The gene/protein map for NC_008709 is currently unavailable.
Definition Psychromonas ingrahamii 37, complete genome.
Accession NC_008709
Length 4,559,598

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The map label for this gene is serS

Identifier: 119945378

GI number: 119945378

Start: 2023037

End: 2024323

Strand: Direct

Name: serS

Synonym: Ping_1666

Alternate gene names: 119945378

Gene position: 2023037-2024323 (Clockwise)

Preceding gene: 119945377

Following gene: 119945381

Centisome position: 44.37

GC content: 42.19

Gene sequence:

>1287_bases
ATGTTAGATCCAAAATTTTTACGTAACGATATAGAACAAACTGCATTACGATTAGCTTCTCGTGGATATACTTTAGATGT
TGAATTATTAAATCAACTGGAAGAAAAAAGGAAAATTCTACAGATTACCACTGAAACCTTACAAGCCGAGCGTAATAGCC
GTTCTAAAGAGGTTGGCCAAGCGGCAAAACGGGGTGAAGATATTACCCCGCTGCGCACTGAAATGGGCTTATTAGGCGAA
AGATTAGACAGTGCCAAAGAAGATTTTGCACTGTTAGCAGAGCAGATTAAAAGTTTGGCATACAGTATGCCTAATTTACC
GCATGAATCAGCACCTCTTGGTAAAGATGAAAGTGAAAATGTAGAAATATTAAAATGGGGTGAGCCGAAGAAGTTTGATT
TTGAAGTCAAAGATCATGTTGATTTGGGCGAAGCCTTAGACGGTTTAGATTTTAAATCGGCCGTTAAAATCAGCGGCTCA
CGTTTTATTGTTATGCGCGGTAAAATCGCTAAATTACACCGCGCTTTAGCGCAGTATATGCTAGATCTTCACACCGATCA
TCATGGTTATACAGAGATGTATGTCCCTTATCTGGTCAATGCTGATAGTTTATACGGTACCGGGCAGCTGCCTAAATTTG
GTGATGACTTGTTTAATACTAAGCCGGCAACAGAAGAAGGCATTGGTATGTCACTTATCCCAACGGCTGAAGTTCCGCTG
ACTAATATGAGCCGGGATATGATCTATGATGAATCTGATTTGCCGCTTAAATTAACGGCCCATACCCCTTGTTTCAGAAG
TGAAGCGGGATCCTATGGTCGTGATACGCGTGGTTTAATTCGTCAGCATCAGTTTGATAAAGTTGAAATGGTGCAGTTTG
TGCATCCTGAAAAAAGTTTTGAAGCATTGGAAGAGTTAACCGGGCATGCCGAACAGGTATTAAAAAATCTGCAATTACCT
TACCGTAAAGTGGTTTTATGTACTGGTGATATGGGCTTTGGCGCAACTAAAACCTATGACTTGGAGGTGTGGTTGCCTGC
ACAAGATCAATATCGAGAAATTTCATCTTGCTCAAATATTGGTGATTTTCAGGCGCGCCGTTTGCAGGCGCGTTTCCGCC
CGACAGGTGCTAAAAAGCCGGAGTTATTACACACTCTAAACGGCTCTGGGTTAGCAGTGGGTCGTACTTTGGTTGCTGTG
CTAGAAAACTACCAACTTGAGGATGGCAGTATTGAAATCCCGCAGGTGTTACAACAATATATGGGCGGCTTGACACATAT
CGGCTAG

Upstream 100 bases:

>100_bases
AGTTATTTAAAGCGATGCTAAATATCGCATTAAATGTTGTGGTCTGCCTTTTCGCCGCATATGTTGGCACATTATTAGTC
TTTAAAAGTTAGGAAGAAGC

Downstream 100 bases:

>100_bases
ATATTCTCAAAAATTCAACCTTTGAACAGGTGCAGGGCACATTCTCGTCATCTTTAGCGGCGAAGCCCTGCAAAATACCA
AATCCATTAAATTCATGCCC

Product: seryl-tRNA synthetase

Products: NA

Alternate protein names: Serine--tRNA ligase; SerRS; Seryl-tRNA(Ser/Sec) synthetase

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MLDPKFLRNDIEQTALRLASRGYTLDVELLNQLEEKRKILQITTETLQAERNSRSKEVGQAAKRGEDITPLRTEMGLLGE
RLDSAKEDFALLAEQIKSLAYSMPNLPHESAPLGKDESENVEILKWGEPKKFDFEVKDHVDLGEALDGLDFKSAVKISGS
RFIVMRGKIAKLHRALAQYMLDLHTDHHGYTEMYVPYLVNADSLYGTGQLPKFGDDLFNTKPATEEGIGMSLIPTAEVPL
TNMSRDMIYDESDLPLKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQFVHPEKSFEALEELTGHAEQVLKNLQLP
YRKVVLCTGDMGFGATKTYDLEVWLPAQDQYREISSCSNIGDFQARRLQARFRPTGAKKPELLHTLNGSGLAVGRTLVAV
LENYQLEDGSIEIPQVLQQYMGGLTHIG

Sequences:

>Translated_428_residues
MLDPKFLRNDIEQTALRLASRGYTLDVELLNQLEEKRKILQITTETLQAERNSRSKEVGQAAKRGEDITPLRTEMGLLGE
RLDSAKEDFALLAEQIKSLAYSMPNLPHESAPLGKDESENVEILKWGEPKKFDFEVKDHVDLGEALDGLDFKSAVKISGS
RFIVMRGKIAKLHRALAQYMLDLHTDHHGYTEMYVPYLVNADSLYGTGQLPKFGDDLFNTKPATEEGIGMSLIPTAEVPL
TNMSRDMIYDESDLPLKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQFVHPEKSFEALEELTGHAEQVLKNLQLP
YRKVVLCTGDMGFGATKTYDLEVWLPAQDQYREISSCSNIGDFQARRLQARFRPTGAKKPELLHTLNGSGLAVGRTLVAV
LENYQLEDGSIEIPQVLQQYMGGLTHIG
>Mature_428_residues
MLDPKFLRNDIEQTALRLASRGYTLDVELLNQLEEKRKILQITTETLQAERNSRSKEVGQAAKRGEDITPLRTEMGLLGE
RLDSAKEDFALLAEQIKSLAYSMPNLPHESAPLGKDESENVEILKWGEPKKFDFEVKDHVDLGEALDGLDFKSAVKISGS
RFIVMRGKIAKLHRALAQYMLDLHTDHHGYTEMYVPYLVNADSLYGTGQLPKFGDDLFNTKPATEEGIGMSLIPTAEVPL
TNMSRDMIYDESDLPLKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQFVHPEKSFEALEELTGHAEQVLKNLQLP
YRKVVLCTGDMGFGATKTYDLEVWLPAQDQYREISSCSNIGDFQARRLQARFRPTGAKKPELLHTLNGSGLAVGRTLVAV
LENYQLEDGSIEIPQVLQQYMGGLTHIG

Specific function: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

COG id: COG0172

COG function: function code J; Seryl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily

Homologues:

Organism=Homo sapiens, GI16306548, Length=356, Percent_Identity=36.2359550561798, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI225579074, Length=405, Percent_Identity=32.3456790123457, Blast_Score=185, Evalue=7e-47,
Organism=Homo sapiens, GI8923421, Length=404, Percent_Identity=32.9207920792079, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1787120, Length=430, Percent_Identity=67.2093023255814, Blast_Score=618, Evalue=1e-178,
Organism=Caenorhabditis elegans, GI17539260, Length=330, Percent_Identity=34.8484848484849, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17542084, Length=338, Percent_Identity=26.6272189349112, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320226, Length=430, Percent_Identity=30, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321799, Length=375, Percent_Identity=30.1333333333333, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24581334, Length=343, Percent_Identity=37.6093294460641, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI17737985, Length=329, Percent_Identity=31.6109422492401, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYS_PSYIN (A1SVE4)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943058.1
- ProteinModelPortal:   A1SVE4
- SMR:   A1SVE4
- STRING:   A1SVE4
- GeneID:   4626915
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1666
- eggNOG:   COG0172
- HOGENOM:   HBG629391
- OMA:   FQARRIR
- PhylomeDB:   A1SVE4
- BioCyc:   PING357804:PING_1666-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00176
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR002317
- InterPro:   IPR015866
- InterPro:   IPR010978
- Gene3D:   G3DSA:1.10.287.40
- PANTHER:   PTHR11778
- PIRSF:   PIRSF001529
- PRINTS:   PR00981
- TIGRFAMs:   TIGR00414

Pfam domain/function: PF02403 Seryl_tRNA_N; PF00587 tRNA-synt_2b; SSF46589 tRNA_binding_arm

EC number: =6.1.1.11

Molecular weight: Translated: 48100; Mature: 48100

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: BINDING 289-289 BINDING 389-389

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLDPKFLRNDIEQTALRLASRGYTLDVELLNQLEEKRKILQITTETLQAERNSRSKEVGQ
CCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AAKRGEDITPLRTEMGLLGERLDSAKEDFALLAEQIKSLAYSMPNLPHESAPLGKDESEN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VEILKWGEPKKFDFEVKDHVDLGEALDGLDFKSAVKISGSRFIVMRGKIAKLHRALAQYM
EEEEECCCCCCCCCCHHCCCCHHHHHCCCCCHHHEEECCCEEEEECCHHHHHHHHHHHHH
LDLHTDHHGYTEMYVPYLVNADSLYGTGQLPKFGDDLFNTKPATEEGIGMSLIPTAEVPL
HHHHCCCCCCCEEEECEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCC
TNMSRDMIYDESDLPLKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQFVHPEKSF
CCCCHHHEECCCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHH
EALEELTGHAEQVLKNLQLPYRKVVLCTGDMGFGATKTYDLEVWLPAQDQYREISSCSNI
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHCCC
GDFQARRLQARFRPTGAKKPELLHTLNGSGLAVGRTLVAVLENYQLEDGSIEIPQVLQQY
CHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MGGLTHIG
HHHHCCCC
>Mature Secondary Structure
MLDPKFLRNDIEQTALRLASRGYTLDVELLNQLEEKRKILQITTETLQAERNSRSKEVGQ
CCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AAKRGEDITPLRTEMGLLGERLDSAKEDFALLAEQIKSLAYSMPNLPHESAPLGKDESEN
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VEILKWGEPKKFDFEVKDHVDLGEALDGLDFKSAVKISGSRFIVMRGKIAKLHRALAQYM
EEEEECCCCCCCCCCHHCCCCHHHHHCCCCCHHHEEECCCEEEEECCHHHHHHHHHHHHH
LDLHTDHHGYTEMYVPYLVNADSLYGTGQLPKFGDDLFNTKPATEEGIGMSLIPTAEVPL
HHHHCCCCCCCEEEECEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEECCCCCCCC
TNMSRDMIYDESDLPLKLTAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQFVHPEKSF
CCCCHHHEECCCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCHHH
EALEELTGHAEQVLKNLQLPYRKVVLCTGDMGFGATKTYDLEVWLPAQDQYREISSCSNI
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHHCCC
GDFQARRLQARFRPTGAKKPELLHTLNGSGLAVGRTLVAVLENYQLEDGSIEIPQVLQQY
CHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
MGGLTHIG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA