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The map label for this gene is yqhD [H]

Identifier: 119946153

GI number: 119946153

Start: 3070987

End: 3072144

Strand: Direct

Name: yqhD [H]

Synonym: Ping_2513

Alternate gene names: 119946153

Gene position: 3070987-3072144 (Clockwise)

Preceding gene: 119946152

Following gene: 119946156

Centisome position: 67.35

GC content: 44.82

Gene sequence:

>1158_bases
ATGAATAACTTCACTTTTTTCAACCCCACCAGAATCCATTTCGGTAAAGGACAAATTGCTAAAATAAAAGAAGAAATTCC
AGCTAATGCAAAGGTGATGCTAACCTACGGCGGTGGCAGTATTAAAAAAAATGGCGTCTATGATCAAGTAATGGACGCAC
TCCAAGGTTACGAGGTGGTTGAATTTAACGGTATTGAACCTAACCCCCATTACGAAACACTGGTTAAGGCCATTGCGCTT
GCTAAAAAGGAAAGCGTCACCTATATCCTTGCAGTGGGAGGAGGCTCTGTCATTGATGGCAGTAAGTTCATCGCTGCTGG
CTCTGTCTATGACGGAGATAGCTGGGACATTATTCAGACTTCCGGCGCCTGCGTTGAAGCCGCTATTCCATTAGGCTGCG
TGCTCACTTTGCCGGCAACCGGTTCGGAAATGAACTGTGGCTCAGTGGTCACTAAAGCGTCGACAAAAGATAAGTTATCT
TTTAAATCAGCGCATGTGCATCCGGTTTTTTCAATTTTAGATCCGCAAACAACCTATACGCTACCAAAACGCCAAATTGC
AAACGGTGCGGTCGATAGCTTTGTGCATACTGTCGAGCAATATATTACCTACCCGGTTAATGCTAAAGTACCGGATCGTT
TAGCTGAATCATTGCTGCTGACCATACTTGAAGATGGGCCAGTCGCACTCGAAGATCCGACCAATTATGATGCGCGGGCA
AATCTGATGTGGGTCTCAACCATGGCGCTCAACGGTACCTTAAAAACAGGGGTGCCGACAGACTGGGCAACCCATATGAT
AGGTCACGAACTGACGGGTCTTTACAATCTTGATCACGCACAAACACTGGCTATTGTGATACCTGCTGTTTGGAAATTTA
AGAAACAGCAAAAAAGAGAAAAATTGCTGCAATATGCTGAACGTGTCTTTGCTCTTCACCAGGGAAGTGAAGAAGAGCGT
ATTGATCTGGCTATCCAAAAAACCGAAGAATTCTTTGTCTTGATGGGCAATCCAACCCGGCTTTCAGCTTACGGTTTAGG
TGAAAAAGATATCCCGGCAGTGCAGGAGAAATTAATACTTCACGGGCTGGTTAAATTGGGTGAACATGGTGATATTACGC
CCAAAGAGGCAGGTGAAATACTTAAACTAGCGCTATAA

Upstream 100 bases:

>100_bases
TTAATATTTAGTCAATTAGATGGGTGTCCAGCTATTTGTTATAGCTGTATCATGTCGCGCCTAATCTGATTAATTTTAAT
TCGCCAACGAAGGAAATAAA

Downstream 100 bases:

>100_bases
TACTGGCCTTTCCTTAATTAAACATGAAAAATAATCCCGGCCCTTGTCGGGATTATTTTTGAGTCAGCAGGAAGAACAAC
AGCGGCTTTTAATGACTCGT

Product: alcohol dehydrogenase, NAD(P)-dependent, iron-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNNFTFFNPTRIHFGKGQIAKIKEEIPANAKVMLTYGGGSIKKNGVYDQVMDALQGYEVVEFNGIEPNPHYETLVKAIAL
AKKESVTYILAVGGGSVIDGSKFIAAGSVYDGDSWDIIQTSGACVEAAIPLGCVLTLPATGSEMNCGSVVTKASTKDKLS
FKSAHVHPVFSILDPQTTYTLPKRQIANGAVDSFVHTVEQYITYPVNAKVPDRLAESLLLTILEDGPVALEDPTNYDARA
NLMWVSTMALNGTLKTGVPTDWATHMIGHELTGLYNLDHAQTLAIVIPAVWKFKKQQKREKLLQYAERVFALHQGSEEER
IDLAIQKTEEFFVLMGNPTRLSAYGLGEKDIPAVQEKLILHGLVKLGEHGDITPKEAGEILKLAL

Sequences:

>Translated_385_residues
MNNFTFFNPTRIHFGKGQIAKIKEEIPANAKVMLTYGGGSIKKNGVYDQVMDALQGYEVVEFNGIEPNPHYETLVKAIAL
AKKESVTYILAVGGGSVIDGSKFIAAGSVYDGDSWDIIQTSGACVEAAIPLGCVLTLPATGSEMNCGSVVTKASTKDKLS
FKSAHVHPVFSILDPQTTYTLPKRQIANGAVDSFVHTVEQYITYPVNAKVPDRLAESLLLTILEDGPVALEDPTNYDARA
NLMWVSTMALNGTLKTGVPTDWATHMIGHELTGLYNLDHAQTLAIVIPAVWKFKKQQKREKLLQYAERVFALHQGSEEER
IDLAIQKTEEFFVLMGNPTRLSAYGLGEKDIPAVQEKLILHGLVKLGEHGDITPKEAGEILKLAL
>Mature_385_residues
MNNFTFFNPTRIHFGKGQIAKIKEEIPANAKVMLTYGGGSIKKNGVYDQVMDALQGYEVVEFNGIEPNPHYETLVKAIAL
AKKESVTYILAVGGGSVIDGSKFIAAGSVYDGDSWDIIQTSGACVEAAIPLGCVLTLPATGSEMNCGSVVTKASTKDKLS
FKSAHVHPVFSILDPQTTYTLPKRQIANGAVDSFVHTVEQYITYPVNAKVPDRLAESLLLTILEDGPVALEDPTNYDARA
NLMWVSTMALNGTLKTGVPTDWATHMIGHELTGLYNLDHAQTLAIVIPAVWKFKKQQKREKLLQYAERVFALHQGSEEER
IDLAIQKTEEFFVLMGNPTRLSAYGLGEKDIPAVQEKLILHGLVKLGEHGDITPKEAGEILKLAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=346, Percent_Identity=24.8554913294798, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789386, Length=375, Percent_Identity=61.3333333333333, Blast_Score=493, Evalue=1e-141,
Organism=Escherichia coli, GI48994951, Length=272, Percent_Identity=26.4705882352941, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789163, Length=365, Percent_Identity=23.5616438356164, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082107, Length=278, Percent_Identity=25.1798561151079, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=277, Percent_Identity=24.5487364620939, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321181, Length=389, Percent_Identity=23.6503856041131, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24657991, Length=357, Percent_Identity=24.9299719887955, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42013; Mature: 42013

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFTFFNPTRIHFGKGQIAKIKEEIPANAKVMLTYGGGSIKKNGVYDQVMDALQGYEVV
CCCCEECCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
EFNGIEPNPHYETLVKAIALAKKESVTYILAVGGGSVIDGSKFIAAGSVYDGDSWDIIQT
EECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCCEEEC
SGACVEAAIPLGCVLTLPATGSEMNCGSVVTKASTKDKLSFKSAHVHPVFSILDPQTTYT
CCCEEEECCCCEEEEECCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHHCCCCCEEC
LPKRQIANGAVDSFVHTVEQYITYPVNAKVPDRLAESLLLTILEDGPVALEDPTNYDARA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
NLMWVSTMALNGTLKTGVPTDWATHMIGHELTGLYNLDHAQTLAIVIPAVWKFKKQQKRE
EEEEEEEEEECCEECCCCCCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHH
KLLQYAERVFALHQGSEEERIDLAIQKTEEFFVLMGNPTRLSAYGLGEKDIPAVQEKLIL
HHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCEEEEECCCCCCCHHHHHHHHH
HGLVKLGEHGDITPKEAGEILKLAL
HHHHHCCCCCCCCHHHHCCCCEECC
>Mature Secondary Structure
MNNFTFFNPTRIHFGKGQIAKIKEEIPANAKVMLTYGGGSIKKNGVYDQVMDALQGYEVV
CCCCEECCCCEEEECCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEE
EFNGIEPNPHYETLVKAIALAKKESVTYILAVGGGSVIDGSKFIAAGSVYDGDSWDIIQT
EECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEECCCCEEEECCCCCCCCCCEEEC
SGACVEAAIPLGCVLTLPATGSEMNCGSVVTKASTKDKLSFKSAHVHPVFSILDPQTTYT
CCCEEEECCCCEEEEECCCCCCCCCCCCEEECCCCCCCCEECCCCCCCHHHHCCCCCEEC
LPKRQIANGAVDSFVHTVEQYITYPVNAKVPDRLAESLLLTILEDGPVALEDPTNYDARA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEE
NLMWVSTMALNGTLKTGVPTDWATHMIGHELTGLYNLDHAQTLAIVIPAVWKFKKQQKRE
EEEEEEEEEECCEECCCCCCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHH
KLLQYAERVFALHQGSEEERIDLAIQKTEEFFVLMGNPTRLSAYGLGEKDIPAVQEKLIL
HHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCEEEEECCCCCCCHHHHHHHHH
HGLVKLGEHGDITPKEAGEILKLAL
HHHHHCCCCCCCCHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]