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The map label for this gene is putA [H]

Identifier: 119945270

GI number: 119945270

Start: 1888116

End: 1891946

Strand: Reverse

Name: putA [H]

Synonym: Ping_1543

Alternate gene names: 119945270

Gene position: 1891946-1888116 (Counterclockwise)

Preceding gene: 119945278

Following gene: 119945268

Centisome position: 41.49

GC content: 40.93

Gene sequence:

>3831_bases
ATGCTTTTTAATAATTCAAACATCACAGCGTCCCCTATTCGTCAAAAAATTCGCGAGTTCTATCGTATTGATGAAAGTAT
TGCGGTAGAGCATATTTTACCCTTGGCAGAAGTTAACGATAATGCAGCAAGCAGAGCGTGGGAAAAAGCCCGTAAAATGT
CTATGAAAATACGTAAAGATGAATCGGGAAACGGTGCGGTAGATGCCTTACTGGCAGAATACACATTATCAAGTGAAGAA
GGTGTGGTGTTGATGTGTTTAGCCGAAGCCTTATTACGTGTGCCAGATAAGCATACCCAAGATGCCCTCATTAGTGACAA
AATATCTAAAGGGCAGTGGGACAGTCATCTAGGCAGCAGTGATTCACTGTTCGTTAATGCCTCATCTTGGGGGTTATTAG
TGACCGGAAAGATGGTTGACTATGCTGATGAACGCGAAAAAGATAGCTTTGATTTATTGAAGAAGGTTATTGGTCGATTA
GGTGAGCCTGTCATTCGCAAGTCAATGAACTACGCCATGCAAATTATGGGTGAGCAGTTTGTTATGGGCGAAACTATTCA
AGATGCTACTGATCATGCTGCCAAGAAAGCGCGGCAAGGCTTCGTCTATTCTTACGACATGCTAGGTGAAGGTGCGCGAA
CCATGAGTGACGCTGAAAAGTATTTTAAAGCTTATCAAGTTGCTATAGATGCTATTGGCGCAGTTGCTCGTGCGTCGGGT
AAGAACGACCCTCGCAAAGTGCCTGGTATTTCAGTTAAGCTTACTGCGATTCATCCTCGTTACGAATTTGCACAAAAAGA
ACGGGTAATGGCTGAAGTTGCTCCCAAACTTAAAGCACTTTGTTTGCAAGCCAAAAGCTACAATATTGGTTTAACTGTTG
ATGCGGAAGAGTCTGAGCGATTAGATATCTCCCTTGATGTTATTGAGGCGGTATTTAGTGATGATGAGTTAGCAGGTTGG
AATGGCTTTTCGATGGCCCTGCAAGCTTATCAAAAACGCGCTATTTTTATAGTTGACTGGTTACGTGAACTAACCATCCG
TGTTGACCGAAAAATGATGGTGCGCTTGGTAAAAGGTGCTTATTGGGATACTCAGATTAAAAACAGCCAAAAAGGGGGTT
ATCAGCATTTTCCGCTATTCACTCGCAAGGCTTCGACTGATGTATCTTACATCGCCTGTGCGAAAAAATTATTAGAATAT
AGAGATACCATCTTTCCACAGTTTGCTACGCATAATGCTTACACTGTCGCGACTATTCTTGAGCTGGCGGGCAATGACAA
AACAAGTTTTGAATTCCAATGTCTATATGGCATGGGTGGCTCGTTATATGATCAAGTTGTTACAAATGAAAATGTTCAAT
GTCGCATCTACGCACCGGTTGGTCCTCATGAAGATCTACTCGCCTATTTAGTTCGTCGTTTGTTAGAAAATGGCGCTAAC
TCTTCTTTTGTTAACGCCATTATTGATGACTCACAACCGATCGAATCTTTGCTTCGCAATCCCGTTGAAAAAATGCATAG
CTTAAAAGACAAATATAACGGCCAGATAATCAAACCCATCGCGTTATACCATGATCAAAAAGGTGTCGGTCGAGATAATT
CCAAGGGCCTAGATTTAACAGATATCAATACAGTAACCCCTTTAAAAACATCACTGGATAACTGGCTTGTGAATAACTTG
TTCTCTGAAGATGATGTGCCAGAAGGTTCTATCGCTATTAGAAACCCAGCAAAGCAGAGTGAAATTATTGGTTTTCAACG
ACATCACAGCAAGGATGAAATGCTCGCGATGGTCGAAACAGCTCACAATGCATTTGCTTCATGGTCACAAACGTCTGTAT
CTGAACGTGCGGACTTATTATGCCGTGTTGCCGATGTTCTTGAACATCATATGGATGAGTTTATTGCCTTATGCATTAAG
GAAGCAGGGAAAACGACACAAGATGGTATTGATGAAGTCAAAGAGGCAGTTGATTTTTGTCGCTATTATGCACAACAAGC
GATTGAACTTGCAGAAGATGATCGTATAGAAGCCCGTGGTGTGGTGTTATGTATCAGCCCCTGGAACTTCCCGTTAGCTA
TATTTGTAGGGCAAGTGACTGCTGCCATTGCTACTGGTAATACAGTGTTAGCTAAACCAGCCCAGCAAACAAGTTTAATT
GCATTGCGCGCTATTGAACTAATGACATCGGTTGGATTACCCCATGGCGTTGTACAAGCCGTTATTGCAAAGGGTAGTGA
TGTGGGTAAAGTTATTATTCCTAATGCACGTATTCAAGCGGTTATTTTTACTGGTTCTATTAAAACAGCGACTATAATTT
CGCAAACATTGGCTGATAGAGGTGGCGATCAAGTGCCGTTTATTGCTGAGACGGGTGGTCAAAACTGTATGTTAGTTGAC
TCTACCGCCCTACCTGAACAAGTCGTTGATGATGTTATTTCTTCAGGATTTCAATCTGCAGGTCAACGTTGTTCTGCACT
TCGAGTGTTATTTTTACAAGAAGATATTGCTGATAATGTTATTACAATGCTTAAAGGCGCATTAGCAGAATTGCATGTGG
GTAACCCAGAAAAACTGAGTACTGACGTAGGTCCTGTTATTGATCAAAAAGCGCTAGATTCACTCAATGCTCACAGTGAC
TATATGAAAACCCATGGTCAACTATTATATCAATGCGATATTTCTGATGAGATAACAAATGAAATAGCAGATAACGAACA
TTTCTTTTTTGCGCCACGACTTTATGAAATAGAGAATATTAGCGCGCTGAAGGAGGAAGTATTTGGCCCTTGTGTTCATA
TTGTTCGCTTTAAAGGCGATGAAATAGAAAAAGTCGTTGATGATATTAACGACACAGGTTTTGGCTTAACGATGGGTATC
CATACCCGTATTGAACAGCGAGCCTTAAAGTTGGCGAAGCTATCACGAGCAGGTAATGTGTATATAAATCGCAATATAAT
TGGCGCTATTGTGGGTGTGCAACCTTTTGGTGGTCGTGGTCTTTCAGGTACAGGGCCAAAAGCAGGTGGCCCATATTATT
TAACGCGTTTAGTTAAAGAAATAACAACGCCCGCTGCCAAGAAACTTAATTTAATACCACAGCAAGCAGAAGCATCAAAC
AGCGATACGGATGCGCAAGCAGTATTATTTATGGACAAAGCGAGGACAGCAGAAAAAATCTGGCGCTTGACCGAGTTAAA
TACCCGTATATCTTGTGTTAGCGAAGTGTTAGCAAAAATAGCTCATATCGATATCATTACTAATTTAGCAGACGATTTAA
CTAATACTTTAAAAGCGGCGCGCTCACAATTAATTGATATTGAAAAACACTTGAAAGAACCAACCGTTTTACCAGGTCCA
ACAGGTGAGTCTAATATTCTATATTTAGAAAATCGTGGCAACATAATCTGTTTTGCTGACGAGAATGTTAGTTTTCACTT
TTGGTTGCTTTCTGTCGTAACGGCTTTGGCAACGGGTAATACCGTGATCTCCGTTGTCTCTGACTTGTTTTATGATCAAG
CAATCGCTTTTAGAGATGAACTTATTGCAACAGGGGAAGATGAGAATATTTTTCAAATTGCCCGGTTATGCCATTTAACA
ACGTTGCTGGCACAGCCTGGATTATCAGGTGTTGTTGTTGATAGTCATTGCGACCGTGAACATTATATCAGTGAGAAATT
AGCAGAACGTCAAGGTGCAATTTTACCGGTGATCAGTTCAAAATATGTTGATAATTTAATGCAGCGATTATTAACAGAAA
AAGCTGTCAGTATTAATACCACCGCGACCGGTGGTAATACGTCACTCATGACCTTAGATGAAGAAGATTAA

Upstream 100 bases:

>100_bases
ACACCAACTGAATTTTACATTCAATCGAAGCAGTCAATTAAATTGTAATTAACTTATGTTATTGTAATACATTATTTAAA
AAAATTTTGAGGTGAAGCAC

Downstream 100 bases:

>100_bases
CGATCAAGGAGCGGTTCGTTTTGGATACTAACATTCGAAGCGAAACCCTTGACGGAGGATCCATCATCTTAATGTCTTAT
TGACAAAAAAAATCAGCAAC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1276; Mature: 1276

Protein sequence:

>1276_residues
MLFNNSNITASPIRQKIREFYRIDESIAVEHILPLAEVNDNAASRAWEKARKMSMKIRKDESGNGAVDALLAEYTLSSEE
GVVLMCLAEALLRVPDKHTQDALISDKISKGQWDSHLGSSDSLFVNASSWGLLVTGKMVDYADEREKDSFDLLKKVIGRL
GEPVIRKSMNYAMQIMGEQFVMGETIQDATDHAAKKARQGFVYSYDMLGEGARTMSDAEKYFKAYQVAIDAIGAVARASG
KNDPRKVPGISVKLTAIHPRYEFAQKERVMAEVAPKLKALCLQAKSYNIGLTVDAEESERLDISLDVIEAVFSDDELAGW
NGFSMALQAYQKRAIFIVDWLRELTIRVDRKMMVRLVKGAYWDTQIKNSQKGGYQHFPLFTRKASTDVSYIACAKKLLEY
RDTIFPQFATHNAYTVATILELAGNDKTSFEFQCLYGMGGSLYDQVVTNENVQCRIYAPVGPHEDLLAYLVRRLLENGAN
SSFVNAIIDDSQPIESLLRNPVEKMHSLKDKYNGQIIKPIALYHDQKGVGRDNSKGLDLTDINTVTPLKTSLDNWLVNNL
FSEDDVPEGSIAIRNPAKQSEIIGFQRHHSKDEMLAMVETAHNAFASWSQTSVSERADLLCRVADVLEHHMDEFIALCIK
EAGKTTQDGIDEVKEAVDFCRYYAQQAIELAEDDRIEARGVVLCISPWNFPLAIFVGQVTAAIATGNTVLAKPAQQTSLI
ALRAIELMTSVGLPHGVVQAVIAKGSDVGKVIIPNARIQAVIFTGSIKTATIISQTLADRGGDQVPFIAETGGQNCMLVD
STALPEQVVDDVISSGFQSAGQRCSALRVLFLQEDIADNVITMLKGALAELHVGNPEKLSTDVGPVIDQKALDSLNAHSD
YMKTHGQLLYQCDISDEITNEIADNEHFFFAPRLYEIENISALKEEVFGPCVHIVRFKGDEIEKVVDDINDTGFGLTMGI
HTRIEQRALKLAKLSRAGNVYINRNIIGAIVGVQPFGGRGLSGTGPKAGGPYYLTRLVKEITTPAAKKLNLIPQQAEASN
SDTDAQAVLFMDKARTAEKIWRLTELNTRISCVSEVLAKIAHIDIITNLADDLTNTLKAARSQLIDIEKHLKEPTVLPGP
TGESNILYLENRGNIICFADENVSFHFWLLSVVTALATGNTVISVVSDLFYDQAIAFRDELIATGEDENIFQIARLCHLT
TLLAQPGLSGVVVDSHCDREHYISEKLAERQGAILPVISSKYVDNLMQRLLTEKAVSINTTATGGNTSLMTLDEED

Sequences:

>Translated_1276_residues
MLFNNSNITASPIRQKIREFYRIDESIAVEHILPLAEVNDNAASRAWEKARKMSMKIRKDESGNGAVDALLAEYTLSSEE
GVVLMCLAEALLRVPDKHTQDALISDKISKGQWDSHLGSSDSLFVNASSWGLLVTGKMVDYADEREKDSFDLLKKVIGRL
GEPVIRKSMNYAMQIMGEQFVMGETIQDATDHAAKKARQGFVYSYDMLGEGARTMSDAEKYFKAYQVAIDAIGAVARASG
KNDPRKVPGISVKLTAIHPRYEFAQKERVMAEVAPKLKALCLQAKSYNIGLTVDAEESERLDISLDVIEAVFSDDELAGW
NGFSMALQAYQKRAIFIVDWLRELTIRVDRKMMVRLVKGAYWDTQIKNSQKGGYQHFPLFTRKASTDVSYIACAKKLLEY
RDTIFPQFATHNAYTVATILELAGNDKTSFEFQCLYGMGGSLYDQVVTNENVQCRIYAPVGPHEDLLAYLVRRLLENGAN
SSFVNAIIDDSQPIESLLRNPVEKMHSLKDKYNGQIIKPIALYHDQKGVGRDNSKGLDLTDINTVTPLKTSLDNWLVNNL
FSEDDVPEGSIAIRNPAKQSEIIGFQRHHSKDEMLAMVETAHNAFASWSQTSVSERADLLCRVADVLEHHMDEFIALCIK
EAGKTTQDGIDEVKEAVDFCRYYAQQAIELAEDDRIEARGVVLCISPWNFPLAIFVGQVTAAIATGNTVLAKPAQQTSLI
ALRAIELMTSVGLPHGVVQAVIAKGSDVGKVIIPNARIQAVIFTGSIKTATIISQTLADRGGDQVPFIAETGGQNCMLVD
STALPEQVVDDVISSGFQSAGQRCSALRVLFLQEDIADNVITMLKGALAELHVGNPEKLSTDVGPVIDQKALDSLNAHSD
YMKTHGQLLYQCDISDEITNEIADNEHFFFAPRLYEIENISALKEEVFGPCVHIVRFKGDEIEKVVDDINDTGFGLTMGI
HTRIEQRALKLAKLSRAGNVYINRNIIGAIVGVQPFGGRGLSGTGPKAGGPYYLTRLVKEITTPAAKKLNLIPQQAEASN
SDTDAQAVLFMDKARTAEKIWRLTELNTRISCVSEVLAKIAHIDIITNLADDLTNTLKAARSQLIDIEKHLKEPTVLPGP
TGESNILYLENRGNIICFADENVSFHFWLLSVVTALATGNTVISVVSDLFYDQAIAFRDELIATGEDENIFQIARLCHLT
TLLAQPGLSGVVVDSHCDREHYISEKLAERQGAILPVISSKYVDNLMQRLLTEKAVSINTTATGGNTSLMTLDEED
>Mature_1276_residues
MLFNNSNITASPIRQKIREFYRIDESIAVEHILPLAEVNDNAASRAWEKARKMSMKIRKDESGNGAVDALLAEYTLSSEE
GVVLMCLAEALLRVPDKHTQDALISDKISKGQWDSHLGSSDSLFVNASSWGLLVTGKMVDYADEREKDSFDLLKKVIGRL
GEPVIRKSMNYAMQIMGEQFVMGETIQDATDHAAKKARQGFVYSYDMLGEGARTMSDAEKYFKAYQVAIDAIGAVARASG
KNDPRKVPGISVKLTAIHPRYEFAQKERVMAEVAPKLKALCLQAKSYNIGLTVDAEESERLDISLDVIEAVFSDDELAGW
NGFSMALQAYQKRAIFIVDWLRELTIRVDRKMMVRLVKGAYWDTQIKNSQKGGYQHFPLFTRKASTDVSYIACAKKLLEY
RDTIFPQFATHNAYTVATILELAGNDKTSFEFQCLYGMGGSLYDQVVTNENVQCRIYAPVGPHEDLLAYLVRRLLENGAN
SSFVNAIIDDSQPIESLLRNPVEKMHSLKDKYNGQIIKPIALYHDQKGVGRDNSKGLDLTDINTVTPLKTSLDNWLVNNL
FSEDDVPEGSIAIRNPAKQSEIIGFQRHHSKDEMLAMVETAHNAFASWSQTSVSERADLLCRVADVLEHHMDEFIALCIK
EAGKTTQDGIDEVKEAVDFCRYYAQQAIELAEDDRIEARGVVLCISPWNFPLAIFVGQVTAAIATGNTVLAKPAQQTSLI
ALRAIELMTSVGLPHGVVQAVIAKGSDVGKVIIPNARIQAVIFTGSIKTATIISQTLADRGGDQVPFIAETGGQNCMLVD
STALPEQVVDDVISSGFQSAGQRCSALRVLFLQEDIADNVITMLKGALAELHVGNPEKLSTDVGPVIDQKALDSLNAHSD
YMKTHGQLLYQCDISDEITNEIADNEHFFFAPRLYEIENISALKEEVFGPCVHIVRFKGDEIEKVVDDINDTGFGLTMGI
HTRIEQRALKLAKLSRAGNVYINRNIIGAIVGVQPFGGRGLSGTGPKAGGPYYLTRLVKEITTPAAKKLNLIPQQAEASN
SDTDAQAVLFMDKARTAEKIWRLTELNTRISCVSEVLAKIAHIDIITNLADDLTNTLKAARSQLIDIEKHLKEPTVLPGP
TGESNILYLENRGNIICFADENVSFHFWLLSVVTALATGNTVISVVSDLFYDQAIAFRDELIATGEDENIFQIARLCHLT
TLLAQPGLSGVVVDSHCDREHYISEKLAERQGAILPVISSKYVDNLMQRLLTEKAVSINTTATGGNTSLMTLDEED

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=479, Percent_Identity=29.2275574112735, Blast_Score=177, Evalue=8e-44,
Organism=Homo sapiens, GI12007648, Length=434, Percent_Identity=28.8018433179723, Blast_Score=171, Evalue=4e-42,
Organism=Homo sapiens, GI25777736, Length=464, Percent_Identity=29.7413793103448, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777734, Length=464, Percent_Identity=29.7413793103448, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI238859541, Length=464, Percent_Identity=29.7413793103448, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI25777730, Length=471, Percent_Identity=29.0870488322718, Blast_Score=167, Evalue=6e-41,
Organism=Homo sapiens, GI21361176, Length=488, Percent_Identity=27.4590163934426, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI25777732, Length=498, Percent_Identity=29.1164658634538, Blast_Score=160, Evalue=9e-39,
Organism=Homo sapiens, GI21614513, Length=420, Percent_Identity=29.7619047619048, Blast_Score=158, Evalue=3e-38,
Organism=Homo sapiens, GI25777724, Length=480, Percent_Identity=28.125, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI238814322, Length=426, Percent_Identity=27.9342723004695, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI115387104, Length=448, Percent_Identity=27.4553571428571, Blast_Score=147, Evalue=6e-35,
Organism=Homo sapiens, GI25777728, Length=436, Percent_Identity=28.6697247706422, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI25952152, Length=432, Percent_Identity=28.4722222222222, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI188035924, Length=451, Percent_Identity=26.6075388026608, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI310128103, Length=451, Percent_Identity=26.6075388026608, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI310128093, Length=452, Percent_Identity=26.5486725663717, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI4507229, Length=420, Percent_Identity=26.1904761904762, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI310128091, Length=390, Percent_Identity=27.6923076923077, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI25777726, Length=480, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI25777721, Length=433, Percent_Identity=25.1732101616628, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI11095441, Length=443, Percent_Identity=25.9593679458239, Blast_Score=115, Evalue=3e-25,
Organism=Homo sapiens, GI4502043, Length=338, Percent_Identity=25.1479289940828, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI238814371, Length=338, Percent_Identity=25.1479289940828, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI310128089, Length=335, Percent_Identity=27.1641791044776, Blast_Score=97, Evalue=9e-20,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=25.1479289940828, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI310128095, Length=313, Percent_Identity=27.7955271565495, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128087, Length=270, Percent_Identity=25.1851851851852, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI206597441, Length=433, Percent_Identity=23.3256351039261, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI206597439, Length=433, Percent_Identity=23.3256351039261, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI22907049, Length=433, Percent_Identity=23.3256351039261, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI73695881, Length=330, Percent_Identity=23.3333333333333, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI73695879, Length=330, Percent_Identity=23.3333333333333, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128097, Length=258, Percent_Identity=28.2945736434109, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI301500698, Length=267, Percent_Identity=24.3445692883895, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI4557303, Length=362, Percent_Identity=22.9281767955801, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI73466520, Length=362, Percent_Identity=22.9281767955801, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI310128099, Length=220, Percent_Identity=24.5454545454545, Blast_Score=73, Evalue=2e-12,
Organism=Homo sapiens, GI310128101, Length=217, Percent_Identity=24.4239631336406, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1787250, Length=1283, Percent_Identity=44.1932969602494, Blast_Score=1006, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=452, Percent_Identity=29.2035398230088, Blast_Score=174, Evalue=3e-44,
Organism=Escherichia coli, GI1787715, Length=414, Percent_Identity=30.4347826086957, Blast_Score=171, Evalue=3e-43,
Organism=Escherichia coli, GI87081896, Length=469, Percent_Identity=29.4243070362473, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI1787558, Length=451, Percent_Identity=30.1552106430155, Blast_Score=166, Evalue=7e-42,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=27.765726681128, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI87082295, Length=426, Percent_Identity=27.2300469483568, Blast_Score=140, Evalue=7e-34,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=27.4553571428571, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786504, Length=449, Percent_Identity=25.1670378619154, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI87081926, Length=405, Percent_Identity=25.679012345679, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17534447, Length=474, Percent_Identity=28.2700421940928, Blast_Score=182, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI133930964, Length=439, Percent_Identity=29.3849658314351, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=401, Percent_Identity=30.4239401496259, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17562198, Length=478, Percent_Identity=28.4518828451883, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25144435, Length=482, Percent_Identity=28.4232365145228, Blast_Score=153, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=461, Percent_Identity=27.114967462039, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32564736, Length=411, Percent_Identity=29.4403892944039, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25143874, Length=438, Percent_Identity=26.9406392694064, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25143876, Length=438, Percent_Identity=26.9406392694064, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=422, Percent_Identity=26.0663507109005, Blast_Score=140, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=425, Percent_Identity=26.5882352941176, Blast_Score=135, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=434, Percent_Identity=25.5760368663594, Blast_Score=126, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=432, Percent_Identity=26.1574074074074, Blast_Score=119, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=385, Percent_Identity=24.9350649350649, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71986308, Length=430, Percent_Identity=26.7441860465116, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=297, Percent_Identity=25.9259259259259, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=432, Percent_Identity=24.0740740740741, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=432, Percent_Identity=24.0740740740741, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=432, Percent_Identity=24.0740740740741, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.7575757575758, Blast_Score=98, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325196, Length=503, Percent_Identity=28.2306163021869, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=476, Percent_Identity=29.6218487394958, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=496, Percent_Identity=30.6451612903226, Blast_Score=161, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=494, Percent_Identity=29.7570850202429, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6320917, Length=455, Percent_Identity=28.1318681318681, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=487, Percent_Identity=28.5420944558522, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=476, Percent_Identity=26.2605042016807, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=451, Percent_Identity=23.059866962306, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323757, Length=337, Percent_Identity=24.9258160237389, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281362580, Length=502, Percent_Identity=27.2908366533865, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472918, Length=502, Percent_Identity=27.2908366533865, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472926, Length=502, Percent_Identity=27.2908366533865, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472936, Length=502, Percent_Identity=27.2908366533865, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356737, Length=502, Percent_Identity=27.2908366533865, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24650465, Length=469, Percent_Identity=28.5714285714286, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585660, Length=461, Percent_Identity=27.5488069414317, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24668425, Length=463, Percent_Identity=27.645788336933, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24668417, Length=463, Percent_Identity=27.645788336933, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24668413, Length=463, Percent_Identity=27.645788336933, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI20129399, Length=474, Percent_Identity=28.2700421940928, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24666674, Length=445, Percent_Identity=27.8651685393258, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571802, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571800, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571798, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571796, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571794, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571806, Length=453, Percent_Identity=23.3995584988962, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24638878, Length=430, Percent_Identity=25.1162790697674, Blast_Score=103, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24638876, Length=430, Percent_Identity=25.1162790697674, Blast_Score=103, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28574525, Length=457, Percent_Identity=21.8818380743982, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281360299, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360297, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360295, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586250, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281360301, Length=425, Percent_Identity=23.2941176470588, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552499, Length=429, Percent_Identity=22.8438228438228, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360303, Length=425, Percent_Identity=23.2941176470588, Blast_Score=80, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140737; Mature: 140737

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFNNSNITASPIRQKIREFYRIDESIAVEHILPLAEVNDNAASRAWEKARKMSMKIRKD
CEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
ESGNGAVDALLAEYTLSSEEGVVLMCLAEALLRVPDKHTQDALISDKISKGQWDSHLGSS
CCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHCCCCC
DSLFVNASSWGLLVTGKMVDYADEREKDSFDLLKKVIGRLGEPVIRKSMNYAMQIMGEQF
CCEEEEECCCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
VMGETIQDATDHAAKKARQGFVYSYDMLGEGARTMSDAEKYFKAYQVAIDAIGAVARASG
HHCCHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KNDPRKVPGISVKLTAIHPRYEFAQKERVMAEVAPKLKALCLQAKSYNIGLTVDAEESER
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
LDISLDVIEAVFSDDELAGWNGFSMALQAYQKRAIFIVDWLRELTIRVDRKMMVRLVKGA
CEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YWDTQIKNSQKGGYQHFPLFTRKASTDVSYIACAKKLLEYRDTIFPQFATHNAYTVATIL
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
ELAGNDKTSFEFQCLYGMGGSLYDQVVTNENVQCRIYAPVGPHEDLLAYLVRRLLENGAN
HHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCC
SSFVNAIIDDSQPIESLLRNPVEKMHSLKDKYNGQIIKPIALYHDQKGVGRDNSKGLDLT
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHEEECCCCCCCCCCCCCCEE
DINTVTPLKTSLDNWLVNNLFSEDDVPEGSIAIRNPAKQSEIIGFQRHHSKDEMLAMVET
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHCCHHHHCCHHHHHHHHHH
AHNAFASWSQTSVSERADLLCRVADVLEHHMDEFIALCIKEAGKTTQDGIDEVKEAVDFC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RYYAQQAIELAEDDRIEARGVVLCISPWNFPLAIFVGQVTAAIATGNTVLAKPAQQTSLI
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
ALRAIELMTSVGLPHGVVQAVIAKGSDVGKVIIPNARIQAVIFTGSIKTATIISQTLADR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHC
GGDQVPFIAETGGQNCMLVDSTALPEQVVDDVISSGFQSAGQRCSALRVLFLQEDIADNV
CCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITMLKGALAELHVGNPEKLSTDVGPVIDQKALDSLNAHSDYMKTHGQLLYQCDISDEITN
HHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEEECCCHHHHH
EIADNEHFFFAPRLYEIENISALKEEVFGPCVHIVRFKGDEIEKVVDDINDTGFGLTMGI
HHCCCCCEEECCCEEEHHHHHHHHHHHHHHHEEHEEECCHHHHHHHHCCCCCCCEEEEHH
HTRIEQRALKLAKLSRAGNVYINRNIIGAIVGVQPFGGRGLSGTGPKAGGPYYLTRLVKE
HHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ITTPAAKKLNLIPQQAEASNSDTDAQAVLFMDKARTAEKIWRLTELNTRISCVSEVLAKI
HCCCHHHHHCCCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHIDIITNLADDLTNTLKAARSQLIDIEKHLKEPTVLPGPTGESNILYLENRGNIICFAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEC
ENVSFHFWLLSVVTALATGNTVISVVSDLFYDQAIAFRDELIATGEDENIFQIARLCHLT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLLAQPGLSGVVVDSHCDREHYISEKLAERQGAILPVISSKYVDNLMQRLLTEKAVSINT
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCEEEE
TATGGNTSLMTLDEED
ECCCCCEEEEEECCCC
>Mature Secondary Structure
MLFNNSNITASPIRQKIREFYRIDESIAVEHILPLAEVNDNAASRAWEKARKMSMKIRKD
CEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECC
ESGNGAVDALLAEYTLSSEEGVVLMCLAEALLRVPDKHTQDALISDKISKGQWDSHLGSS
CCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHCCCCC
DSLFVNASSWGLLVTGKMVDYADEREKDSFDLLKKVIGRLGEPVIRKSMNYAMQIMGEQF
CCEEEEECCCCEEEECCHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
VMGETIQDATDHAAKKARQGFVYSYDMLGEGARTMSDAEKYFKAYQVAIDAIGAVARASG
HHCCHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KNDPRKVPGISVKLTAIHPRYEFAQKERVMAEVAPKLKALCLQAKSYNIGLTVDAEESER
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
LDISLDVIEAVFSDDELAGWNGFSMALQAYQKRAIFIVDWLRELTIRVDRKMMVRLVKGA
CEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YWDTQIKNSQKGGYQHFPLFTRKASTDVSYIACAKKLLEYRDTIFPQFATHNAYTVATIL
CCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHH
ELAGNDKTSFEFQCLYGMGGSLYDQVVTNENVQCRIYAPVGPHEDLLAYLVRRLLENGAN
HHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCC
SSFVNAIIDDSQPIESLLRNPVEKMHSLKDKYNGQIIKPIALYHDQKGVGRDNSKGLDLT
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHEEECCCCCCCCCCCCCCEE
DINTVTPLKTSLDNWLVNNLFSEDDVPEGSIAIRNPAKQSEIIGFQRHHSKDEMLAMVET
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHCCHHHHCCHHHHHHHHHH
AHNAFASWSQTSVSERADLLCRVADVLEHHMDEFIALCIKEAGKTTQDGIDEVKEAVDFC
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RYYAQQAIELAEDDRIEARGVVLCISPWNFPLAIFVGQVTAAIATGNTVLAKPAQQTSLI
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
ALRAIELMTSVGLPHGVVQAVIAKGSDVGKVIIPNARIQAVIFTGSIKTATIISQTLADR
HHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHC
GGDQVPFIAETGGQNCMLVDSTALPEQVVDDVISSGFQSAGQRCSALRVLFLQEDIADNV
CCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITMLKGALAELHVGNPEKLSTDVGPVIDQKALDSLNAHSDYMKTHGQLLYQCDISDEITN
HHHHHHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEEECCCHHHHH
EIADNEHFFFAPRLYEIENISALKEEVFGPCVHIVRFKGDEIEKVVDDINDTGFGLTMGI
HHCCCCCEEECCCEEEHHHHHHHHHHHHHHHEEHEEECCHHHHHHHHCCCCCCCEEEEHH
HTRIEQRALKLAKLSRAGNVYINRNIIGAIVGVQPFGGRGLSGTGPKAGGPYYLTRLVKE
HHHHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ITTPAAKKLNLIPQQAEASNSDTDAQAVLFMDKARTAEKIWRLTELNTRISCVSEVLAKI
HCCCHHHHHCCCCCHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHIDIITNLADDLTNTLKAARSQLIDIEKHLKEPTVLPGPTGESNILYLENRGNIICFAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEEEC
ENVSFHFWLLSVVTALATGNTVISVVSDLFYDQAIAFRDELIATGEDENIFQIARLCHLT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLLAQPGLSGVVVDSHCDREHYISEKLAERQGAILPVISSKYVDNLMQRLLTEKAVSINT
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCEEEE
TATGGNTSLMTLDEED
ECCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]