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The map label for this gene is slyD [H]

Identifier: 119945552

GI number: 119945552

Start: 2255254

End: 2255733

Strand: Direct

Name: slyD [H]

Synonym: Ping_1856

Alternate gene names: 119945552

Gene position: 2255254-2255733 (Clockwise)

Preceding gene: 119945551

Following gene: 119945553

Centisome position: 49.46

GC content: 42.92

Gene sequence:

>480_bases
ATGTTAATTAACAAAAATTCAGTCGTTGAATTCCATTACACATTAAGAGATACAGATAAAGAACTTGAAAACAGTTATGG
CGGTGAGCCATTAATTTATTTACATGGTTTTAAGGGGTTATTTGAAACACTGGAAAATGCCCTGGTCGGTAAAACAGTCG
GCGACAAATTAGAGGTGACATTAACACCTGAGCAAAGTTATGGTCAACGTAGAGAAGGCGCTTTACAACGCATCCCCATT
AAACATCTGCAGGGGGCAAAAGTCTGGAAGCCGGGTATGACAGCGGTTGTTGAATCAAATCAGGGGCGTGAGCAGGTGAC
CATAGTAAAAGTGGGGCGTTTTAATGCCGATTGTGATTTAAATCATCCTCTTGCGGGTAAAACTTTAACCTTTGCGATTG
AAGTCGTTGCGCTGCGTGAGGCCACAGAGGAAGAAATAACGCATGGCCATGTGCATAATAAAGGCGGATGCGGCCACTAA

Upstream 100 bases:

>100_bases
GGTGAGCATTGTCATGACGATGCTCATACTCATTGCCATGATCATGAGCATTAAGACTATTGGCCATACCCTAAATTATT
TTTATAAATGAGATTTATAT

Downstream 100 bases:

>100_bases
TCATTAATTGATTTTTAAAAAGGCGCAGAGTGCGCCTTTACCCTTATATTTTTTATCTCTTCTTTTTCAGATTCCATTAA
TCAGCAATAATTGAGGTCAG

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MLINKNSVVEFHYTLRDTDKELENSYGGEPLIYLHGFKGLFETLENALVGKTVGDKLEVTLTPEQSYGQRREGALQRIPI
KHLQGAKVWKPGMTAVVESNQGREQVTIVKVGRFNADCDLNHPLAGKTLTFAIEVVALREATEEEITHGHVHNKGGCGH

Sequences:

>Translated_159_residues
MLINKNSVVEFHYTLRDTDKELENSYGGEPLIYLHGFKGLFETLENALVGKTVGDKLEVTLTPEQSYGQRREGALQRIPI
KHLQGAKVWKPGMTAVVESNQGREQVTIVKVGRFNADCDLNHPLAGKTLTFAIEVVALREATEEEITHGHVHNKGGCGH
>Mature_159_residues
MLINKNSVVEFHYTLRDTDKELENSYGGEPLIYLHGFKGLFETLENALVGKTVGDKLEVTLTPEQSYGQRREGALQRIPI
KHLQGAKVWKPGMTAVVESNQGREQVTIVKVGRFNADCDLNHPLAGKTLTFAIEVVALREATEEEITHGHVHNKGGCGH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=41.2162162162162, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1786211, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17632; Mature: 17632

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINKNSVVEFHYTLRDTDKELENSYGGEPLIYLHGFKGLFETLENALVGKTVGDKLEVT
CEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEE
LTPEQSYGQRREGALQRIPIKHLQGAKVWKPGMTAVVESNQGREQVTIVKVGRFNADCDL
ECCCHHCCCHHCCHHHCCCHHHCCCCCEECCCCEEEEECCCCCCEEEEEEEECCCCCCCC
NHPLAGKTLTFAIEVVALREATEEEITHGHVHNKGGCGH
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLINKNSVVEFHYTLRDTDKELENSYGGEPLIYLHGFKGLFETLENALVGKTVGDKLEVT
CEECCCCEEEEEEEECCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEE
LTPEQSYGQRREGALQRIPIKHLQGAKVWKPGMTAVVESNQGREQVTIVKVGRFNADCDL
ECCCHHCCCHHCCHHHCCCHHHCCCCCEECCCCEEEEECCCCCCEEEEEEEECCCCCCCC
NHPLAGKTLTFAIEVVALREATEEEITHGHVHNKGGCGH
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]