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The map label for this gene is serB [H]

Identifier: 119946096

GI number: 119946096

Start: 2993470

End: 2994579

Strand: Reverse

Name: serB [H]

Synonym: Ping_2446

Alternate gene names: 119946096

Gene position: 2994579-2993470 (Counterclockwise)

Preceding gene: 119946098

Following gene: 119946083

Centisome position: 65.68

GC content: 37.75

Gene sequence:

>1110_bases
ATGATAAATCGCAATAGTTATGGTGTTAGCCATAATTTAAACCCATTTAGGTGTAGGTATTTTACAGTGAAAGTAATCAA
AAATCTTTGTAACCCTTCAAATTCTCAATCACTGATTCAATGGCGAGATTGTTTAAAAGAAGATCTTAATGAATTAGAAA
ATCTCTTTTACCATCAAGGAAACTTAACGCAAGTATTACTTTCTGATTTTACAGTGAAAGCAGAACTTATTGTGATGGGC
AAACAATTTACAACATTAGATTTACATAACCTACTCACCTTTTTAGAAAATGAAAAAATCGATACGATACAATTATTTGC
ACCTGAAATAATAGAAAATACAGTGGTTATGTGTTTTTCTTTAAATGCTTTCCCTTCCTCTTTAAAGGTTAAGTTAGATA
ATTTTGCAGCAAGGTTTAAGTTAGATTTTGCGTTGATGAAAAATTTCCCTGACTGGGGTAAACCAGGTTTAGTCTTGATG
GACATGGACTCTACCACTATTCAAATAGAGTGTATCGATGAAATTGCACGACTGTTTGGTGTTGGCGAGCAGGTATCAGC
AGTAACGGCTTTGGCGATGCAGGGAAAAATAGATTTTAATGAAAGCTTAAGGACACGAGTTGGTAAATTAGCAGGGGCAC
CTGTTTCAATTTTAAAAGAGGTTGCAGATAATATGCCCTTGATGCCGGGCTTGCTTGAACTCATCAAGGGCTTAAAGAAA
AGTGGTTGGAAAGTGGCTATTGCTTCAGGTGGGTTTAACTATTTTGCAGATCGCTTAAAAGACGACCACGGTTTTGATAT
GGCTGTCGCAAACACCCTGGAAGTTGTCGATCATCATTTAACTGGTCAAGTTGTTGGTGAAATAGTTAACGCCAGCGTCA
AGGCACGGACACTGTCTGAATTAATGGAGCGCTTTGATATTCCAATATCACAAACCGTTGCTATTGGTGATGGGGCTAAT
GATTTAATGATGCTGCAGGCGTCGGCGATGGGTATTGCCATACATGCCAAACCAATAGTACAAGAAAAAGCAGCAGTATC
ACTGAACCATTTGGATTTGTATGGGGTATTGGGCATTTTAAGTGCCAATAAGGGCACTCATTGGCATTAA

Upstream 100 bases:

>100_bases
TACAGATAATCAATAAACTTGAAATTTGTACTGTCCGTAGCAGATAATACATTTTTTTATGCATTTATTATTCCTCAAGA
ACTGGCGGGTAAAACTTGCA

Downstream 100 bases:

>100_bases
ACTTCAATTTTAAGAGGGGTAATTGCAACAGAGGGGGCGATAAGTTTGAGGTTTGAATCAAAATGCGTCTATACCCTATA
AATTGTTAATTAAGCAATAG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MINRNSYGVSHNLNPFRCRYFTVKVIKNLCNPSNSQSLIQWRDCLKEDLNELENLFYHQGNLTQVLLSDFTVKAELIVMG
KQFTTLDLHNLLTFLENEKIDTIQLFAPEIIENTVVMCFSLNAFPSSLKVKLDNFAARFKLDFALMKNFPDWGKPGLVLM
DMDSTTIQIECIDEIARLFGVGEQVSAVTALAMQGKIDFNESLRTRVGKLAGAPVSILKEVADNMPLMPGLLELIKGLKK
SGWKVAIASGGFNYFADRLKDDHGFDMAVANTLEVVDHHLTGQVVGEIVNASVKARTLSELMERFDIPISQTVAIGDGAN
DLMMLQASAMGIAIHAKPIVQEKAAVSLNHLDLYGVLGILSANKGTHWH

Sequences:

>Translated_369_residues
MINRNSYGVSHNLNPFRCRYFTVKVIKNLCNPSNSQSLIQWRDCLKEDLNELENLFYHQGNLTQVLLSDFTVKAELIVMG
KQFTTLDLHNLLTFLENEKIDTIQLFAPEIIENTVVMCFSLNAFPSSLKVKLDNFAARFKLDFALMKNFPDWGKPGLVLM
DMDSTTIQIECIDEIARLFGVGEQVSAVTALAMQGKIDFNESLRTRVGKLAGAPVSILKEVADNMPLMPGLLELIKGLKK
SGWKVAIASGGFNYFADRLKDDHGFDMAVANTLEVVDHHLTGQVVGEIVNASVKARTLSELMERFDIPISQTVAIGDGAN
DLMMLQASAMGIAIHAKPIVQEKAAVSLNHLDLYGVLGILSANKGTHWH
>Mature_369_residues
MINRNSYGVSHNLNPFRCRYFTVKVIKNLCNPSNSQSLIQWRDCLKEDLNELENLFYHQGNLTQVLLSDFTVKAELIVMG
KQFTTLDLHNLLTFLENEKIDTIQLFAPEIIENTVVMCFSLNAFPSSLKVKLDNFAARFKLDFALMKNFPDWGKPGLVLM
DMDSTTIQIECIDEIARLFGVGEQVSAVTALAMQGKIDFNESLRTRVGKLAGAPVSILKEVADNMPLMPGLLELIKGLKK
SGWKVAIASGGFNYFADRLKDDHGFDMAVANTLEVVDHHLTGQVVGEIVNASVKARTLSELMERFDIPISQTVAIGDGAN
DLMMLQASAMGIAIHAKPIVQEKAAVSLNHLDLYGVLGILSANKGTHWH

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=187, Percent_Identity=29.9465240641711, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790849, Length=254, Percent_Identity=50.7874015748031, Blast_Score=257, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=42.2330097087379, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 40898; Mature: 40898

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINRNSYGVSHNLNPFRCRYFTVKVIKNLCNPSNSQSLIQWRDCLKEDLNELENLFYHQG
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NLTQVLLSDFTVKAELIVMGKQFTTLDLHNLLTFLENEKIDTIQLFAPEIIENTVVMCFS
CHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHCCCCCCEEEECCHHHHHCCEEEEEE
LNAFPSSLKVKLDNFAARFKLDFALMKNFPDWGKPGLVLMDMDSTTIQIECIDEIARLFG
CCCCCCCCEEEEHHHHHHHEEHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHC
VGEQVSAVTALAMQGKIDFNESLRTRVGKLAGAPVSILKEVADNMPLMPGLLELIKGLKK
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
SGWKVAIASGGFNYFADRLKDDHGFDMAVANTLEVVDHHLTGQVVGEIVNASVKARTLSE
CCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LMERFDIPISQTVAIGDGANDLMMLQASAMGIAIHAKPIVQEKAAVSLNHLDLYGVLGIL
HHHHHCCCHHHEEEECCCCCCEEEEEECCCEEEEECCHHHHHHHHHEECHHHHHHHHHHH
SANKGTHWH
CCCCCCCCC
>Mature Secondary Structure
MINRNSYGVSHNLNPFRCRYFTVKVIKNLCNPSNSQSLIQWRDCLKEDLNELENLFYHQG
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NLTQVLLSDFTVKAELIVMGKQFTTLDLHNLLTFLENEKIDTIQLFAPEIIENTVVMCFS
CHHHHHHHCCCEEEEEEEECCCCEEHHHHHHHHHHCCCCCCEEEECCHHHHHCCEEEEEE
LNAFPSSLKVKLDNFAARFKLDFALMKNFPDWGKPGLVLMDMDSTTIQIECIDEIARLFG
CCCCCCCCEEEEHHHHHHHEEHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHC
VGEQVSAVTALAMQGKIDFNESLRTRVGKLAGAPVSILKEVADNMPLMPGLLELIKGLKK
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
SGWKVAIASGGFNYFADRLKDDHGFDMAVANTLEVVDHHLTGQVVGEIVNASVKARTLSE
CCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LMERFDIPISQTVAIGDGANDLMMLQASAMGIAIHAKPIVQEKAAVSLNHLDLYGVLGIL
HHHHHCCCHHHEEEECCCCCCEEEEEECCCEEEEECCHHHHHHHHHEECHHHHHHHHHHH
SANKGTHWH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]