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The map label for this gene is nlpI [H]

Identifier: 119945870

GI number: 119945870

Start: 2692387

End: 2693304

Strand: Reverse

Name: nlpI [H]

Synonym: Ping_2210

Alternate gene names: 119945870

Gene position: 2693304-2692387 (Counterclockwise)

Preceding gene: 119945871

Following gene: 119945867

Centisome position: 59.07

GC content: 34.97

Gene sequence:

>918_bases
ATGAGATTTCATTGTTCATTATTGTTCGTTTTACCTATTTTATTTACATTAACAGCTTGCCAAAGCCTTCCTAATACTGA
GCAGGATTTTTCAACGCAAAATAATGTAATTAATAAATTCCCTCTCTCTACAGCTGTGCAAATAGACTATCAAGATGAAG
TTAAATTGTTAAAAATTAATCAATTACTTGTTGAACAAAAAGATCTGGATGCAAGACAGTACGCAGTATTATTTTATGAA
CGTGGGGTTATTTATGACCGAATGGGCTTGGCAGCACATAGTCGTTATGATTTTATCCAAGCGTTGAGTGTTGATCCTAC
CTTTGCAGATGCTTATAACTTTTTAGGGCTTTATCTATTATTATCCGAATCCTATGATGAGGCATTTGATGCTTTTGATT
CGGCATTAGAGTTATCCGATAATATGCAATACAGTTATTTGCATAGGGCAGTTGGGCTGTATCAAATCGGACGTTATCAA
TTAGCGATGAATGATATTGAAAAGTTCTATTCGCTTGATCAAAATGATCCCTATCGGGTTTTGTGGCGTTTCATTATTAA
CAGTAAAGTCGATCAGTTAAAAGCGTTACAGACACTTAAATCATCAACTCAATTAAGTAATGATCCTCGCTTTGCCTGGG
CAATCGTTGATGTGATAGCGGGCAGAACAACAGAAAAAGATTTTCTTGAAAGTCTCTCTTATGGTGTTAACACCAATAAA
GAACTTGCTGAGCGTCTATGTGAGGCCTATTTTTATCTTGCTCATTGGCATCAATTGTCAGGCCATTTAGAGAAAGCGGT
CTATTACTTTAAATTAAGTACCGCGACAAATATTCATGAGTTTATTGAATATAAGTATGCATTGATAGAGTTAGGTGCAA
TTCAAAGAAGGTTGCAGACTGGTAAAGATAAAAAATAA

Upstream 100 bases:

>100_bases
AGCACTGCATGCAGTGCTTTTTTTATTTCAAAATATATCTAACTTTACTTTCAGCTTGTTATAGTTCACTCTTAACTCAC
TTGTCTTAAAGGGTTTGTTC

Downstream 100 bases:

>100_bases
CCCCGTTGCTTACATGTTGCAGTGACTTTTTATAAAAAAGGTAGCCAATGGTTACCTTTTTAGTTAGATAATATGTTAGT
TAATCACTAAAGATTATCTA

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRFHCSLLFVLPILFTLTACQSLPNTEQDFSTQNNVINKFPLSTAVQIDYQDEVKLLKINQLLVEQKDLDARQYAVLFYE
RGVIYDRMGLAAHSRYDFIQALSVDPTFADAYNFLGLYLLLSESYDEAFDAFDSALELSDNMQYSYLHRAVGLYQIGRYQ
LAMNDIEKFYSLDQNDPYRVLWRFIINSKVDQLKALQTLKSSTQLSNDPRFAWAIVDVIAGRTTEKDFLESLSYGVNTNK
ELAERLCEAYFYLAHWHQLSGHLEKAVYYFKLSTATNIHEFIEYKYALIELGAIQRRLQTGKDKK

Sequences:

>Translated_305_residues
MRFHCSLLFVLPILFTLTACQSLPNTEQDFSTQNNVINKFPLSTAVQIDYQDEVKLLKINQLLVEQKDLDARQYAVLFYE
RGVIYDRMGLAAHSRYDFIQALSVDPTFADAYNFLGLYLLLSESYDEAFDAFDSALELSDNMQYSYLHRAVGLYQIGRYQ
LAMNDIEKFYSLDQNDPYRVLWRFIINSKVDQLKALQTLKSSTQLSNDPRFAWAIVDVIAGRTTEKDFLESLSYGVNTNK
ELAERLCEAYFYLAHWHQLSGHLEKAVYYFKLSTATNIHEFIEYKYALIELGAIQRRLQTGKDKK
>Mature_305_residues
MRFHCSLLFVLPILFTLTACQSLPNTEQDFSTQNNVINKFPLSTAVQIDYQDEVKLLKINQLLVEQKDLDARQYAVLFYE
RGVIYDRMGLAAHSRYDFIQALSVDPTFADAYNFLGLYLLLSESYDEAFDAFDSALELSDNMQYSYLHRAVGLYQIGRYQ
LAMNDIEKFYSLDQNDPYRVLWRFIINSKVDQLKALQTLKSSTQLSNDPRFAWAIVDVIAGRTTEKDFLESLSYGVNTNK
ELAERLCEAYFYLAHWHQLSGHLEKAVYYFKLSTATNIHEFIEYKYALIELGAIQRRLQTGKDKK

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=250, Percent_Identity=39.6, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 35466; Mature: 35466

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHCSLLFVLPILFTLTACQSLPNTEQDFSTQNNVINKFPLSTAVQIDYQDEVKLLKIN
CCEEHHHHHHHHHHHHHHHHHHCCCCHHHHCHHCCCHHCCCCCEEEEECCCCCCHHHHHH
QLLVEQKDLDARQYAVLFYERGVIYDRMGLAAHSRYDFIQALSVDPTFADAYNFLGLYLL
HHHHHHHCCCHHHHEEEEEECCCHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSESYDEAFDAFDSALELSDNMQYSYLHRAVGLYQIGRYQLAMNDIEKFYSLDQNDPYRV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LWRFIINSKVDQLKALQTLKSSTQLSNDPRFAWAIVDVIAGRTTEKDFLESLSYGVNTNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
ELAERLCEAYFYLAHWHQLSGHLEKAVYYFKLSTATNIHEFIEYKYALIELGAIQRRLQT
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
GKDKK
CCCCC
>Mature Secondary Structure
MRFHCSLLFVLPILFTLTACQSLPNTEQDFSTQNNVINKFPLSTAVQIDYQDEVKLLKIN
CCEEHHHHHHHHHHHHHHHHHHCCCCHHHHCHHCCCHHCCCCCEEEEECCCCCCHHHHHH
QLLVEQKDLDARQYAVLFYERGVIYDRMGLAAHSRYDFIQALSVDPTFADAYNFLGLYLL
HHHHHHHCCCHHHHEEEEEECCCHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSESYDEAFDAFDSALELSDNMQYSYLHRAVGLYQIGRYQLAMNDIEKFYSLDQNDPYRV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LWRFIINSKVDQLKALQTLKSSTQLSNDPRFAWAIVDVIAGRTTEKDFLESLSYGVNTNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCH
ELAERLCEAYFYLAHWHQLSGHLEKAVYYFKLSTATNIHEFIEYKYALIELGAIQRRLQT
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHC
GKDKK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]