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The map label for this gene is aprE [H]

Identifier: 119946468

GI number: 119946468

Start: 3494224

End: 3495438

Strand: Reverse

Name: aprE [H]

Synonym: Ping_2843

Alternate gene names: 119946468

Gene position: 3495438-3494224 (Counterclockwise)

Preceding gene: 119946469

Following gene: 119946467

Centisome position: 76.66

GC content: 47.49

Gene sequence:

>1215_bases
ATGTTATTTGATAGTTTTTTTGGAGATGATGACGCTGGCGGTAAAGAGAAGGCCGCGCGATTAGAAGGGTATTATCGGCG
CAATTATTCCGTGGTTTTATGGGTATTATTATTAGGTATGATAGGGTTTGGCTTCTGGTCAGCAAGCTTTCGTATCGATC
AAGTTGCGCGGGCGACAGGTGAGGTGATTGCCAGCAGCCGTGTGCAGATTATACAAGCGGTCGATGGAGGCGTCCTGTCG
ACCTTGAATGTTAAAGAGGGCGATCGTGTTGCTAAAGGCGAAGTATTGGCAACGTTAGATCAAACGCGTATTGGTGCGGC
GGTAAAAGAAGTCGATGTGCGCTTATCGGCTTTAAAAGCTAAGGCGACACGCTTACGTGCTGAAGTGACCGGATCTAAGC
GCTTAATTTTTCCGGAAGGGGTGCAGCGTTTTCCTGATTTAATGAAGGTTGAACGCGCTTTGTTTGAGCAGAAACAAACG
GGTTTATCGGAAGAGTTACGCACCCTTAAGGTAGCCGTTTCATTAGCAGGGGAAGAGGCTGAATTAATTAAGGAACTGTC
TGGCTCGGGTGATGTTAACCGCACAGAAGTTATCCGTTCTGCGCGGGCCTTAAATGATGCACAGGCGCAGCTTATTAACC
GTAAAAACAAGTACCTTGAAGAGGTCAGTTCGGAATTGGCAAAAGCGGAGGATGAAATAGCGCAGAATGTGCAGATTTTA
ACCCAGCGTCAGCAGCAGCTAGCCGACAGTGTTTTTATTGCCTCGCTGCCCGGCATTGTTAAGAATGTGCGTGTAACGAC
GTTGGGCGGCGTATTGCGCGGCGGGGATGAATTAATGCAGATTATTCCGGTTGATGATGAGCTGATTATTGAAGCTAAGG
TCAGCCCGGCTGATATTGGTCAAGTGCAAAAGGGGTTGCAGGCCACCATACGTTTTGATCCCTTTGATTATACCATTTAT
GGTGGTGTTATCGGCGAGGTTATCTATGTCAGTGGGGATACACTAAAAGAAGAGACCGGTCAGGGGGAAGAAATCTATTA
CCGGGTGCATGTCACAACTCAAACTTCGCCGGTCACCACAACGTCAGGTCGGGTATTAGAAATACTGCCCGGTATGACGG
CGCAGGTTGATATTAAAACCAGTGACAGAACTGTGCTTAATTATTTGTTAAAACCACTGCGCAAAACGCTTTCTGAATCC
TTTGGCGAGCGCTAG

Upstream 100 bases:

>100_bases
CCGAAAATAATGCAGCGCAACACCCCCGCCGCTACTAAGCCATCGGGACTGCGGACGCCTAAAAGCTTTAATCAGGACGT
AATAAAGAAGGAATCAAACA

Downstream 100 bases:

>100_bases
TTTTAAGGCTTTTTGGCGCAATGCTGTGACGCTGCCGTTTATCCCAGAGCTAATACAATATATCCTGCCGGTAAAGGGAT
CTTGGCTTTAGCCTGATCCC

Product: type I secretion membrane fusion protein, HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MLFDSFFGDDDAGGKEKAARLEGYYRRNYSVVLWVLLLGMIGFGFWSASFRIDQVARATGEVIASSRVQIIQAVDGGVLS
TLNVKEGDRVAKGEVLATLDQTRIGAAVKEVDVRLSALKAKATRLRAEVTGSKRLIFPEGVQRFPDLMKVERALFEQKQT
GLSEELRTLKVAVSLAGEEAELIKELSGSGDVNRTEVIRSARALNDAQAQLINRKNKYLEEVSSELAKAEDEIAQNVQIL
TQRQQQLADSVFIASLPGIVKNVRVTTLGGVLRGGDELMQIIPVDDELIIEAKVSPADIGQVQKGLQATIRFDPFDYTIY
GGVIGEVIYVSGDTLKEETGQGEEIYYRVHVTTQTSPVTTTSGRVLEILPGMTAQVDIKTSDRTVLNYLLKPLRKTLSES
FGER

Sequences:

>Translated_404_residues
MLFDSFFGDDDAGGKEKAARLEGYYRRNYSVVLWVLLLGMIGFGFWSASFRIDQVARATGEVIASSRVQIIQAVDGGVLS
TLNVKEGDRVAKGEVLATLDQTRIGAAVKEVDVRLSALKAKATRLRAEVTGSKRLIFPEGVQRFPDLMKVERALFEQKQT
GLSEELRTLKVAVSLAGEEAELIKELSGSGDVNRTEVIRSARALNDAQAQLINRKNKYLEEVSSELAKAEDEIAQNVQIL
TQRQQQLADSVFIASLPGIVKNVRVTTLGGVLRGGDELMQIIPVDDELIIEAKVSPADIGQVQKGLQATIRFDPFDYTIY
GGVIGEVIYVSGDTLKEETGQGEEIYYRVHVTTQTSPVTTTSGRVLEILPGMTAQVDIKTSDRTVLNYLLKPLRKTLSES
FGER
>Mature_404_residues
MLFDSFFGDDDAGGKEKAARLEGYYRRNYSVVLWVLLLGMIGFGFWSASFRIDQVARATGEVIASSRVQIIQAVDGGVLS
TLNVKEGDRVAKGEVLATLDQTRIGAAVKEVDVRLSALKAKATRLRAEVTGSKRLIFPEGVQRFPDLMKVERALFEQKQT
GLSEELRTLKVAVSLAGEEAELIKELSGSGDVNRTEVIRSARALNDAQAQLINRKNKYLEEVSSELAKAEDEIAQNVQIL
TQRQQQLADSVFIASLPGIVKNVRVTTLGGVLRGGDELMQIIPVDDELIIEAKVSPADIGQVQKGLQATIRFDPFDYTIY
GGVIGEVIYVSGDTLKEETGQGEEIYYRVHVTTQTSPVTTTSGRVLEILPGMTAQVDIKTSDRTVLNYLLKPLRKTLSES
FGER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44358; Mature: 44358

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDSFFGDDDAGGKEKAARLEGYYRRNYSVVLWVLLLGMIGFGFWSASFRIDQVARATG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
EVIASSRVQIIQAVDGGVLSTLNVKEGDRVAKGEVLATLDQTRIGAAVKEVDVRLSALKA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KATRLRAEVTGSKRLIFPEGVQRFPDLMKVERALFEQKQTGLSEELRTLKVAVSLAGEEA
HHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
ELIKELSGSGDVNRTEVIRSARALNDAQAQLINRKNKYLEEVSSELAKAEDEIAQNVQIL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQRQQQLADSVFIASLPGIVKNVRVTTLGGVLRGGDELMQIIPVDDELIIEAKVSPADIG
HHHHHHHHHHHHHHHCCHHHHCCCCEEHHHHHCCCHHHEEEECCCCCEEEEEECCCHHHH
QVQKGLQATIRFDPFDYTIYGGVIGEVIYVSGDTLKEETGQGEEIYYRVHVTTQTSPVTT
HHHHCCEEEEEECCCCEEEECCHHCEEEEECCCCHHHHCCCCCEEEEEEEEEECCCCCEE
TSGRVLEILPGMTAQVDIKTSDRTVLNYLLKPLRKTLSESFGER
CCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFDSFFGDDDAGGKEKAARLEGYYRRNYSVVLWVLLLGMIGFGFWSASFRIDQVARATG
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
EVIASSRVQIIQAVDGGVLSTLNVKEGDRVAKGEVLATLDQTRIGAAVKEVDVRLSALKA
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KATRLRAEVTGSKRLIFPEGVQRFPDLMKVERALFEQKQTGLSEELRTLKVAVSLAGEEA
HHHHHHHEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHH
ELIKELSGSGDVNRTEVIRSARALNDAQAQLINRKNKYLEEVSSELAKAEDEIAQNVQIL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQRQQQLADSVFIASLPGIVKNVRVTTLGGVLRGGDELMQIIPVDDELIIEAKVSPADIG
HHHHHHHHHHHHHHHCCHHHHCCCCEEHHHHHCCCHHHEEEECCCCCEEEEEECCCHHHH
QVQKGLQATIRFDPFDYTIYGGVIGEVIYVSGDTLKEETGQGEEIYYRVHVTTQTSPVTT
HHHHCCEEEEEECCCCEEEECCHHCEEEEECCCCHHHHCCCCCEEEEEEEEEECCCCCEE
TSGRVLEILPGMTAQVDIKTSDRTVLNYLLKPLRKTLSESFGER
CCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]