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The map label for this gene is frr

Identifier: 119946594

GI number: 119946594

Start: 3666280

End: 3666837

Strand: Reverse

Name: frr

Synonym: Ping_2973

Alternate gene names: 119946594

Gene position: 3666837-3666280 (Counterclockwise)

Preceding gene: 119946595

Following gene: 119946593

Centisome position: 80.42

GC content: 40.14

Gene sequence:

>558_bases
ATGATCAATGAAGTTAAAAGTGATGCTCAATCCCGTATGGATAAAAGTGTTGAAGCATTTAGAAGCCAACTTTCAAAAAT
TCGCACGGGTCGTGCACACCCAAGTTTATTAGATGGTATTATGGTGCCGTATTACGGCAGTAATACACCGCTTCGTCAGG
TTGGTAATGTCTCTACTGAGGATGCCCGTACATTAACGGTCACGGTTTTTGATGCCTCGTTAATTAAGGCAGTGGAAAAA
GCGATAATGGGCTCAAGTTTAGGTTTAAACCCGATGTCTGCGGGTACTGTGATTCGTATCCCTTTGCCTCCGCTAACAGA
AGAGCGTCGTCGTGATTTAATTAAAATTGTGCGTGGTGAAGCTGAAAATAGTCGTATTGCTATCCGGAATATTCGTCGTG
ATGCAAATAACGATTTAAAATTACTGGAAAAAGATAAAGATATCAGTGAAGATGAACAACGTGTTGGCGAAGAGCTAGTG
CAAAAAACAACTAATGATCATATTAAACAGATTGAAGATCTGCTTGTCGTCAAAGAAGCTGAGCTACTTGAAGTTTAA

Upstream 100 bases:

>100_bases
GTGTTGTGTTAGGCGAAGATGAAGGTACAACTATTAAACATTGTGAGACAATAATAGAAAAAGAATAATCAATTTATAAC
CGAAAATTAGGGAAATTTTT

Downstream 100 bases:

>100_bases
CTATCTAGTGTTAGCGTATCCCTATTTTGGATATGCTAACTAATGTTCCGCTATTTTTCAATTCATCAAGGTTGATTGTG
ACCACATCAAATGAAAATTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEVKSDAQSRMDKSVEAFRSQLSKIRTGRAHPSLLDGIMVPYYGSNTPLRQVGNVSTEDARTLTVTVFDASLIKAVEK
AIMGSSLGLNPMSAGTVIRIPLPPLTEERRRDLIKIVRGEAENSRIAIRNIRRDANNDLKLLEKDKDISEDEQRVGEELV
QKTTNDHIKQIEDLLVVKEAELLEV

Sequences:

>Translated_185_residues
MINEVKSDAQSRMDKSVEAFRSQLSKIRTGRAHPSLLDGIMVPYYGSNTPLRQVGNVSTEDARTLTVTVFDASLIKAVEK
AIMGSSLGLNPMSAGTVIRIPLPPLTEERRRDLIKIVRGEAENSRIAIRNIRRDANNDLKLLEKDKDISEDEQRVGEELV
QKTTNDHIKQIEDLLVVKEAELLEV
>Mature_185_residues
MINEVKSDAQSRMDKSVEAFRSQLSKIRTGRAHPSLLDGIMVPYYGSNTPLRQVGNVSTEDARTLTVTVFDASLIKAVEK
AIMGSSLGLNPMSAGTVIRIPLPPLTEERRRDLIKIVRGEAENSRIAIRNIRRDANNDLKLLEKDKDISEDEQRVGEELV
QKTTNDHIKQIEDLLVVKEAELLEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=32, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=64.1304347826087, Blast_Score=243, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PSYIN (A1SYW0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944274.1
- ProteinModelPortal:   A1SYW0
- SMR:   A1SYW0
- STRING:   A1SYW0
- GeneID:   4624777
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2973
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   A1SYW0
- BioCyc:   PING357804:PING_2973-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20704; Mature: 20704

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEVKSDAQSRMDKSVEAFRSQLSKIRTGRAHPSLLDGIMVPYYGSNTPLRQVGNVSTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCEECCCCCCCCCHHHHCCCCCC
DARTLTVTVFDASLIKAVEKAIMGSSLGLNPMSAGTVIRIPLPPLTEERRRDLIKIVRGE
CCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENSRIAIRNIRRDANNDLKLLEKDKDISEDEQRVGEELVQKTTNDHIKQIEDLLVVKEA
CCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELLEV
HHHCC
>Mature Secondary Structure
MINEVKSDAQSRMDKSVEAFRSQLSKIRTGRAHPSLLDGIMVPYYGSNTPLRQVGNVSTE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCEECCCCCCCCCHHHHCCCCCC
DARTLTVTVFDASLIKAVEKAIMGSSLGLNPMSAGTVIRIPLPPLTEERRRDLIKIVRGE
CCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
AENSRIAIRNIRRDANNDLKLLEKDKDISEDEQRVGEELVQKTTNDHIKQIEDLLVVKEA
CCCCHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ELLEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA