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The map label for this gene is asd [H]

Identifier: 119946812

GI number: 119946812

Start: 3961490

End: 3962602

Strand: Direct

Name: asd [H]

Synonym: Ping_3206

Alternate gene names: 119946812

Gene position: 3961490-3962602 (Clockwise)

Preceding gene: 119946811

Following gene: 119946817

Centisome position: 86.88

GC content: 43.13

Gene sequence:

>1113_bases
ATGAAAAAAGTAGGCTTAGTTGGTTGGCGCGGTATGGTGGGCTCTGTGCTTATGCAAAGAATGCGCGATGAAAATGATTT
TGCAACAATTGAACCTGTATTTTTTACCACCTCGCAAATTGGCCTTTTGGCACCTGAAATTGGTAAACCAAGTGATACAT
TAAAAGATGCATTTGCCATTGACGAACTGGCTAAGATGGACATCGTGGTCACTTGCCAAGGTGGTGATTATACTAATGAA
GTCTACCCAAAACTGCGCGCTGCGGGCTGGAAGGGTTACTGGATTGATGCCGCGTCTTCATTACGTATGCAGGATGACAG
TATTATCGCATTAGATCCTGTCAACAAAGATGTTATACAACAAGGCATTAAAGACGGAGTGAAAACTTTCGTTGGCGGTA
ACTGTACTGTTTCATTATTATTAATGGCATTGGGCGGTTTATTCGAAGAAGAACTCATCGAGTGGGTAACCCCGCATACT
TATCAGGCAGCTTCGGGCGCCGGTGCACGAAATATGCGCGAACTAATTAGTCAGATGGGCTCTATTAGTGCGTCTGTTGC
CGATAAATTAGCCGATCCTGCCTCTGCGATTTTAGAAATAGATCAGCAGGTAGCTGAACATATTCGTAGTGATGCGCTGC
CAAAAGAGCAGTTTGGAGCCCCCTTGGCAGGTAGTTTAATTCCCTGGATTGATGTTCCTATGCCATCTGGTCAAAGTAAA
GAAGAGTGGAAAGCACAGGTTGAAGCAAATAAAATTTTAGGAACAAGTGACAAGCAGGTGCCAATTGATGGTTTATGTGT
CCGTATTGGTGCAATGCGCTGCCATAGTCAGGCAATCACTATGAAACTAAAAAAAGATATTTCAGTTGCTGAAATTGAAC
GCATTTTAGGTGCCCATAATGAGTGGGTTAAAGTGATTCCAAATGAACGTGATATCACAATAGAAGAACTTTCTCCTGCT
AAAGTAACGGGTACTTTAACGATTCCTGTTGGCCGAATTCGAAAATTAGCAATGGGACCAGAATACGTTACTGCATTTAC
GGTTGGTGACCAATTATTATGGGGCGCGGCTGAACCACTTCGTCGTATGCTGAACATTCTACAAGCGTCATAA

Upstream 100 bases:

>100_bases
AACACTAGCCATAGCAAAGCAGAAAATGGTAGATTTAAGGCTCAGGTTAATCATTAACCGCAACATTTTTTATTTGTTTA
ACAGAAAGGATTAATAGATC

Downstream 100 bases:

>100_bases
ATTTTACACGGCAAATAAAAAAGGCTTCAAATAAGAAGCCTTTTTTAATGCATAAAATCAACCAACCATAACAGCGATTA
GAAAAGAATAATCACTCGTC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKKVGLVGWRGMVGSVLMQRMRDENDFATIEPVFFTTSQIGLLAPEIGKPSDTLKDAFAIDELAKMDIVVTCQGGDYTNE
VYPKLRAAGWKGYWIDAASSLRMQDDSIIALDPVNKDVIQQGIKDGVKTFVGGNCTVSLLLMALGGLFEEELIEWVTPHT
YQAASGAGARNMRELISQMGSISASVADKLADPASAILEIDQQVAEHIRSDALPKEQFGAPLAGSLIPWIDVPMPSGQSK
EEWKAQVEANKILGTSDKQVPIDGLCVRIGAMRCHSQAITMKLKKDISVAEIERILGAHNEWVKVIPNERDITIEELSPA
KVTGTLTIPVGRIRKLAMGPEYVTAFTVGDQLLWGAAEPLRRMLNILQAS

Sequences:

>Translated_370_residues
MKKVGLVGWRGMVGSVLMQRMRDENDFATIEPVFFTTSQIGLLAPEIGKPSDTLKDAFAIDELAKMDIVVTCQGGDYTNE
VYPKLRAAGWKGYWIDAASSLRMQDDSIIALDPVNKDVIQQGIKDGVKTFVGGNCTVSLLLMALGGLFEEELIEWVTPHT
YQAASGAGARNMRELISQMGSISASVADKLADPASAILEIDQQVAEHIRSDALPKEQFGAPLAGSLIPWIDVPMPSGQSK
EEWKAQVEANKILGTSDKQVPIDGLCVRIGAMRCHSQAITMKLKKDISVAEIERILGAHNEWVKVIPNERDITIEELSPA
KVTGTLTIPVGRIRKLAMGPEYVTAFTVGDQLLWGAAEPLRRMLNILQAS
>Mature_370_residues
MKKVGLVGWRGMVGSVLMQRMRDENDFATIEPVFFTTSQIGLLAPEIGKPSDTLKDAFAIDELAKMDIVVTCQGGDYTNE
VYPKLRAAGWKGYWIDAASSLRMQDDSIIALDPVNKDVIQQGIKDGVKTFVGGNCTVSLLLMALGGLFEEELIEWVTPHT
YQAASGAGARNMRELISQMGSISASVADKLADPASAILEIDQQVAEHIRSDALPKEQFGAPLAGSLIPWIDVPMPSGQSK
EEWKAQVEANKILGTSDKQVPIDGLCVRIGAMRCHSQAITMKLKKDISVAEIERILGAHNEWVKVIPNERDITIEELSPA
KVTGTLTIPVGRIRKLAMGPEYVTAFTVGDQLLWGAAEPLRRMLNILQAS

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=66.4850136239782, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 40299; Mature: 40299

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVGLVGWRGMVGSVLMQRMRDENDFATIEPVFFTTSQIGLLAPEIGKPSDTLKDAFAI
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEECEEEEECCCCCEECCCCCCCHHHHHHHHHH
DELAKMDIVVTCQGGDYTNEVYPKLRAAGWKGYWIDAASSLRMQDDSIIALDPVNKDVIQ
HHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCEECCCCEEEECCCCHHHHH
QGIKDGVKTFVGGNCTVSLLLMALGGLFEEELIEWVTPHTYQAASGAGARNMRELISQMG
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SISASVADKLADPASAILEIDQQVAEHIRSDALPKEQFGAPLAGSLIPWIDVPMPSGQSK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEECCCCCCCCH
EEWKAQVEANKILGTSDKQVPIDGLCVRIGAMRCHSQAITMKLKKDISVAEIERILGAHN
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
EWVKVIPNERDITIEELSPAKVTGTLTIPVGRIRKLAMGPEYVTAFTVGDQLLWGAAEPL
CEEEECCCCCCEEHCCCCCCEEEEEEEECHHHHHHHHCCCCCEEEEEECCHHHHCCHHHH
RRMLNILQAS
HHHHHHHHCC
>Mature Secondary Structure
MKKVGLVGWRGMVGSVLMQRMRDENDFATIEPVFFTTSQIGLLAPEIGKPSDTLKDAFAI
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEECEEEEECCCCCEECCCCCCCHHHHHHHHHH
DELAKMDIVVTCQGGDYTNEVYPKLRAAGWKGYWIDAASSLRMQDDSIIALDPVNKDVIQ
HHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCEEEECCCCCEECCCCEEEECCCCHHHHH
QGIKDGVKTFVGGNCTVSLLLMALGGLFEEELIEWVTPHTYQAASGAGARNMRELISQMG
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
SISASVADKLADPASAILEIDQQVAEHIRSDALPKEQFGAPLAGSLIPWIDVPMPSGQSK
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEECCCCCCCCH
EEWKAQVEANKILGTSDKQVPIDGLCVRIGAMRCHSQAITMKLKKDISVAEIERILGAHN
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
EWVKVIPNERDITIEELSPAKVTGTLTIPVGRIRKLAMGPEYVTAFTVGDQLLWGAAEPL
CEEEECCCCCCEEHCCCCCCEEEEEEEECHHHHHHHHCCCCCEEEEEECCHHHHCCHHHH
RRMLNILQAS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]