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The map label for this gene is sucA [H]

Identifier: 119945913

GI number: 119945913

Start: 2739655

End: 2740368

Strand: Reverse

Name: sucA [H]

Synonym: Ping_2253

Alternate gene names: 119945913

Gene position: 2740368-2739655 (Counterclockwise)

Preceding gene: 119945914

Following gene: 119945912

Centisome position: 60.1

GC content: 37.82

Gene sequence:

>714_bases
ATGCAAGTGAAATTTTCTATTTATCGTTATAACCCTGATGTTGATAACGCGCCCTATATGCAAGATATGTCTTTAGATAT
TGCAGAGGGCTCTGATATGATGGTGCTTGATGCTTTAATGACTCTGAAAGAGAAGGATCCTACCTTATCTTTTCGTCGTT
CATGTCGGGAAGGCGTTTGTGGTTCCGATGGTATGAATATGAATGGTAAAAATGGCTTAGCCTGTATCACTCCATTGTCG
GATTTATTGTCGAAAGGTAAAGTAATATTACGTCCATTACCGGGATTACCCGTAATACGTGATTTAGTCATAGACATGAC
CCAATTTTATACTCAATATGAAAAAATCAAACCCTACTTGATTCCTGATGATCGTCAACCACCCGTTGGAGAGTACAAAC
AAACACCAGAAGAGAGAGAAAAACTCGATGGTTTATATGAATGTATTTTATGTGCTTGTTGTTCAAGTTCTTGTCCTTCT
TTTTGGTGGAATCCAGATAAATTTATTGGTCCTGCCGGTTTATTAGCGGCCTACCGTTTCCTTATCGACAGTCGTGATAA
TGCAACAGAAGAGCGACTTGCAGACTTAGATGATGCATTCAGTGTATTCCGTTGTCATAATATTATGAATTGTGTCAGTG
TTTGTCCCAAAGGATTAAACCCGACAAAAGCAATAGGAAAAATCAAATCAATGTTATTACAACGTGCTATTTAA

Upstream 100 bases:

>100_bases
CCTGAAACCGAAGAGATGTGTAAGCGTGATGTTAATATGAAACCAGTATTGCGTGAACCTTTCCCTCCTAAAGCACGTGT
TTATTAAAAAGGCTATTGTT

Downstream 100 bases:

>100_bases
TTTTTTATGTAATTATAACTAATAAGTAAAAGAAGGAAGAAACTTAAATGCCAACTAATGTTATGAAGACATGGTTAGCT
TCATCCCATTTCTCCGGGGG

Product: succinate dehydrogenase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQVKFSIYRYNPDVDNAPYMQDMSLDIAEGSDMMVLDALMTLKEKDPTLSFRRSCREGVCGSDGMNMNGKNGLACITPLS
DLLSKGKVILRPLPGLPVIRDLVIDMTQFYTQYEKIKPYLIPDDRQPPVGEYKQTPEEREKLDGLYECILCACCSSSCPS
FWWNPDKFIGPAGLLAAYRFLIDSRDNATEERLADLDDAFSVFRCHNIMNCVSVCPKGLNPTKAIGKIKSMLLQRAI

Sequences:

>Translated_237_residues
MQVKFSIYRYNPDVDNAPYMQDMSLDIAEGSDMMVLDALMTLKEKDPTLSFRRSCREGVCGSDGMNMNGKNGLACITPLS
DLLSKGKVILRPLPGLPVIRDLVIDMTQFYTQYEKIKPYLIPDDRQPPVGEYKQTPEEREKLDGLYECILCACCSSSCPS
FWWNPDKFIGPAGLLAAYRFLIDSRDNATEERLADLDDAFSVFRCHNIMNCVSVCPKGLNPTKAIGKIKSMLLQRAI
>Mature_237_residues
MQVKFSIYRYNPDVDNAPYMQDMSLDIAEGSDMMVLDALMTLKEKDPTLSFRRSCREGVCGSDGMNMNGKNGLACITPLS
DLLSKGKVILRPLPGLPVIRDLVIDMTQFYTQYEKIKPYLIPDDRQPPVGEYKQTPEEREKLDGLYECILCACCSSSCPS
FWWNPDKFIGPAGLLAAYRFLIDSRDNATEERLADLDDAFSVFRCHNIMNCVSVCPKGLNPTKAIGKIKSMLLQRAI

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=58.1896551724138, Blast_Score=270, Evalue=1e-72,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=78.3898305084746, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=40.5172413793103, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17533915, Length=234, Percent_Identity=53.8461538461538, Blast_Score=252, Evalue=9e-68,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=53.0434782608696, Blast_Score=248, Evalue=6e-67,
Organism=Drosophila melanogaster, GI17137106, Length=237, Percent_Identity=55.6962025316456, Blast_Score=264, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=53.448275862069, Blast_Score=248, Evalue=3e-66,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26657; Mature: 26657

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKFSIYRYNPDVDNAPYMQDMSLDIAEGSDMMVLDALMTLKEKDPTLSFRRSCREGVC
CCEEEEEEEECCCCCCCCCHHCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGMNMNGKNGLACITPLSDLLSKGKVILRPLPGLPVIRDLVIDMTQFYTQYEKIKPYL
CCCCCCCCCCCCEEEECCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
IPDDRQPPVGEYKQTPEEREKLDGLYECILCACCSSSCPSFWWNPDKFIGPAGLLAAYRF
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHH
LIDSRDNATEERLADLDDAFSVFRCHNIMNCVSVCPKGLNPTKAIGKIKSMLLQRAI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVKFSIYRYNPDVDNAPYMQDMSLDIAEGSDMMVLDALMTLKEKDPTLSFRRSCREGVC
CCEEEEEEEECCCCCCCCCHHCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCC
GSDGMNMNGKNGLACITPLSDLLSKGKVILRPLPGLPVIRDLVIDMTQFYTQYEKIKPYL
CCCCCCCCCCCCEEEECCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCC
IPDDRQPPVGEYKQTPEEREKLDGLYECILCACCSSSCPSFWWNPDKFIGPAGLLAAYRF
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHH
LIDSRDNATEERLADLDDAFSVFRCHNIMNCVSVCPKGLNPTKAIGKIKSMLLQRAI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]