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The map label for this gene is ggt [H]

Identifier: 119946049

GI number: 119946049

Start: 2934625

End: 2936370

Strand: Direct

Name: ggt [H]

Synonym: Ping_2396

Alternate gene names: 119946049

Gene position: 2934625-2936370 (Clockwise)

Preceding gene: 119946048

Following gene: 119946055

Centisome position: 64.36

GC content: 44.16

Gene sequence:

>1746_bases
ATGAATAAGAATTTATTGTTGTGCACAGGTGTCGCCCTCCTCTCCTTGAATGTGTTTGCTTCCCCTCAAGTCGCAGACAC
TGTCGCCCCTGAAACCGCTACCTCATATAAACAAAAAACCAGTGTTGTTGCGAATCAATATATGGTTGCAGCTGCACACC
CTCTTGCTGTCGAAGCAGGATACCAAGTATTAAAAAACGGTGGGAATGCAGCTGATGCTTTAGTTGCGGTTCAAACCGTA
CTCGGACTCGTTGAACCTCAATCGTCAGGGTTTGGTGGTGGCGCTTTTCTAGTCTATTACGATGCAAAACTGAAAGTATT
AACCACATTTGACGGGCGTGAAACCGCCCCTTTGGCAGCAAAGCCTGAGTTATTCCAAGACAGCGACGGTAAACCTTTAA
AATTTTATGATGCGGTCGTCGGCGGGCGTTCGGTTGGTACACCGGGAACCGTTAAGTTATTGGCAACGCTGCATGATAAA
TACGGCAGTAAAAAATGGTCAGAACTCTTCCAGCCCGCACAGAAACTTGCCAATAATGGTTTCACTGTTTCAGAAAGATT
AGCCTCTTCCATCGAAAAAGATAAAGCGCGGTTAAGTCGATATCCTGACACCAAAGCGTATTTCTTTACAAAAAATGGCG
AACCTTTATCAGAAGGTAGTTTACTGAAAAATAAAAAGTACGCTGAAACCTTGTCAGTGATAGCTGAGCACGGTGAAAAG
GCTTTCTATCAAGGACAAATAGCAAAAGACATTGTAAATAAAGTGACCGGCATTACTGATAACCCGGGAGTACTCGCGCA
GGAAGATTTTTCAACATATAAAATAATAGAGCGTAAAGCGGTGTGCGCGCCTTACCATCAATATTCTGTCTGCGGCATGG
GACCTCCCAGTTCAGGTGCATTAACTATTGGTCAGATATTAGGTATTGCCAGTCATTTTGATCTGAAAAAACTCGGTGCA
GACAGCCCGGAAGCGTGGCAGATCATTGGTGATGCATCAAGACTCGCTTTTGCTGACCGTGGTCGTTATATGGCTGATTC
TGACTTTGTACCAATGCCCGAGGGGTTGCTTAACTCAGACTATCTTGCCGGGCGAGCAAAATTGATCCAACCAGGTAAAG
CATTATCAGAGGTATCTGCAGGTAACCCACCGTGGAAGAATGCTATCGCGCGGGCAGATGATCAATCCATTGAATTTCCT
TCCACTACCCATATTGTTATTACCGATAAAGAGGGCAATACCCTCTCTATGACCAGTACCGTTGAAAATGGCTTTGGCTC
AAGGGTAATGAGCAATGGTTTTATCCTTAATAACGAGCTGACTGATTTTTCATTTGCGTCATATAAGGATGGCTATCCTA
TCGCTAACCGGGTAGAGCCTGGAAAACGTCCGCGTTCGTCCATGTCTCCAAGCATTATTATGGAAGATGGAAAACCTTAT
ATGGCATTAGGATCTCCCGGTGGCTCACGCATTATCGGATATGTTGCCTCAACTATTATCGCGCATTTAGATTGGGGAAT
GGGAATTCAACAAGCAATAGATTTACCGCATTTAGTGAACCGTTTTGGAACCTATGATATTGAACAAGATACCAAGGCAA
TACGATTTAAAGAAGCGCTTGAGATGATGGGCTATGAAGTGAATATTCGCGATCTAAACTCTGGACTTCACGCAATCCTA
TTTAAAGATGGTAAATTAATCGGCGGCGCAGATCCTCGTCGTGAGGGTATTGCTTTAGGAGATTAA

Upstream 100 bases:

>100_bases
TATCTGCATTCCATTACAAAAATATGGTCTCTAATTTCGAGATAGATATCGATTACCGGATAAATTAATTGGCTAGTTTA
ATGATAAAATAAGGATATTA

Downstream 100 bases:

>100_bases
CGACTGCAGCTCTCAATCAGTTAAAACGCCCGTATGACACCGGCGTTTTTCCACCCATAATAGAACTACAATACAATGAT
AGTTAGTGACGGGAGTTGTT

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MNKNLLLCTGVALLSLNVFASPQVADTVAPETATSYKQKTSVVANQYMVAAAHPLAVEAGYQVLKNGGNAADALVAVQTV
LGLVEPQSSGFGGGAFLVYYDAKLKVLTTFDGRETAPLAAKPELFQDSDGKPLKFYDAVVGGRSVGTPGTVKLLATLHDK
YGSKKWSELFQPAQKLANNGFTVSERLASSIEKDKARLSRYPDTKAYFFTKNGEPLSEGSLLKNKKYAETLSVIAEHGEK
AFYQGQIAKDIVNKVTGITDNPGVLAQEDFSTYKIIERKAVCAPYHQYSVCGMGPPSSGALTIGQILGIASHFDLKKLGA
DSPEAWQIIGDASRLAFADRGRYMADSDFVPMPEGLLNSDYLAGRAKLIQPGKALSEVSAGNPPWKNAIARADDQSIEFP
STTHIVITDKEGNTLSMTSTVENGFGSRVMSNGFILNNELTDFSFASYKDGYPIANRVEPGKRPRSSMSPSIIMEDGKPY
MALGSPGGSRIIGYVASTIIAHLDWGMGIQQAIDLPHLVNRFGTYDIEQDTKAIRFKEALEMMGYEVNIRDLNSGLHAIL
FKDGKLIGGADPRREGIALGD

Sequences:

>Translated_581_residues
MNKNLLLCTGVALLSLNVFASPQVADTVAPETATSYKQKTSVVANQYMVAAAHPLAVEAGYQVLKNGGNAADALVAVQTV
LGLVEPQSSGFGGGAFLVYYDAKLKVLTTFDGRETAPLAAKPELFQDSDGKPLKFYDAVVGGRSVGTPGTVKLLATLHDK
YGSKKWSELFQPAQKLANNGFTVSERLASSIEKDKARLSRYPDTKAYFFTKNGEPLSEGSLLKNKKYAETLSVIAEHGEK
AFYQGQIAKDIVNKVTGITDNPGVLAQEDFSTYKIIERKAVCAPYHQYSVCGMGPPSSGALTIGQILGIASHFDLKKLGA
DSPEAWQIIGDASRLAFADRGRYMADSDFVPMPEGLLNSDYLAGRAKLIQPGKALSEVSAGNPPWKNAIARADDQSIEFP
STTHIVITDKEGNTLSMTSTVENGFGSRVMSNGFILNNELTDFSFASYKDGYPIANRVEPGKRPRSSMSPSIIMEDGKPY
MALGSPGGSRIIGYVASTIIAHLDWGMGIQQAIDLPHLVNRFGTYDIEQDTKAIRFKEALEMMGYEVNIRDLNSGLHAIL
FKDGKLIGGADPRREGIALGD
>Mature_581_residues
MNKNLLLCTGVALLSLNVFASPQVADTVAPETATSYKQKTSVVANQYMVAAAHPLAVEAGYQVLKNGGNAADALVAVQTV
LGLVEPQSSGFGGGAFLVYYDAKLKVLTTFDGRETAPLAAKPELFQDSDGKPLKFYDAVVGGRSVGTPGTVKLLATLHDK
YGSKKWSELFQPAQKLANNGFTVSERLASSIEKDKARLSRYPDTKAYFFTKNGEPLSEGSLLKNKKYAETLSVIAEHGEK
AFYQGQIAKDIVNKVTGITDNPGVLAQEDFSTYKIIERKAVCAPYHQYSVCGMGPPSSGALTIGQILGIASHFDLKKLGA
DSPEAWQIIGDASRLAFADRGRYMADSDFVPMPEGLLNSDYLAGRAKLIQPGKALSEVSAGNPPWKNAIARADDQSIEFP
STTHIVITDKEGNTLSMTSTVENGFGSRVMSNGFILNNELTDFSFASYKDGYPIANRVEPGKRPRSSMSPSIIMEDGKPY
MALGSPGGSRIIGYVASTIIAHLDWGMGIQQAIDLPHLVNRFGTYDIEQDTKAIRFKEALEMMGYEVNIRDLNSGLHAIL
FKDGKLIGGADPRREGIALGD

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=504, Percent_Identity=28.968253968254, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI73915090, Length=504, Percent_Identity=28.968253968254, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI73915096, Length=504, Percent_Identity=28.968253968254, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI73915094, Length=504, Percent_Identity=28.968253968254, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI113429324, Length=505, Percent_Identity=27.9207920792079, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI113429326, Length=509, Percent_Identity=27.8978388998035, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI109148539, Length=538, Percent_Identity=28.2527881040892, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI153266885, Length=498, Percent_Identity=26.7068273092369, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI153266901, Length=499, Percent_Identity=26.25250501002, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI153266907, Length=499, Percent_Identity=24.8496993987976, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI30581157, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI30581155, Length=189, Percent_Identity=32.2751322751323, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1789856, Length=550, Percent_Identity=36.5454545454545, Blast_Score=305, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI193208245, Length=553, Percent_Identity=31.1030741410488, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI193208247, Length=553, Percent_Identity=31.1030741410488, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI72000294, Length=586, Percent_Identity=30.5460750853242, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI212646519, Length=586, Percent_Identity=30.5460750853242, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17542894, Length=571, Percent_Identity=30.6479859894921, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17506189, Length=498, Percent_Identity=29.3172690763052, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI72001495, Length=241, Percent_Identity=27.3858921161826, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI72001497, Length=241, Percent_Identity=27.3858921161826, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17564448, Length=436, Percent_Identity=25.2293577981651, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323330, Length=538, Percent_Identity=26.5799256505576, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161077496, Length=506, Percent_Identity=28.0632411067194, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI18859893, Length=544, Percent_Identity=28.6764705882353, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI161077878, Length=576, Percent_Identity=25.8680555555556, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24642670, Length=539, Percent_Identity=26.3450834879406, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24642666, Length=539, Percent_Identity=26.3450834879406, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45551474, Length=539, Percent_Identity=26.3450834879406, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI161077880, Length=576, Percent_Identity=25.8680555555556, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI18859741, Length=477, Percent_Identity=27.2536687631027, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 62551; Mature: 62551

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNLLLCTGVALLSLNVFASPQVADTVAPETATSYKQKTSVVANQYMVAAAHPLAVEAG
CCCCEEEEECHHHHHEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHH
YQVLKNGGNAADALVAVQTVLGLVEPQSSGFGGGAFLVYYDAKLKVLTTFDGRETAPLAA
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECEEEEEEEECCCCCCCCCC
KPELFQDSDGKPLKFYDAVVGGRSVGTPGTVKLLATLHDKYGSKKWSELFQPAQKLANNG
CCCCCCCCCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
FTVSERLASSIEKDKARLSRYPDTKAYFFTKNGEPLSEGSLLKNKKYAETLSVIAEHGEK
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHCCCH
AFYQGQIAKDIVNKVTGITDNPGVLAQEDFSTYKIIERKAVCAPYHQYSVCGMGPPSSGA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
LTIGQILGIASHFDLKKLGADSPEAWQIIGDASRLAFADRGRYMADSDFVPMPEGLLNSD
EEHHHHHHHHHCCCHHHHCCCCCCCEEEECCHHHHHHHHCCCEECCCCCCCCCCCCCCCC
YLAGRAKLIQPGKALSEVSAGNPPWKNAIARADDQSIEFPSTTHIVITDKEGNTLSMTST
HHCCCHHEECCCHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEHH
VENGFGSRVMSNGFILNNELTDFSFASYKDGYPIANRVEPGKRPRSSMSPSIIMEDGKPY
HHCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCE
MALGSPGGSRIIGYVASTIIAHLDWGMGIQQAIDLPHLVNRFGTYDIEQDTKAIRFKEAL
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHH
EMMGYEVNIRDLNSGLHAILFKDGKLIGGADPRREGIALGD
HHCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNKNLLLCTGVALLSLNVFASPQVADTVAPETATSYKQKTSVVANQYMVAAAHPLAVEAG
CCCCEEEEECHHHHHEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCHHHHHH
YQVLKNGGNAADALVAVQTVLGLVEPQSSGFGGGAFLVYYDAKLKVLTTFDGRETAPLAA
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECEEEEEEEECCCCCCCCCC
KPELFQDSDGKPLKFYDAVVGGRSVGTPGTVKLLATLHDKYGSKKWSELFQPAQKLANNG
CCCCCCCCCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
FTVSERLASSIEKDKARLSRYPDTKAYFFTKNGEPLSEGSLLKNKKYAETLSVIAEHGEK
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHCCHHHHHHHHHHHHCCCH
AFYQGQIAKDIVNKVTGITDNPGVLAQEDFSTYKIIERKAVCAPYHQYSVCGMGPPSSGA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCC
LTIGQILGIASHFDLKKLGADSPEAWQIIGDASRLAFADRGRYMADSDFVPMPEGLLNSD
EEHHHHHHHHHCCCHHHHCCCCCCCEEEECCHHHHHHHHCCCEECCCCCCCCCCCCCCCC
YLAGRAKLIQPGKALSEVSAGNPPWKNAIARADDQSIEFPSTTHIVITDKEGNTLSMTST
HHCCCHHEECCCHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEHH
VENGFGSRVMSNGFILNNELTDFSFASYKDGYPIANRVEPGKRPRSSMSPSIIMEDGKPY
HHCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCE
MALGSPGGSRIIGYVASTIIAHLDWGMGIQQAIDLPHLVNRFGTYDIEQDTKAIRFKEAL
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHH
EMMGYEVNIRDLNSGLHAILFKDGKLIGGADPRREGIALGD
HHCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA