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The map label for this gene is polB [H]

Identifier: 119945553

GI number: 119945553

Start: 2255913

End: 2258342

Strand: Direct

Name: polB [H]

Synonym: Ping_1857

Alternate gene names: 119945553

Gene position: 2255913-2258342 (Clockwise)

Preceding gene: 119945552

Following gene: 119945554

Centisome position: 49.48

GC content: 44.4

Gene sequence:

>2430_bases
ATGTCAGGATCACAGCGGCATCAAATTGCAGGGTTAATTCTCACCCGCCGGCAACATGAAACGCCGCAAGGCGTGGAGTT
GGAGCTGTGGCTTGCGACGAAAGAGGGGCCCTGCCGGGTGTTCTTACCTGCACAACGTTATGTGTTTCTTATTCACCAGC
AACAGCTTGTTAAGGCGCAGGCACTATGGTCAGCGGTGCATTTGACCCCTAATGAAATTCGTCCTCTCTCTTTGACCTCT
TTTAACGGATTATCGGTTAGCGCTATTTATTGCCTTAATAACAAAATGTTCAGACAACTTCAGGATATTTTAACCACTGC
GTCCATTCCGATTTTTGAAGCCGATATTAAGGTCTGTGACCGTTATCTGATGGAGCGTTTTATCTATGGCACTGTCTCTG
TGCAGGGGGAATGCCATTGGCAAGGGCATTACTGGCACTGCCGGGCCGCAAAAATTTCACCTGCCACAGTAACATCCAAG
CTTAAACAGGTCTCATTGGATATTGAATGCAGCCCCTTGGGGGAACTTTATTCGGTTGGGCTTAGCTACGGCAATACTGA
CTCTGATAAGGGAAGCGCATTGTTGGACAGCGATTGCTGCGCAACGGTACTGATGATTGGGGAACATGAACCCTGTGATG
ATATTAATATTCAATGGGTTGCAAATGAACAAGCCTTATTGTGCGCATTAGAAGCTTGGTTTCAATGGCATGACCCGGAT
GCGGTTATTGGCTGGGCAGTTACAAACTTTGATCTGCGCCTATTAGTCAAACGGGCTGATGCACACAATATGCCCTTAAG
ACTTGGGCGAGACGGCTCAGCATTACGCTGGTTACCACACCGTCAAGCTCCAGATCAAGGCACGGTTATTTTAAATGGCA
GAGTGGTCTTAGAGGGTATTGATCAACTTAAAAATGCGGGCTGGATGTTTGAAAGTTTTAGTCTGGAATTTGTCAGTCAA
GCGATGTTATCTGCAGGAAAACTGCTTACTAATCCGCATAACTACAATCATAACAAGGGCTTGGAGATAAAACGTCAATT
TGAGCAGGAGCCTGTCTCACTGGCGCGTTATAATCTGCAGGACTGTTTGCTGGTGGAACGCATATTTGCCAAGGCACAAT
TAACGGAATATGCAATACAACGTGCCCGATTAACCGGTTTAGCACTGGATCGCAGGGGCGCATCGGTTGCGGCCTTTACT
AATCTTTACCTGCCGTTATTACATCGTAGTGGTTATATCGCACCTAATATTGGTGATATTGAAGCACAACATTCACCCGG
TGGCTTTGTTATGGATTCAATACCGGGTCTTTATGATTGGGTATTAGTGCTGGATTTTAAATCATTATACCCCTCTATTA
TTCGCAGCTTTAAAATTGATCCGATGGGCATGATTGAAGGGCTTAAAGAAAATGAAAAAAATGCTATTCCTGGCTTTAGA
GGGGCAAGATTTAGCCGTAATAAACACCATTTACCGGATATTCTGGACAAGCTCACCGCGGCAAGGGAGTCAGCTAAAAA
AGAAAATAATCAACCCTTTCAACATGCGATTAAAATCATTATGAACAGTATGTATGGGGTACTAGGATCCGCGGGTTGCC
GTTTTCACGATACCCGTCTAGCCAGTTCAATTACCCTGCGCGGCCATCAAATTATGCTGGAAACGCGCGATTTTATTGAA
CAACAGGGCGAGCAGGTGGTTTACGGGGATACTGATTCAACCTTTGTTTGGTTAAAGCACTGCACTAATGCCATTGATGC
ACAAGCGCGGGGAAAAGTGCTTGAAAAACGCATTAACCAATATTGGTCGAATAAACTGAACTTGGAATTCCAATTAGATT
GTTTTCTGGAAATTGAATTTGAAACCTGTTTCAGGAAATTTTTTATGCCGACATTACGGGGATCTGAGACCGGCTCTAAA
AAACGTTATGCTGGACTAAAAGTGACCAATGACGGTGAGTTAATGCTATTTAAAGGGTTAGAAACGGTGCGTTCGGATTG
GACCGAACTTGCTCAGGATTTTCAGAAAAAGTTGTATGCTAAAGTGTTTGCCAATGAGCCGATAGATAGCTTGGTAATTG
ATACGGTTGAGTTGTTAAATAAGGGAGAGCTTGATCAGCAGTTAATTTATCACAAGCGCCTGGGGCGTCCTTTGAATGCG
TATCTTAAAAATGTGCCTCCGCAGGTACGGGCTGCACGTTTGGCCGATCAGATTAATGCAAATTTAGGCCGTCCACTGCA
ATACCAGCGTTCAGGCCGGATTGCTTATCTGATCACTGTCAATGGACCCGAGCCTGCAGATTATCGGCAATCCTGCATTG
ATTATCAGCACTATATAGATAAGCAGCTTAAACCGATAGCGGAAGCTATTCTACCTTTGCTTAGCAAAAACTTTGATGAC
ATGATCTCAGATCAAATGCGTTTGTTTTAA

Upstream 100 bases:

>100_bases
ATCAGCAATAATTGAGGTCAGCAGTAATTGATCAGCAGCAATTGCAGTTATTTATTAGTGATACTTTCATTAATTTTCTA
TTTTGAGGTCAGTTAATTTT

Downstream 100 bases:

>100_bases
TTCTATAATTTATTGTAATTCTATAATTTATTTTAATGCTATAAAAGGACAGTTAATAAAATGATGCCGCATTTCAGCGA
CATTAACGCATTTTTAACAT

Product: DNA polymerase II

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 809; Mature: 808

Protein sequence:

>809_residues
MSGSQRHQIAGLILTRRQHETPQGVELELWLATKEGPCRVFLPAQRYVFLIHQQQLVKAQALWSAVHLTPNEIRPLSLTS
FNGLSVSAIYCLNNKMFRQLQDILTTASIPIFEADIKVCDRYLMERFIYGTVSVQGECHWQGHYWHCRAAKISPATVTSK
LKQVSLDIECSPLGELYSVGLSYGNTDSDKGSALLDSDCCATVLMIGEHEPCDDINIQWVANEQALLCALEAWFQWHDPD
AVIGWAVTNFDLRLLVKRADAHNMPLRLGRDGSALRWLPHRQAPDQGTVILNGRVVLEGIDQLKNAGWMFESFSLEFVSQ
AMLSAGKLLTNPHNYNHNKGLEIKRQFEQEPVSLARYNLQDCLLVERIFAKAQLTEYAIQRARLTGLALDRRGASVAAFT
NLYLPLLHRSGYIAPNIGDIEAQHSPGGFVMDSIPGLYDWVLVLDFKSLYPSIIRSFKIDPMGMIEGLKENEKNAIPGFR
GARFSRNKHHLPDILDKLTAARESAKKENNQPFQHAIKIIMNSMYGVLGSAGCRFHDTRLASSITLRGHQIMLETRDFIE
QQGEQVVYGDTDSTFVWLKHCTNAIDAQARGKVLEKRINQYWSNKLNLEFQLDCFLEIEFETCFRKFFMPTLRGSETGSK
KRYAGLKVTNDGELMLFKGLETVRSDWTELAQDFQKKLYAKVFANEPIDSLVIDTVELLNKGELDQQLIYHKRLGRPLNA
YLKNVPPQVRAARLADQINANLGRPLQYQRSGRIAYLITVNGPEPADYRQSCIDYQHYIDKQLKPIAEAILPLLSKNFDD
MISDQMRLF

Sequences:

>Translated_809_residues
MSGSQRHQIAGLILTRRQHETPQGVELELWLATKEGPCRVFLPAQRYVFLIHQQQLVKAQALWSAVHLTPNEIRPLSLTS
FNGLSVSAIYCLNNKMFRQLQDILTTASIPIFEADIKVCDRYLMERFIYGTVSVQGECHWQGHYWHCRAAKISPATVTSK
LKQVSLDIECSPLGELYSVGLSYGNTDSDKGSALLDSDCCATVLMIGEHEPCDDINIQWVANEQALLCALEAWFQWHDPD
AVIGWAVTNFDLRLLVKRADAHNMPLRLGRDGSALRWLPHRQAPDQGTVILNGRVVLEGIDQLKNAGWMFESFSLEFVSQ
AMLSAGKLLTNPHNYNHNKGLEIKRQFEQEPVSLARYNLQDCLLVERIFAKAQLTEYAIQRARLTGLALDRRGASVAAFT
NLYLPLLHRSGYIAPNIGDIEAQHSPGGFVMDSIPGLYDWVLVLDFKSLYPSIIRSFKIDPMGMIEGLKENEKNAIPGFR
GARFSRNKHHLPDILDKLTAARESAKKENNQPFQHAIKIIMNSMYGVLGSAGCRFHDTRLASSITLRGHQIMLETRDFIE
QQGEQVVYGDTDSTFVWLKHCTNAIDAQARGKVLEKRINQYWSNKLNLEFQLDCFLEIEFETCFRKFFMPTLRGSETGSK
KRYAGLKVTNDGELMLFKGLETVRSDWTELAQDFQKKLYAKVFANEPIDSLVIDTVELLNKGELDQQLIYHKRLGRPLNA
YLKNVPPQVRAARLADQINANLGRPLQYQRSGRIAYLITVNGPEPADYRQSCIDYQHYIDKQLKPIAEAILPLLSKNFDD
MISDQMRLF
>Mature_808_residues
SGSQRHQIAGLILTRRQHETPQGVELELWLATKEGPCRVFLPAQRYVFLIHQQQLVKAQALWSAVHLTPNEIRPLSLTSF
NGLSVSAIYCLNNKMFRQLQDILTTASIPIFEADIKVCDRYLMERFIYGTVSVQGECHWQGHYWHCRAAKISPATVTSKL
KQVSLDIECSPLGELYSVGLSYGNTDSDKGSALLDSDCCATVLMIGEHEPCDDINIQWVANEQALLCALEAWFQWHDPDA
VIGWAVTNFDLRLLVKRADAHNMPLRLGRDGSALRWLPHRQAPDQGTVILNGRVVLEGIDQLKNAGWMFESFSLEFVSQA
MLSAGKLLTNPHNYNHNKGLEIKRQFEQEPVSLARYNLQDCLLVERIFAKAQLTEYAIQRARLTGLALDRRGASVAAFTN
LYLPLLHRSGYIAPNIGDIEAQHSPGGFVMDSIPGLYDWVLVLDFKSLYPSIIRSFKIDPMGMIEGLKENEKNAIPGFRG
ARFSRNKHHLPDILDKLTAARESAKKENNQPFQHAIKIIMNSMYGVLGSAGCRFHDTRLASSITLRGHQIMLETRDFIEQ
QGEQVVYGDTDSTFVWLKHCTNAIDAQARGKVLEKRINQYWSNKLNLEFQLDCFLEIEFETCFRKFFMPTLRGSETGSKK
RYAGLKVTNDGELMLFKGLETVRSDWTELAQDFQKKLYAKVFANEPIDSLVIDTVELLNKGELDQQLIYHKRLGRPLNAY
LKNVPPQVRAARLADQINANLGRPLQYQRSGRIAYLITVNGPEPADYRQSCIDYQHYIDKQLKPIAEAILPLLSKNFDDM
ISDQMRLF

Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=721, Percent_Identity=25.1040221914008, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI106507301, Length=672, Percent_Identity=23.8095238095238, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1786246, Length=809, Percent_Identity=46.7243510506799, Blast_Score=723, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559488, Length=675, Percent_Identity=26.3703703703704, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565317, Length=638, Percent_Identity=25.8620689655172, Blast_Score=128, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320101, Length=701, Percent_Identity=25.962910128388, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324227, Length=514, Percent_Identity=26.0700389105058, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325090, Length=489, Percent_Identity=25.3578732106339, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24664937, Length=783, Percent_Identity=24.5210727969349, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24648780, Length=650, Percent_Identity=23.0769230769231, Blast_Score=109, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 91881; Mature: 91749

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSQRHQIAGLILTRRQHETPQGVELELWLATKEGPCRVFLPAQRYVFLIHQQQLVKAQ
CCCCCHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCEEEEECCCEEEEEEEHHHHHHHH
ALWSAVHLTPNEIRPLSLTSFNGLSVSAIYCLNNKMFRQLQDILTTASIPIFEADIKVCD
HHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEHHHHHHH
RYLMERFIYGTVSVQGECHWQGHYWHCRAAKISPATVTSKLKQVSLDIECSPLGELYSVG
HHHHHHHHHEEEEECEEEEECCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCHHHHHHH
LSYGNTDSDKGSALLDSDCCATVLMIGEHEPCDDINIQWVANEQALLCALEAWFQWHDPD
CCCCCCCCCCCCEEECCHHHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
AVIGWAVTNFDLRLLVKRADAHNMPLRLGRDGSALRWLPHRQAPDQGTVILNGRVVLEGI
CEEEEEEECCEEEEEEECCCCCCCCEEECCCCCCEEECCCCCCCCCCEEEECCEEEEHHH
DQLKNAGWMFESFSLEFVSQAMLSAGKLLTNPHNYNHNKGLEIKRQFEQEPVSLARYNLQ
HHHHCCCCEEEHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCHH
DCLLVERIFAKAQLTEYAIQRARLTGLALDRRGASVAAFTNLYLPLLHRSGYIAPNIGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
EAQHSPGGFVMDSIPGLYDWVLVLDFKSLYPSIIRSFKIDPMGMIEGLKENEKNAIPGFR
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC
GARFSRNKHHLPDILDKLTAARESAKKENNQPFQHAIKIIMNSMYGVLGSAGCRFHDTRL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
ASSITLRGHQIMLETRDFIEQQGEQVVYGDTDSTFVWLKHCTNAIDAQARGKVLEKRINQ
HHEEEECCCEEEEHHHHHHHHCCCEEEECCCCCCEEEHHHHCHHHCHHHHHHHHHHHHHH
YWSNKLNLEFQLDCFLEIEFETCFRKFFMPTLRGSETGSKKRYAGLKVTNDGELMLFKGL
HHCCCCCEEEEEEEEEEEEHHHHHHHHHCHHCCCCCCCCCCCCCCCEECCCCCEEEEECH
ETVRSDWTELAQDFQKKLYAKVFANEPIDSLVIDTVELLNKGELDQQLIYHKRLGRPLNA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
YLKNVPPQVRAARLADQINANLGRPLQYQRSGRIAYLITVNGPEPADYRQSCIDYQHYID
HHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KQLKPIAEAILPLLSKNFDDMISDQMRLF
HHHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SGSQRHQIAGLILTRRQHETPQGVELELWLATKEGPCRVFLPAQRYVFLIHQQQLVKAQ
CCCCHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCEEEEECCCEEEEEEEHHHHHHHH
ALWSAVHLTPNEIRPLSLTSFNGLSVSAIYCLNNKMFRQLQDILTTASIPIFEADIKVCD
HHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEHHHHHHH
RYLMERFIYGTVSVQGECHWQGHYWHCRAAKISPATVTSKLKQVSLDIECSPLGELYSVG
HHHHHHHHHEEEEECEEEEECCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCHHHHHHH
LSYGNTDSDKGSALLDSDCCATVLMIGEHEPCDDINIQWVANEQALLCALEAWFQWHDPD
CCCCCCCCCCCCEEECCHHHHHHHEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCC
AVIGWAVTNFDLRLLVKRADAHNMPLRLGRDGSALRWLPHRQAPDQGTVILNGRVVLEGI
CEEEEEEECCEEEEEEECCCCCCCCEEECCCCCCEEECCCCCCCCCCEEEECCEEEEHHH
DQLKNAGWMFESFSLEFVSQAMLSAGKLLTNPHNYNHNKGLEIKRQFEQEPVSLARYNLQ
HHHHCCCCEEEHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCHH
DCLLVERIFAKAQLTEYAIQRARLTGLALDRRGASVAAFTNLYLPLLHRSGYIAPNIGDI
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
EAQHSPGGFVMDSIPGLYDWVLVLDFKSLYPSIIRSFKIDPMGMIEGLKENEKNAIPGFR
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCC
GARFSRNKHHLPDILDKLTAARESAKKENNQPFQHAIKIIMNSMYGVLGSAGCRFHDTRL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHH
ASSITLRGHQIMLETRDFIEQQGEQVVYGDTDSTFVWLKHCTNAIDAQARGKVLEKRINQ
HHEEEECCCEEEEHHHHHHHHCCCEEEECCCCCCEEEHHHHCHHHCHHHHHHHHHHHHHH
YWSNKLNLEFQLDCFLEIEFETCFRKFFMPTLRGSETGSKKRYAGLKVTNDGELMLFKGL
HHCCCCCEEEEEEEEEEEEHHHHHHHHHCHHCCCCCCCCCCCCCCCEECCCCCEEEEECH
ETVRSDWTELAQDFQKKLYAKVFANEPIDSLVIDTVELLNKGELDQQLIYHKRLGRPLNA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
YLKNVPPQVRAARLADQINANLGRPLQYQRSGRIAYLITVNGPEPADYRQSCIDYQHYID
HHHCCCHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KQLKPIAEAILPLLSKNFDDMISDQMRLF
HHHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]