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The map label for this gene is moaB [H]

Identifier: 119945830

GI number: 119945830

Start: 2645705

End: 2646220

Strand: Reverse

Name: moaB [H]

Synonym: Ping_2170

Alternate gene names: 119945830

Gene position: 2646220-2645705 (Counterclockwise)

Preceding gene: 119945831

Following gene: 119945829

Centisome position: 58.04

GC content: 43.6

Gene sequence:

>516_bases
ATGAGTCACCTTTCAACACAAGCATTTAAAGCCGCAAAGATGGCTGTATTAACCGTTTCTGATACGCGTAATGAAGAAAC
CGATACCTCGGGCGGTTACCTTGCTCAAGCATTACAACAAGCAGGCCATTTACTGGCGGATAAAAAGATTGTTATTGATG
ATCTCTATAAAATTCGTGCCATTGTCTCGAATTGGATTGCCGATCCGGAAATTGAAGCTGTATTAATCACCGGCGGCACT
GGTTTTACTTCTCGCGATACCACCCCTGAAGCGGTAGCGGTTTTATTTGACAAAGAGGTTGAAGGTTTTGGTGAACTTTT
TCGCCATGTGTCCTATCAGGAAATTGGTTCATCGACTATTCAAAGTCGGGCAGTGGCGGGTTTTGCCAATAAGACGGTTA
TTTTCTGTATGCCGGGCTCTACCGGGGCCTGTAAAACCGCCTGGTCGAAAATAATTGTTGAACAGTTAAACTCTCAGCAT
AAACCCTGTAATTTTATGCCCCATATTGGTCTTTAA

Upstream 100 bases:

>100_bases
TAAAACAGCAGGATTGCAGATTCCATAATAGTAATACCCCGGATCAATGGTTAAGCTGTCTGGAAATCCATCAACAACTG
CAAAATACTAAGGAATAAAG

Downstream 100 bases:

>100_bases
GTCGGTGAACATAGTTAGAAACATCTTTACAATTTAATGTTTCTAACTATTAATATAATAGATAAACGTAGTGTTGATTT
GCATGTTCGAACACTTATAA

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSHLSTQAFKAAKMAVLTVSDTRNEETDTSGGYLAQALQQAGHLLADKKIVIDDLYKIRAIVSNWIADPEIEAVLITGGT
GFTSRDTTPEAVAVLFDKEVEGFGELFRHVSYQEIGSSTIQSRAVAGFANKTVIFCMPGSTGACKTAWSKIIVEQLNSQH
KPCNFMPHIGL

Sequences:

>Translated_171_residues
MSHLSTQAFKAAKMAVLTVSDTRNEETDTSGGYLAQALQQAGHLLADKKIVIDDLYKIRAIVSNWIADPEIEAVLITGGT
GFTSRDTTPEAVAVLFDKEVEGFGELFRHVSYQEIGSSTIQSRAVAGFANKTVIFCMPGSTGACKTAWSKIIVEQLNSQH
KPCNFMPHIGL
>Mature_170_residues
SHLSTQAFKAAKMAVLTVSDTRNEETDTSGGYLAQALQQAGHLLADKKIVIDDLYKIRAIVSNWIADPEIEAVLITGGTG
FTSRDTTPEAVAVLFDKEVEGFGELFRHVSYQEIGSSTIQSRAVAGFANKTVIFCMPGSTGACKTAWSKIIVEQLNSQHK
PCNFMPHIGL

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=147, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI66932975, Length=147, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787000, Length=169, Percent_Identity=59.1715976331361, Blast_Score=211, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17564954, Length=148, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136978, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24638841, Length=149, Percent_Identity=34.2281879194631, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18520; Mature: 18389

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLSTQAFKAAKMAVLTVSDTRNEETDTSGGYLAQALQQAGHLLADKKIVIDDLYKIRA
CCCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IVSNWIADPEIEAVLITGGTGFTSRDTTPEAVAVLFDKEVEGFGELFRHVSYQEIGSSTI
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QSRAVAGFANKTVIFCMPGSTGACKTAWSKIIVEQLNSQHKPCNFMPHIGL
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SHLSTQAFKAAKMAVLTVSDTRNEETDTSGGYLAQALQQAGHLLADKKIVIDDLYKIRA
CCCHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IVSNWIADPEIEAVLITGGTGFTSRDTTPEAVAVLFDKEVEGFGELFRHVSYQEIGSSTI
HHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QSRAVAGFANKTVIFCMPGSTGACKTAWSKIIVEQLNSQHKPCNFMPHIGL
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]