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The map label for this gene is moaC

Identifier: 119945829

GI number: 119945829

Start: 2645103

End: 2645582

Strand: Reverse

Name: moaC

Synonym: Ping_2169

Alternate gene names: 119945829

Gene position: 2645582-2645103 (Counterclockwise)

Preceding gene: 119945830

Following gene: 119945828

Centisome position: 58.02

GC content: 43.75

Gene sequence:

>480_bases
ATGACTCATTTATTTACCCACATTAATCAAGACGGCAAAGCCAATATGGTTGATGTAACGGACAAAAACACCACACAGCG
TCAAGCCATCGCGCAGGCCTATGTGGAAATGAAAGCTGAAACCCTGGCATTAATTTTGAACGGGCAACACCATAAGGGTG
ATGTTTTTGCCACTGCCCGTATTGCCGGCATTATGGCGGCAAAAAAAACATCTGATATTATCCCACTTTGTCACCCTTTA
GCGCTAACTAAAGTAGAGGTAGAGTTGGTGGCAGAGCCTGAATTTAACCGTGTGCGTATTCAAAGCTTATGTAAGTTAAG
CGGCAAAACAGGGGTTGAAATGGAAGCTTTGACGGCCGCATCCGTGGCCGCATTAACGATTTATGATATGTGTAAAGCGA
TACAAAAAGATATGGTGATAACTCAGGTCAAACTGCTTGAAAAAACCGGTGGTAAATCAGGGCACTTTACATCCCAGTGA

Upstream 100 bases:

>100_bases
ATCTTTACAATTTAATGTTTCTAACTATTAATATAATAGATAAACGTAGTGTTGATTTGCATGTTCGAACACTTATAAGC
CATTACTTAGAAGGTAACTT

Downstream 100 bases:

>100_bases
ATAAGGAATTTTGATGATTAACGTTTTATTTTTTGCACAAATACGTGATCAGTTAGGCGTCAGTGGACTACAGCTGCCGA
GCGCTGAAAATAACGATTTG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTHLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATARIAGIMAAKKTSDIIPLCHPL
ALTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAASVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ

Sequences:

>Translated_159_residues
MTHLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATARIAGIMAAKKTSDIIPLCHPL
ALTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAASVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ
>Mature_158_residues
THLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATARIAGIMAAKKTSDIIPLCHPLA
LTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAASVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=73.0263157894737, Blast_Score=234, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI32566331, Length=155, Percent_Identity=43.2258064516129, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=51.3513513513513, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=51.8248175182482, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_PSYIN (A1SWP5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943509.1
- ProteinModelPortal:   A1SWP5
- SMR:   A1SWP5
- STRING:   A1SWP5
- GeneID:   4625955
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2169
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   A1SWP5
- BioCyc:   PING357804:PING_2169-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17307; Mature: 17176

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATAR
CCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHH
IAGIMAAKKTSDIIPLCHPLALTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAA
HHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
SVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
THLFTHINQDGKANMVDVTDKNTTQRQAIAQAYVEMKAETLALILNGQHHKGDVFATAR
CCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHH
IAGIMAAKKTSDIIPLCHPLALTKVEVELVAEPEFNRVRIQSLCKLSGKTGVEMEALTAA
HHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
SVAALTIYDMCKAIQKDMVITQVKLLEKTGGKSGHFTSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA