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The map label for this gene is fadR [H]

Identifier: 119945373

GI number: 119945373

Start: 2017293

End: 2018003

Strand: Direct

Name: fadR [H]

Synonym: Ping_1661

Alternate gene names: 119945373

Gene position: 2017293-2018003 (Clockwise)

Preceding gene: 119945371

Following gene: 119945374

Centisome position: 44.24

GC content: 38.68

Gene sequence:

>711_bases
ATGATAAAAAACGTAAAAGGGCCTGCAGACATAGCTGAACAGTATTTGATAGAGTCTATTTGGAATGGCACTATTGCAAT
ACATTCAGCATTGCCCGCTGAACGAGTGCTTGCTGATAAAATAGGAGTGACGCGCACTACTCTGCGTGAGGTTTTACAGC
GTATGTCAAAGGATGGTTGGATTACAATTTGCCATGGTAAGTCAACGAAAGTAAATGATTTTTGGGAAACCTCAAGTTTA
AATGTGTTAAGTACTATTACCCGCCTTGATATTGAGAGGCGGGCAGATTATATTGACCAACTGATGTCAGTACGTACTAA
TGTTAGCGCCATTATTTTACGCATGGCTGCAAAGCATAATACAAAAAGTGTGCTTTCTTTTTTAGATAAAGTACCTTCAA
TTGATGCCAGCAGTGAAGAATTTACTGAATTTGATTACCGTTTTTATCACCATGTCGCTGTTTCCTCCAATAATATGATT
TATGTTTTGATTCTTAATGGGTTACAGGACTTGTATCGCCGGGTTGGCTATTTTTATTTTTCAAATACAGAGGCTAAATC
TATTGCTCTGGCTTTTTACGCTGACATTAAAATTGTATTAGAGAAAGGGGAAATACATCAGATCATGCAGGTTGTTCGCG
ATTCGGCTTTCGCCAGTGGAAAAATTTGGCTGCATTTACGTCACCAGCTTCCCGATGACTTTCTGGATTAA

Upstream 100 bases:

>100_bases
TACATTTGATTGTTGATGCTTGATTTACAAAGATAAACGACCTGTTTTGTCTATTAACCTCTGTGTTACTATAGAAAGAT
AAAAGTAAGGGGGATTTTAA

Downstream 100 bases:

>100_bases
ATAAACTAAATTAATGTTTCACTACTTTTTTATAACAGGATAACTCTTTTGTCGAAAAACAACTTTCTTAACCGGCTCTC
CGGTGCACAAAAATTATTAG

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MIKNVKGPADIAEQYLIESIWNGTIAIHSALPAERVLADKIGVTRTTLREVLQRMSKDGWITICHGKSTKVNDFWETSSL
NVLSTITRLDIERRADYIDQLMSVRTNVSAIILRMAAKHNTKSVLSFLDKVPSIDASSEEFTEFDYRFYHHVAVSSNNMI
YVLILNGLQDLYRRVGYFYFSNTEAKSIALAFYADIKIVLEKGEIHQIMQVVRDSAFASGKIWLHLRHQLPDDFLD

Sequences:

>Translated_236_residues
MIKNVKGPADIAEQYLIESIWNGTIAIHSALPAERVLADKIGVTRTTLREVLQRMSKDGWITICHGKSTKVNDFWETSSL
NVLSTITRLDIERRADYIDQLMSVRTNVSAIILRMAAKHNTKSVLSFLDKVPSIDASSEEFTEFDYRFYHHVAVSSNNMI
YVLILNGLQDLYRRVGYFYFSNTEAKSIALAFYADIKIVLEKGEIHQIMQVVRDSAFASGKIWLHLRHQLPDDFLD
>Mature_236_residues
MIKNVKGPADIAEQYLIESIWNGTIAIHSALPAERVLADKIGVTRTTLREVLQRMSKDGWITICHGKSTKVNDFWETSSL
NVLSTITRLDIERRADYIDQLMSVRTNVSAIILRMAAKHNTKSVLSFLDKVPSIDASSEEFTEFDYRFYHHVAVSSNNMI
YVLILNGLQDLYRRVGYFYFSNTEAKSIALAFYADIKIVLEKGEIHQIMQVVRDSAFASGKIWLHLRHQLPDDFLD

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=234, Percent_Identity=46.5811965811966, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26987; Mature: 26987

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNVKGPADIAEQYLIESIWNGTIAIHSALPAERVLADKIGVTRTTLREVLQRMSKDGW
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCE
ITICHGKSTKVNDFWETSSLNVLSTITRLDIERRADYIDQLMSVRTNVSAIILRMAAKHN
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKSVLSFLDKVPSIDASSEEFTEFDYRFYHHVAVSSNNMIYVLILNGLQDLYRRVGYFYF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHHCEEEE
SNTEAKSIALAFYADIKIVLEKGEIHQIMQVVRDSAFASGKIWLHLRHQLPDDFLD
CCCCHHHEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHCC
>Mature Secondary Structure
MIKNVKGPADIAEQYLIESIWNGTIAIHSALPAERVLADKIGVTRTTLREVLQRMSKDGW
CCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCE
ITICHGKSTKVNDFWETSSLNVLSTITRLDIERRADYIDQLMSVRTNVSAIILRMAAKHN
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKSVLSFLDKVPSIDASSEEFTEFDYRFYHHVAVSSNNMIYVLILNGLQDLYRRVGYFYF
HHHHHHHHHHCCCCCCCCHHHHHHHHHHEEEEEECCCCEEEEEEHHHHHHHHHHHCEEEE
SNTEAKSIALAFYADIKIVLEKGEIHQIMQVVRDSAFASGKIWLHLRHQLPDDFLD
CCCCHHHEEEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA