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The map label for this gene is hyi [H]

Identifier: 119946671

GI number: 119946671

Start: 3750035

End: 3750805

Strand: Reverse

Name: hyi [H]

Synonym: Ping_3052

Alternate gene names: 119946671

Gene position: 3750805-3750035 (Counterclockwise)

Preceding gene: 119946672

Following gene: 119946660

Centisome position: 82.26

GC content: 41.63

Gene sequence:

>771_bases
ATGCGTAAAAATTTAGTTCCTTCTGTTTGTATTGATGCGGTTTTTAGTGGTCAATCTTTCGATCAGGCTTGTGCACAGGT
TAAAGATGCTAATATCAGTCATATCGAATTTTGGGGCTGGTGGGACAAAGATCTTGATAGCTTACAAGCAGCGCAGCATA
AACAGGGTTTAACAATAGCGGCTTGTTGTACCAAATTTATCAGTTTAGTTGAGCCTGCACTGCGTGATAATTATTTACAG
GGACTGCAGGAATCGATTCAAGCGGCGCAGAAACTGGGCATTAAAATATTGATATCGCAGGTTGGTGATTTTATTGAATC
TAGATCGCGAGCGGAGCAGCAACAATCAATTATAAATGGCTTAAAAGCCGCCGCGCCTTTATTAGAAGCGGCAGATATAA
CCCTAGTAATAGAGCCGCTTAATGAACGGGTTGATCATGCCGGTTATTTCCTGGTTCGCAGTGATCAGGCTTTTGATATT
GTTAAACAAGTCGCAAGCCCAAAGGTAAAAGTATTATTTGATATTTATCATCAGCAGATAAGTGAAGGTAATGTTATCCG
TAATATTGTCGATAATATTGATTATATCGGCCACTTCCATGCGGCAGGTAATCCGGGTAGAAATGAACTACAACGTGGCG
AAATTAATTATCCACAGGTATTTTCCGCCATTCAAAAAACAAACTTTATCGGGCATGTCGGCCTTGAATATTGGCCAACG
AACGATCAGCCGGTTGCGGCGCTGCGCGACGTTGCCACCTGGTTAATTTAA

Upstream 100 bases:

>100_bases
AACTAACCTATTAACACTGCGTTATTCGTTTTATACCCAAGTCACCTGAATCTTCAGGCAGCTTAGGTATAAAACCTTCT
TAAATTATTTGGGGTATTTT

Downstream 100 bases:

>100_bases
TCTGTACAGCCAAATCGGCGCAACCATATCGATATAAGGAGTGGGTCCAAAGGTTTTGAACTCACTGCTTTGATGATTTT
TTTTCTCTGGTTATTTTAAT

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRKNLVPSVCIDAVFSGQSFDQACAQVKDANISHIEFWGWWDKDLDSLQAAQHKQGLTIAACCTKFISLVEPALRDNYLQ
GLQESIQAAQKLGIKILISQVGDFIESRSRAEQQQSIINGLKAAAPLLEAADITLVIEPLNERVDHAGYFLVRSDQAFDI
VKQVASPKVKVLFDIYHQQISEGNVIRNIVDNIDYIGHFHAAGNPGRNELQRGEINYPQVFSAIQKTNFIGHVGLEYWPT
NDQPVAALRDVATWLI

Sequences:

>Translated_256_residues
MRKNLVPSVCIDAVFSGQSFDQACAQVKDANISHIEFWGWWDKDLDSLQAAQHKQGLTIAACCTKFISLVEPALRDNYLQ
GLQESIQAAQKLGIKILISQVGDFIESRSRAEQQQSIINGLKAAAPLLEAADITLVIEPLNERVDHAGYFLVRSDQAFDI
VKQVASPKVKVLFDIYHQQISEGNVIRNIVDNIDYIGHFHAAGNPGRNELQRGEINYPQVFSAIQKTNFIGHVGLEYWPT
NDQPVAALRDVATWLI
>Mature_256_residues
MRKNLVPSVCIDAVFSGQSFDQACAQVKDANISHIEFWGWWDKDLDSLQAAQHKQGLTIAACCTKFISLVEPALRDNYLQ
GLQESIQAAQKLGIKILISQVGDFIESRSRAEQQQSIINGLKAAAPLLEAADITLVIEPLNERVDHAGYFLVRSDQAFDI
VKQVASPKVKVLFDIYHQQISEGNVIRNIVDNIDYIGHFHAAGNPGRNELQRGEINYPQVFSAIQKTNFIGHVGLEYWPT
NDQPVAALRDVATWLI

Specific function: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) [H]

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=176, Percent_Identity=31.25, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI300068964, Length=168, Percent_Identity=30.3571428571429, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786718, Length=168, Percent_Identity=33.9285714285714, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789095, Length=130, Percent_Identity=31.5384615384615, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081874, Length=231, Percent_Identity=22.0779220779221, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17530883, Length=176, Percent_Identity=30.1136363636364, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017643
- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =5.3.1.22 [H]

Molecular weight: Translated: 28539; Mature: 28539

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNLVPSVCIDAVFSGQSFDQACAQVKDANISHIEFWGWWDKDLDSLQAAQHKQGLTIA
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHH
ACCTKFISLVEPALRDNYLQGLQESIQAAQKLGIKILISQVGDFIESRSRAEQQQSIING
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAAPLLEAADITLVIEPLNERVDHAGYFLVRSDQAFDIVKQVASPKVKVLFDIYHQQI
HHHHHHHHHHCCCEEEEECHHHHHHHCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHH
SEGNVIRNIVDNIDYIGHFHAAGNPGRNELQRGEINYPQVFSAIQKTNFIGHVGLEYWPT
CCCHHHHHHHHHHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCEECCCEEECC
NDQPVAALRDVATWLI
CCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRKNLVPSVCIDAVFSGQSFDQACAQVKDANISHIEFWGWWDKDLDSLQAAQHKQGLTIA
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHH
ACCTKFISLVEPALRDNYLQGLQESIQAAQKLGIKILISQVGDFIESRSRAEQQQSIING
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAAPLLEAADITLVIEPLNERVDHAGYFLVRSDQAFDIVKQVASPKVKVLFDIYHQQI
HHHHHHHHHHCCCEEEEECHHHHHHHCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHH
SEGNVIRNIVDNIDYIGHFHAAGNPGRNELQRGEINYPQVFSAIQKTNFIGHVGLEYWPT
CCCHHHHHHHHHHHHHEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCEECCCEEECC
NDQPVAALRDVATWLI
CCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8440684; 10561547; 9278503 [H]