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The map label for this gene is sdcS [H]

Identifier: 119946001

GI number: 119946001

Start: 2847635

End: 2849050

Strand: Reverse

Name: sdcS [H]

Synonym: Ping_2343

Alternate gene names: 119946001

Gene position: 2849050-2847635 (Counterclockwise)

Preceding gene: 119946002

Following gene: 119946000

Centisome position: 62.48

GC content: 40.25

Gene sequence:

>1416_bases
ATGTTAAGTCAATATTTAAAGTACCTGTTACCTGTTTGTATCCCCTTCATTATTCTTATTTTACCCAGCGATAGTTTTGG
TATTGTTGGACTTACCCTAATTGAACAAAGAGTGATCGCGATTTTTGCGCTGGCGACACTTTGCTGGGTATTAGAGCCCA
TCCCTATTTTCGCAACCTCAGTGGTTATTATTGTCTCTGAGTTATTATTAATTTCCGACAAAGGGTTATGGTTTTTTAAA
ACACCCAGCCCGGATTTAGGCCATTTAATCGGTTATCAAACCATTATGGCAACCTTTGCATCTCCTATTATTATGCTTTT
TTTAGGTGGGTTCTTTTTGGCTATGGCGGCAACCAAATATCGCTTAGATGTTAATTTGGCCAGAGTATTACTTAAACCCT
TCGGCAGTAAACCCAAGTATGTGATGTTGGGTCTGATGATGATCACGGCGGTTTTCTCCATGTTTATGAGCAATACTGCA
ACGACAGTCATGATGTTATCCATTTTATCACCGGTTATTGCCCTGCTAGCGACTAAAGACCTAGGCAAAGTTGCATTCTC
GTTATCTGTGCCTGTCGCCGCCAATATTGGTGGCATAGGAACTCCTATTGGCACCCCTCCTAATGCCATCGCATTAAAAT
ATTTAGTCAATGAAAACAGTATTTCCTTTGGGCAATGGATGGTCTTTGGTGTGCCCTTTGTGATGGTGATGTTATTTATC
GCCTGGTTACTATTAATAAAACTGTTTCCAACATCAACGGAGAAAATCAATCTCAATATTAAAGGTAAATTTTTAAAAAC
CCCCAAAGCTATTACGGTTTATATTACCTTTATCGGCACTATTCTATTGTGGTTAATGGGTGATATACATGGCATGAATG
CCTATGTTGTGGCATTAATCCCGGTCGCTGTCTTTGTGACCTTTAAGATTATTAATAAAGAGGATTTAAAGCGCATATCC
TGGGATGTGTTATGGCTGGTATCAGGCGGTATTGCATTAGGTGTCGCGTTAGATAAATCCGGTCTTGCGGAAAATGCGGT
TAATGCAATCCCTTTTGGCAATTTACATCCTCTTTTATTGATCCTTGGCGCCTCCATGTTGTGTTTAGTGATGGCGAATT
TCATCTCCCACACGGCGGCCGCCAATTTATTACTGCCCCTGATTGCTGCATTAGCAACAACAATGCAGTCTTTATTACCC
TATGGTGGTGAAGTTGTCTTAATTCTGGCCGTCACTTTTGCTGCCTCCTTAGGAATGTCATTACCTATCAGTACGCCTCC
TAATGCACTGGCTTATGCATCGGGTAATATTGAAACCAAGCAGATGGCAAAAATAGGCGTGATTATTGGTATTGTTGGTG
TATTGGTCGCTTTTGCTATGTTATTTATTCTGAATAAAACCAATTTTATTGGCTGA

Upstream 100 bases:

>100_bases
GAATACAAAAAGGCTTTTTTGACTTTTAAGTGATCTAATGCAATTTTTTTTATTGTGGTTAATAGACAATTAATTTTTAT
TACAATAAAAAGTTACGTCT

Downstream 100 bases:

>100_bases
GTTATTTTTTATTAAGCAATTTAATTTGAGGAAGCAAAAATGGAAAAAATTAATATTATTTGTGTTGATGATGAACGTGA
AGTCTTGGAATCGGTCAGCC

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLSQYLKYLLPVCIPFIILILPSDSFGIVGLTLIEQRVIAIFALATLCWVLEPIPIFATSVVIIVSELLLISDKGLWFFK
TPSPDLGHLIGYQTIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSKPKYVMLGLMMITAVFSMFMSNTA
TTVMMLSILSPVIALLATKDLGKVAFSLSVPVAANIGGIGTPIGTPPNAIALKYLVNENSISFGQWMVFGVPFVMVMLFI
AWLLLIKLFPTSTEKINLNIKGKFLKTPKAITVYITFIGTILLWLMGDIHGMNAYVVALIPVAVFVTFKIINKEDLKRIS
WDVLWLVSGGIALGVALDKSGLAENAVNAIPFGNLHPLLLILGASMLCLVMANFISHTAAANLLLPLIAALATTMQSLLP
YGGEVVLILAVTFAASLGMSLPISTPPNALAYASGNIETKQMAKIGVIIGIVGVLVAFAMLFILNKTNFIG

Sequences:

>Translated_471_residues
MLSQYLKYLLPVCIPFIILILPSDSFGIVGLTLIEQRVIAIFALATLCWVLEPIPIFATSVVIIVSELLLISDKGLWFFK
TPSPDLGHLIGYQTIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSKPKYVMLGLMMITAVFSMFMSNTA
TTVMMLSILSPVIALLATKDLGKVAFSLSVPVAANIGGIGTPIGTPPNAIALKYLVNENSISFGQWMVFGVPFVMVMLFI
AWLLLIKLFPTSTEKINLNIKGKFLKTPKAITVYITFIGTILLWLMGDIHGMNAYVVALIPVAVFVTFKIINKEDLKRIS
WDVLWLVSGGIALGVALDKSGLAENAVNAIPFGNLHPLLLILGASMLCLVMANFISHTAAANLLLPLIAALATTMQSLLP
YGGEVVLILAVTFAASLGMSLPISTPPNALAYASGNIETKQMAKIGVIIGIVGVLVAFAMLFILNKTNFIG
>Mature_471_residues
MLSQYLKYLLPVCIPFIILILPSDSFGIVGLTLIEQRVIAIFALATLCWVLEPIPIFATSVVIIVSELLLISDKGLWFFK
TPSPDLGHLIGYQTIMATFASPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGSKPKYVMLGLMMITAVFSMFMSNTA
TTVMMLSILSPVIALLATKDLGKVAFSLSVPVAANIGGIGTPIGTPPNAIALKYLVNENSISFGQWMVFGVPFVMVMLFI
AWLLLIKLFPTSTEKINLNIKGKFLKTPKAITVYITFIGTILLWLMGDIHGMNAYVVALIPVAVFVTFKIINKEDLKRIS
WDVLWLVSGGIALGVALDKSGLAENAVNAIPFGNLHPLLLILGASMLCLVMANFISHTAAANLLLPLIAALATTMQSLLP
YGGEVVLILAVTFAASLGMSLPISTPPNALAYASGNIETKQMAKIGVIIGIVGVLVAFAMLFILNKTNFIG

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=480, Percent_Identity=26.875, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI301069349, Length=305, Percent_Identity=26.2295081967213, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI31795546, Length=335, Percent_Identity=24.1791044776119, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI19923838, Length=328, Percent_Identity=25.3048780487805, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI31377715, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI58761541, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI301069346, Length=145, Percent_Identity=30.3448275862069, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI301069353, Length=145, Percent_Identity=30.3448275862069, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4506979, Length=150, Percent_Identity=29.3333333333333, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI225637549, Length=150, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI225637552, Length=150, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786829, Length=450, Percent_Identity=25.5555555555556, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI32565804, Length=408, Percent_Identity=30.3921568627451, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71988385, Length=408, Percent_Identity=30.3921568627451, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71989118, Length=451, Percent_Identity=23.7250554323725, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324340, Length=439, Percent_Identity=29.8405466970387, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319885, Length=447, Percent_Identity=28.8590604026846, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322263, Length=340, Percent_Identity=32.0588235294118, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI281366409, Length=531, Percent_Identity=23.1638418079096, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17737623, Length=531, Percent_Identity=23.1638418079096, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666468, Length=531, Percent_Identity=23.1638418079096, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551633, Length=531, Percent_Identity=23.5404896421846, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50688; Mature: 50688

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQYLKYLLPVCIPFIILILPSDSFGIVGLTLIEQRVIAIFALATLCWVLEPIPIFATS
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VVIIVSELLLISDKGLWFFKTPSPDLGHLIGYQTIMATFASPIIMLFLGGFFLAMAATKY
HHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDVNLARVLLKPFGSKPKYVMLGLMMITAVFSMFMSNTATTVMMLSILSPVIALLATKD
EEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
LGKVAFSLSVPVAANIGGIGTPIGTPPNAIALKYLVNENSISFGQWMVFGVPFVMVMLFI
HHHEEEEEECCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AWLLLIKLFPTSTEKINLNIKGKFLKTPKAITVYITFIGTILLWLMGDIHGMNAYVVALI
HHHHHHHHCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PVAVFVTFKIINKEDLKRISWDVLWLVSGGIALGVALDKSGLAENAVNAIPFGNLHPLLL
HHHHHHHHHHHCHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHCCCCCCCCHHHHHH
ILGASMLCLVMANFISHTAAANLLLPLIAALATTMQSLLPYGGEVVLILAVTFAASLGMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LPISTPPNALAYASGNIETKQMAKIGVIIGIVGVLVAFAMLFILNKTNFIG
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSQYLKYLLPVCIPFIILILPSDSFGIVGLTLIEQRVIAIFALATLCWVLEPIPIFATS
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
VVIIVSELLLISDKGLWFFKTPSPDLGHLIGYQTIMATFASPIIMLFLGGFFLAMAATKY
HHHHHHHHHHEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDVNLARVLLKPFGSKPKYVMLGLMMITAVFSMFMSNTATTVMMLSILSPVIALLATKD
EEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
LGKVAFSLSVPVAANIGGIGTPIGTPPNAIALKYLVNENSISFGQWMVFGVPFVMVMLFI
HHHEEEEEECCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AWLLLIKLFPTSTEKINLNIKGKFLKTPKAITVYITFIGTILLWLMGDIHGMNAYVVALI
HHHHHHHHCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PVAVFVTFKIINKEDLKRISWDVLWLVSGGIALGVALDKSGLAENAVNAIPFGNLHPLLL
HHHHHHHHHHHCHHHHHHHHHHHHEEECCCEEEEEEECCCCCHHHHCCCCCCCCHHHHHH
ILGASMLCLVMANFISHTAAANLLLPLIAALATTMQSLLPYGGEVVLILAVTFAASLGMS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LPISTPPNALAYASGNIETKQMAKIGVIIGIVGVLVAFAMLFILNKTNFIG
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA