGCACAACAGGCGCTTAGCTTTGAAAAACTGACTCCGGCAGAGTTAT
TAGCCGATAAAACATTATTACAAGCACTTTTTTCTTTATTGGTCTTGGCACACTATCAGACCAAACCATCGGATCTTGAA
AAATTACTTAATGACAGTTCAGTACATATTTTTATTGCCAGGCAACAAGGGCAAATACTCGGGGTTGCACTTATAAAGGA
AGAAGGTAATTTTGACCACAATCTCTGCGAGCAAATATGGCGGGGATCGCGCCGCGTGCCTGGACACCTAATAGCTCAAT
CTTTAACTTTTCATAGCCGATTTCAGCTAGCGGCATCGAATTCTTATGCCAGAATACAACGGATAGCGATTCACCCTGAC
TGTCAGAATCGCGGTATAGGCAAACAATTTATAAACCACTTAATTGGTTGGGCGAAAAAACAGGCCTTTGATCATCTGTG
TGTCAGTTATGGCGTGACAGCTGATTTATTATCTTTCTGGCAAAAGCGCCACTTTGTCCCCTTACGTATCGGTCTTAGTC
AGGATGCAAGCAGCGGCACACATTCTCTGATAATGAATTTACCTCTTTCTAAAAGAGCGCATCTCTTACATCAATTAATT
GTTCAACAATTCAGGCAACAACTGCCCACCCAATTAAGTCGACACCTGCAGCATTTAGATACGGAGGTGGTTTTAAAATT
ATTATTAAACAGCAGTAAAGTGCAATCTGACCAGCCAAGCTTACTCAGTTATACGCAGGGCCATTTACCCTATGAGTTTA
TTGAACACGATCTGATAGATTTAATGTTAAACTGCGATTTAACCGGTTTAAGCAAAGCACAACAATGTCTGGCTATCCAG
AAAATCTTACAAAATAATAGTTGGGCAGAGATTTGCAGAAAAAATAATTTAACAGGCAAAAAACAAGCCCAATATATTCT
AAAAGAAACCATCAAACAGTTAACCACTAACGTTACCAAAAGAGGAAATCAATGA

Upstream 100 bases:

>100_bases
ATTAACAACAGAGCCACTCTTAGCTTGACAGTGACAGTCCCTGTCTGGGTATATACTAACGATCAAATACACACTGTCAC
ACACACATGGGGAGTTTTTC

Downstream 100 bases:

>100_bases
GATTAGATAAATACATTTGTGAGTCTACCACTATGACCAGAAGCCAGGCTAAAAAGGTCATTATCCAGGGACGTATAACA
AGCGACGGCACTGTCATGCG

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MPALLSLLDHLKNHATIQNHRQLLRLQGDLNWCFTLTQKMIAELQLPYFWCGPSPITNNSISYKEILGQETSLLVINAHP
AFDGNQFAAAEGTLRGGGLLILLTPTDISCDDLFYQYISAQLQHFNFLTLKQGLPLPNFTLPPANNCPVINKQPALNLSG
QHNAIQEIIKTVTGHRRRPLVLTADRGRGKSAALGIAAAQLLSESRVKKILVCAPNKQATATLFRHANLILKPAHGQSGT
TTIDQGTIEFIAADTLLDEYPQCDLLIIDEAAAIPVPTLESLVIHYSRLVFATTLHGYEGSGRGFALRFQKRLTELAPQW
RKLHLDQPIRWAKNDPLEAFTLSSICLTEAVAQQPVYKAQQALSFEKLTPAELLADKTLLQALFSLLVLAHYQTKPSDLE
KLLNDSSVHIFIARQQGQILGVALIKEEGNFDHNLCEQIWRGSRRVPGHLIAQSLTFHSRFQLAASNSYARIQRIAIHPD
CQNRGIGKQFINHLIGWAKKQAFDHLCVSYGVTADLLSFWQKRHFVPLRIGLSQDASSGTHSLIMNLPLSKRAHLLHQLI
VQQFRQQLPTQLSRHLQHLDTEVVLKLLLNSSKVQSDQPSLLSYTQGHLPYEFIEHDLIDLMLNCDLTGLSKAQQCLAIQ
KILQNNSWAEICRKNNLTGKKQAQYILKETIKQLTTNVTKRGNQ

Sequences:

>Translated_684_residues
MPALLSLLDHLKNHATIQNHRQLLRLQGDLNWCFTLTQKMIAELQLPYFWCGPSPITNNSISYKEILGQETSLLVINAHP
AFDGNQFAAAEGTLRGGGLLILLTPTDISCDDLFYQYISAQLQHFNFLTLKQGLPLPNFTLPPANNCPVINKQPALNLSG
QHNAIQEIIKTVTGHRRRPLVLTADRGRGKSAALGIAAAQLLSESRVKKILVCAPNKQATATLFRHANLILKPAHGQSGT
TTIDQGTIEFIAADTLLDEYPQCDLLIIDEAAAIPVPTLESLVIHYSRLVFATTLHGYEGSGRGFALRFQKRLTELAPQW
RKLHLDQPIRWAKNDPLEAFTLSSICLTEAVAQQPVYKAQQALSFEKLTPAELLADKTLLQALFSLLVLAHYQTKPSDLE
KLLNDSSVHIFIARQQGQILGVALIKEEGNFDHNLCEQIWRGSRRVPGHLIAQSLTFHSRFQLAASNSYARIQRIAIHPD
CQNRGIGKQFINHLIGWAKKQAFDHLCVSYGVTADLLSFWQKRHFVPLRIGLSQDASSGTHSLIMNLPLSKRAHLLHQLI
VQQFRQQLPTQLSRHLQHLDTEVVLKLLLNSSKVQSDQPSLLSYTQGHLPYEFIEHDLIDLMLNCDLTGLSKAQQCLAIQ
KILQNNSWAEICRKNNLTGKKQAQYILKETIKQLTTNVTKRGNQ
>Mature_683_residues
PALLSLLDHLKNHATIQNHRQLLRLQGDLNWCFTLTQKMIAELQLPYFWCGPSPITNNSISYKEILGQETSLLVINAHPA
FDGNQFAAAEGTLRGGGLLILLTPTDISCDDLFYQYISAQLQHFNFLTLKQGLPLPNFTLPPANNCPVINKQPALNLSGQ
HNAIQEIIKTVTGHRRRPLVLTADRGRGKSAALGIAAAQLLSESRVKKILVCAPNKQATATLFRHANLILKPAHGQSGTT
TIDQGTIEFIAADTLLDEYPQCDLLIIDEAAAIPVPTLESLVIHYSRLVFATTLHGYEGSGRGFALRFQKRLTELAPQWR
KLHLDQPIRWAKNDPLEAFTLSSICLTEAVAQQPVYKAQQALSFEKLTPAELLADKTLLQALFSLLVLAHYQTKPSDLEK
LLNDSSVHIFIARQQGQILGVALIKEEGNFDHNLCEQIWRGSRRVPGHLIAQSLTFHSRFQLAASNSYARIQRIAIHPDC
QNRGIGKQFINHLIGWAKKQAFDHLCVSYGVTADLLSFWQKRHFVPLRIGLSQDASSGTHSLIMNLPLSKRAHLLHQLIV
QQFRQQLPTQLSRHLQHLDTEVVLKLLLNSSKVQSDQPSLLSYTQGHLPYEFIEHDLIDLMLNCDLTGLSKAQQCLAIQK
ILQNNSWAEICRKNNLTGKKQAQYILKETIKQLTTNVTKRGNQ

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI221316741, Length=575, Percent_Identity=25.5652173913043, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI221316723, Length=572, Percent_Identity=25.5244755244755, Blast_Score=104, Evalue=3e-22,
Organism=Escherichia coli, GI1788818, Length=685, Percent_Identity=30.6569343065693, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17507621, Length=479, Percent_Identity=23.7995824634656, Blast_Score=115, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324197, Length=571, Percent_Identity=25.569176882662, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24640662, Length=701, Percent_Identity=26.1055634807418, Blast_Score=148, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 76583; Mature: 76452

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALLSLLDHLKNHATIQNHRQLLRLQGDLNWCFTLTQKMIAELQLPYFWCGPSPITNNS
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
ISYKEILGQETSLLVINAHPAFDGNQFAAAEGTLRGGGLLILLTPTDISCDDLFYQYISA
CCHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QLQHFNFLTLKQGLPLPNFTLPPANNCPVINKQPALNLSGQHNAIQEIIKTVTGHRRRPL
HHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
VLTADRGRGKSAALGIAAAQLLSESRVKKILVCAPNKQATATLFRHANLILKPAHGQSGT
EEEECCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCEEEECCCCCCCC
TTIDQGTIEFIAADTLLDEYPQCDLLIIDEAAAIPVPTLESLVIHYSRLVFATTLHGYEG
EEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SGRGFALRFQKRLTELAPQWRKLHLDQPIRWAKNDPLEAFTLSSICLTEAVAQQPVYKAQ
CCCCEEHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHH
QALSFEKLTPAELLADKTLLQALFSLLVLAHYQTKPSDLEKLLNDSSVHIFIARQQGQIL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEE
GVALIKEEGNFDHNLCEQIWRGSRRVPGHLIAQSLTFHSRFQLAASNSYARIQRIAIHPD
EEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCHHHEEEEEECCC
CQNRGIGKQFINHLIGWAKKQAFDHLCVSYGVTADLLSFWQKRHFVPLRIGLSQDASSGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCC
HSLIMNLPLSKRAHLLHQLIVQQFRQQLPTQLSRHLQHLDTEVVLKLLLNSSKVQSDQPS
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
LLSYTQGHLPYEFIEHDLIDLMLNCDLTGLSKAQQCLAIQKILQNNSWAEICRKNNLTGK
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCH
KQAQYILKETIKQLTTNVTKRGNQ
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PALLSLLDHLKNHATIQNHRQLLRLQGDLNWCFTLTQKMIAELQLPYFWCGPSPITNNS
CHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCC
ISYKEILGQETSLLVINAHPAFDGNQFAAAEGTLRGGGLLILLTPTDISCDDLFYQYISA
CCHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
QLQHFNFLTLKQGLPLPNFTLPPANNCPVINKQPALNLSGQHNAIQEIIKTVTGHRRRPL
HHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCE
VLTADRGRGKSAALGIAAAQLLSESRVKKILVCAPNKQATATLFRHANLILKPAHGQSGT
EEEECCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHCCEEEECCCCCCCC
TTIDQGTIEFIAADTLLDEYPQCDLLIIDEAAAIPVPTLESLVIHYSRLVFATTLHGYEG
EEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SGRGFALRFQKRLTELAPQWRKLHLDQPIRWAKNDPLEAFTLSSICLTEAVAQQPVYKAQ
CCCCEEHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHH
QALSFEKLTPAELLADKTLLQALFSLLVLAHYQTKPSDLEKLLNDSSVHIFIARQQGQIL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEECCCCEE
GVALIKEEGNFDHNLCEQIWRGSRRVPGHLIAQSLTFHSRFQLAASNSYARIQRIAIHPD
EEEEEECCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCHHHEEEEEECCC
CQNRGIGKQFINHLIGWAKKQAFDHLCVSYGVTADLLSFWQKRHFVPLRIGLSQDASSGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCC
HSLIMNLPLSKRAHLLHQLIVQQFRQQLPTQLSRHLQHLDTEVVLKLLLNSSKVQSDQPS
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
LLSYTQGHLPYEFIEHDLIDLMLNCDLTGLSKAQQCLAIQKILQNNSWAEICRKNNLTGK
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCH
KQAQYILKETIKQLTTNVTKRGNQ
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA