Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 119945827

GI number: 119945827

Start: 2644392

End: 2644838

Strand: Reverse

Name: moaE [H]

Synonym: Ping_2167

Alternate gene names: 119945827

Gene position: 2644838-2644392 (Counterclockwise)

Preceding gene: 119945828

Following gene: 119945826

Centisome position: 58.01

GC content: 43.4

Gene sequence:

>447_bases
ATGATCCGGGTGCAAACTGAAGATTTTAACCAACAGCGTGAATACGATCGTTTACGTGAACAATCGAGCGTCGGCGCAGT
GGTCACCTTTACAGGGTTAGTACGTGATTTTAATCAGGGAGAACAGGTGGCAAGTTTAACCCTGGAGCATTATCCATTGA
TGACAGAAAAATCATTAGCTCAAATCGTGATGCAGGCGAAGCAGCGCTGGAATATTCTGGCTTGTACTTTGATTCATCGT
GTTGGTGAGTTAAAAATAAGTGAACAAATTGTTTTTGTTGGTATCGCCACAGCACATCGCCAGGACGCTTTTGCGGCCTG
TGAATACATTATGGATTATCTTAAAACAGAGGCCCCTTTTTGGAAAAAAGAGTGTAACAGTCAGGGGACAAGTTATTGGG
TGGATGCGCGAGAATCAGACCGCAGTGCATTGAATAAATGGTCATAA

Upstream 100 bases:

>100_bases
CATTAATGGTTGCTGTCAATCAAACCATGCAGGCAGATAATGTCCCGCTTTATAGTGGTGATGAAGTTGCATTTTTTCCT
CCTGTCACGGGAGGTTAGTG

Downstream 100 bases:

>100_bases
AAATGACTAAAAAATTGTTCATGAAAATGACCATCTGCCTGCTTCTTTTAATGTTACTTTACAGTTTTTCAGTACAAGCG
AGTATTAAAGTTGCGGTAGC

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MIRVQTEDFNQQREYDRLREQSSVGAVVTFTGLVRDFNQGEQVASLTLEHYPLMTEKSLAQIVMQAKQRWNILACTLIHR
VGELKISEQIVFVGIATAHRQDAFAACEYIMDYLKTEAPFWKKECNSQGTSYWVDARESDRSALNKWS

Sequences:

>Translated_148_residues
MIRVQTEDFNQQREYDRLREQSSVGAVVTFTGLVRDFNQGEQVASLTLEHYPLMTEKSLAQIVMQAKQRWNILACTLIHR
VGELKISEQIVFVGIATAHRQDAFAACEYIMDYLKTEAPFWKKECNSQGTSYWVDARESDRSALNKWS
>Mature_148_residues
MIRVQTEDFNQQREYDRLREQSSVGAVVTFTGLVRDFNQGEQVASLTLEHYPLMTEKSLAQIVMQAKQRWNILACTLIHR
VGELKISEQIVFVGIATAHRQDAFAACEYIMDYLKTEAPFWKKECNSQGTSYWVDARESDRSALNKWS

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=108, Percent_Identity=31.4814814814815, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=54.1095890410959, Blast_Score=164, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17509279, Length=115, Percent_Identity=33.0434782608696, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356259, Length=124, Percent_Identity=33.8709677419355, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17112; Mature: 17112

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVQTEDFNQQREYDRLREQSSVGAVVTFTGLVRDFNQGEQVASLTLEHYPLMTEKSLA
CEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
QIVMQAKQRWNILACTLIHRVGELKISEQIVFVGIATAHRQDAFAACEYIMDYLKTEAPF
HHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCH
WKKECNSQGTSYWVDARESDRSALNKWS
HHHHHCCCCCEEEEECCCCHHHHHCCCC
>Mature Secondary Structure
MIRVQTEDFNQQREYDRLREQSSVGAVVTFTGLVRDFNQGEQVASLTLEHYPLMTEKSLA
CEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
QIVMQAKQRWNILACTLIHRVGELKISEQIVFVGIATAHRQDAFAACEYIMDYLKTEAPF
HHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCH
WKKECNSQGTSYWVDARESDRSALNKWS
HHHHHCCCCCEEEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]