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The map label for this gene is frp [H]

Identifier: 119946245

GI number: 119946245

Start: 3201973

End: 3202734

Strand: Direct

Name: frp [H]

Synonym: Ping_2607

Alternate gene names: 119946245

Gene position: 3201973-3202734 (Clockwise)

Preceding gene: 119946237

Following gene: 119946246

Centisome position: 70.22

GC content: 40.94

Gene sequence:

>762_bases
ATGCAGGATGTCACTCATTTATTACAATCTCACCGTTCGATTCGTACTTTTAAAGATATTCCGATAGAACAATCCATCGT
GGAAGAATTAATCTGTTCCGGGCAAGCGGCGGCGACCTCCAGTTTTATTCAGGCTTGTACCGTGATTCAGGTATCAAAAG
GCGCTAAACGTGAGAAAATAGCAGAGCTTGCGGGTAACCAGAATTATGTTAAAAAGGCACCCGTATTTCTGGTTTTTTGT
GCAGATATGCACCGCCATCAACTCGCTTGTGAGATGCATAAAGTGCCCATGAAAAGTGGTTATACCGAACAATTATTAAC
CGCATCGATCGATTGTGCTTTATTTGCTCAAAATGTCGTTATTGCCGCAGAAGCATTAGGATTAGGGATTTGTTATATTG
GCGGAATAAGAAATGATATTGCAGCCGTATCATCACTGCTGGACTTACCTGACTTGGCTTTCCCCGTATTTGGTTTATGT
CTGGGTTACCCGGATCAGAATCCTGAAGTAAAACCTCGCTTGCCATTATCGTTAACCCTAAAACAAAATAGTTATTCGCA
ACATAAAACATTAAATGAAGCTGATAAAGACGATATAGCCGCGCTTGAAGCCTATGACCAACAGATTAGGGAGTATTATA
AAAGCAGAACAAGTGCTCAAAAGGAGATGAGTTGGACTGAGCAAATATCAGGAATGCTGCAAAAAGAAGCTAGGCCACAC
ATGATGGACTTTCTTCAAGGCAAAGGATTTATGAAGAGATAA

Upstream 100 bases:

>100_bases
AATAGCGCTAAATTTTCAATCTCCCTTCTGCTGCGTTAAATTATTCATAGAATGTGGTAAAGTCGAGCAGGCTAAAATTA
CCCCACTTTAAGGATATGAT

Downstream 100 bases:

>100_bases
AGGTTCAAAATAAAACCTGTCAGGCCTACCTGACAGTTAATTTACCTGCCTTTTTTAGTCTGTATTCATCGTTGCATTAA
AATTATATAATACATCAAAA

Product: nitroreductase

Products: NA

Alternate protein names: Flavin reductase P; NADPH-FMN oxidoreductase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MQDVTHLLQSHRSIRTFKDIPIEQSIVEELICSGQAAATSSFIQACTVIQVSKGAKREKIAELAGNQNYVKKAPVFLVFC
ADMHRHQLACEMHKVPMKSGYTEQLLTASIDCALFAQNVVIAAEALGLGICYIGGIRNDIAAVSSLLDLPDLAFPVFGLC
LGYPDQNPEVKPRLPLSLTLKQNSYSQHKTLNEADKDDIAALEAYDQQIREYYKSRTSAQKEMSWTEQISGMLQKEARPH
MMDFLQGKGFMKR

Sequences:

>Translated_253_residues
MQDVTHLLQSHRSIRTFKDIPIEQSIVEELICSGQAAATSSFIQACTVIQVSKGAKREKIAELAGNQNYVKKAPVFLVFC
ADMHRHQLACEMHKVPMKSGYTEQLLTASIDCALFAQNVVIAAEALGLGICYIGGIRNDIAAVSSLLDLPDLAFPVFGLC
LGYPDQNPEVKPRLPLSLTLKQNSYSQHKTLNEADKDDIAALEAYDQQIREYYKSRTSAQKEMSWTEQISGMLQKEARPH
MMDFLQGKGFMKR
>Mature_253_residues
MQDVTHLLQSHRSIRTFKDIPIEQSIVEELICSGQAAATSSFIQACTVIQVSKGAKREKIAELAGNQNYVKKAPVFLVFC
ADMHRHQLACEMHKVPMKSGYTEQLLTASIDCALFAQNVVIAAEALGLGICYIGGIRNDIAAVSSLLDLPDLAFPVFGLC
LGYPDQNPEVKPRLPLSLTLKQNSYSQHKTLNEADKDDIAALEAYDQQIREYYKSRTSAQKEMSWTEQISGMLQKEARPH
MMDFLQGKGFMKR

Specific function: Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=253, Percent_Identity=42.6877470355731, Blast_Score=203, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28214; Mature: 28214

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVTHLLQSHRSIRTFKDIPIEQSIVEELICSGQAAATSSFIQACTVIQVSKGAKREKI
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AELAGNQNYVKKAPVFLVFCADMHRHQLACEMHKVPMKSGYTEQLLTASIDCALFAQNVV
HHHHCCCCHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
IAAEALGLGICYIGGIRNDIAAVSSLLDLPDLAFPVFGLCLGYPDQNPEVKPRLPLSLTL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KQNSYSQHKTLNEADKDDIAALEAYDQQIREYYKSRTSAQKEMSWTEQISGMLQKEARPH
ECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MMDFLQGKGFMKR
HHHHHHCCCCCCC
>Mature Secondary Structure
MQDVTHLLQSHRSIRTFKDIPIEQSIVEELICSGQAAATSSFIQACTVIQVSKGAKREKI
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
AELAGNQNYVKKAPVFLVFCADMHRHQLACEMHKVPMKSGYTEQLLTASIDCALFAQNVV
HHHHCCCCHHHHCCEEEEEECHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
IAAEALGLGICYIGGIRNDIAAVSSLLDLPDLAFPVFGLCLGYPDQNPEVKPRLPLSLTL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
KQNSYSQHKTLNEADKDDIAALEAYDQQIREYYKSRTSAQKEMSWTEQISGMLQKEARPH
ECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MMDFLQGKGFMKR
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8206832; 8885832 [H]